House holiday rentals in Los Santos

Find and book unique houses on Airbnb

Top-rated house rentals in Los Santos

Guests agree: These houses are highly rated for location, cleanliness and more.

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Superhost

The house exterior features a warm peach-colored facade with a large white-framed window. Tropical palm trees and vibrant flowering shrubs border the front, providing a refreshing touch to the entrance.

Home in Chitré

NinaHouse, casa amplia y fresca en Chitré.

Casa solo para ti, ahora con tanque de agua!hasta 7 p, amplia y en una de las mejores zonas de Chitré, tranquila y familiar, acceso a la piscina del area social, parques y canchas, cerca de todo: supermercados, casino, bus; ven a Chitre y disfrutar de comidas típicas, artesanía; planifica tus paseos y visita las mejores playas: Pedasi, Venao, Isla Iguana, podrás trabajar desde NinaHouse contando con un rápido internet. Ahora contamos con aire acondicionado en la sala para tu confort.

ValueFamilyBathroom

4.82 out of 5 average rating, 84 reviews

Superhost

A single-story house with a red-tiled roof and beige exterior is featured. Two white columns support a covered entrance, and a small plant is positioned near the front door. The driveway is made of concrete, leading up to a well-maintained yard with green grass.

Home in Monagrillo

Nuestro Lugar Feliz

Relájate con toda la familia en este tranquilo lugar para quedarse. Es una residencia unifamiliar, en la recámara principal mantenemos una cama Queen (1.50 m x 1.90 m) en la segunda habitación mantenemos 2 camas Twin (90 m x 1.90 m). En la residencia mantenemos disponibilidad para 4 personas cómodamente, sin embargo mantenemos un sillón cama y una cama tipo Pee disponible para 2 personas adicionales. Consulta el pequeño costo adicional por las personas adicionales.

LocationValueSleep quality

4.83 out of 5 average rating, 54 reviews

Guest favourite

A single-story house is nestled beneath a large tree, featuring a tiled roof and a covered parking area. Surrounding greenery includes bushes and ornamental plants, enhancing the natural setting. The house is positioned to provide a sense of privacy and tranquility.

Home in Chitré

Country House Like in the City / La Casita

Casa fresca, con árboles, naturaleza y portales p/ descansar, cámaras de seguridad afuera Ubicación céntrica, cerca de malls, restaurantes, buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Contamos con un pozo de agua y sistema de purificación de agua por ósmosis inversa: agua segura, potable y purificada!

FamilyValueWi-Fi

4.87 out of 5 average rating, 70 reviews

Guest favourite

Home in Chitré

Casa Blu Central Chitre| Sleeps 6| Private Parking

Stay in a newly renovated private home in the center of Chitré with free gated parking, a large backyard, fast Wi-Fi, and space for the whole family. Walk to restaurants, supermarkets and the cathedral while enjoying the comfort of an entire home to yourselves. It combines comfort, spaciousness, and natural light in every corner — perfect for families or groups of friends looking for a place that feels just like home.

FamilyLocationDecor

5.0 out of 5 average rating, 11 reviews

Home in Chitre

Chitré Oasis: Modern Home with Private Pool & BBQ

Welcome to your private oasis in Chitré 🌴 Soak up the Azuero sun in our stunning pool 🏊‍♂️ and unwind on the covered terrace with a BBQ area 🍖, perfect for grilling and outdoor dining. The house is strategically located in a very safe residential area, just minutes away from Mall Paseo Central, Riba Smith supermarket, and the vibrant downtown Chitré 🛍️. Featuring modern spaces and full A/C.

ValueFamilyCleanliness

4.72 out of 5 average rating, 43 reviews

Guest favourite

Home in Chitré

Residencia Alsol | Chitré Centro

Casa espaciosa y equipada en zona céntrica de Chitré. 3 recámaras con A/C, 2.5 baños, Cocina completa, Wifi rápido, Balcones y parking techado. Ideal para familias, grupos o viajes de trabajo. Spacious house, Fully equipped home in central Chitré. 3 A/C bedrooms, 2.5 baths, full kitchen, Fast wifi, Balconies and covered parking. Perfect for families, groups or business trips.

LocationGetting aroundComfort

5.0 out of 5 average rating, 6 reviews

The exterior of the house is showcased with a modern design, featuring a white facade and large windows. A covered terrace is visible, providing a shaded area, while a well-kept lawn surrounds the property. A parking space accommodates multiple vehicles.

Home in Chitré

Minimalist House In Chitre

THIS STYLISH PLACE TO STAY IS PERFECT. CENTRAL CHITRE: THE HOUSE IS IN A DEAD END, SUPER SAFE AND QUIET NEIGHBORHOOD ONLY 2 BLOCKS FROM MARKET SUPER CARNES FEATURES: 2 BEDROOMS WITH A/C ONE BATHROOM: KITCHEN, LIVING ROOM, TERRACE, PARKING FOR 4 CARS. WASHING MACHINE AND DRYER MACHINE, HOT WATER, WATER RESERVE TANK 2600 LITER, CENTRAL ALARM SYSTEM ENTIRE HOUSE

LocationFamilyAir conditioning

4.92 out of 5 average rating, 12 reviews

Home in La Villa de Los Santos

Casa para grupos/Perfecta para Fiestas Locales

Looking for comfort, privacy, and great value? ✨🏠 Enjoy a home designed for relaxing after a day of work, sightseeing, or exploring Azuero’s events. It features air-conditioned bedrooms, Wi-Fi, a fully equipped kitchen, washer and dryer. Perfect for Carnival, Azuero Fair, Holy Week, Corpus Christi, Campesino Week, and more.

LocationValueBathroom

4.68 out of 5 average rating, 19 reviews

Guest favourite

Home in La Villa de Los Santos

Casa familiar para 8 | 3 habitaciones con a/c

Casa completa para hasta 8 huéspedes en Los Santos. A solo minutos de la Feria de Azuero. Disfruta de 3 habitaciones con aire acondicionado , baños, WiFi de alta velocidad, cocina equipada y estacionamiento privado. Ideal para familias, grupos y viajeros que buscan comodidad y excelente ubicación.

ValueLocationAccuracy

4.88 out of 5 average rating, 8 reviews

Guest favourite

Home in La Villa de Los Santos

Amplia casa Villa de los Santos

Cómodo alojamiento familiar en La Villa de Los Santos, con Wi-Fi, A/C, cocina equipada, patio y estacionamiento. Ubicado cerca de supermercados y plazas. A solo 15 min de El Rompió y Monagre, 45 min de Isla Iguana y 1h 30 min de Playa Venao.

ValueFamilyGetting around

4.93 out of 5 average rating, 118 reviews

Superhost

A modern living space features a plush gray sofa paired with a rustic wooden coffee table, accented by a decorative elephant. The open kitchen showcases dark cabinetry, stainless steel appliances, and stylish pendant lighting, while an elegant mirror reflects the inviting atmosphere.

Home in Los Olivos

Luxury Villa

Villa amoblada de lujo, con piscina al salir de la puerta. Lugar mágico para pasar en familia, pareja o amigos. 2 recamaras, 1 Baño, amoblada, parking comun. Es el lugar ideal para descanso, sin duda la mejor villa del condominio .

Top Guest favourite

Home in Chitré

Santa Clara Chitré

Espacio acogedor, perfecto para compartir en familia, excelente ubicación. Cerca de supermercado, área bancaria, universidad, terminal de transporte, estación de gasolina.

FamilyLocationComfort

4.87 out of 5 average rating, 85 reviews