
Boutique hotel holiday rentals in Iowa
Find and book unique boutique hotel rentals on Airbnb
Top-Rated Boutique Hotels in Iowa
Guests agree: These boutique hotel rentals are highly rated for location, cleanliness and more.

Stylish Modern Room for an Ideal Stay! Free Coffee
Our property is conveniently situated in the Downtown Des Moines part of Des Moines. This establishment boasts an amazing location, connected to the Des Moines Skywalk system and just steps from popular destinations, including the Wells Fargo Arena, the Iowa Events Center, the Des Moines Performing Arts Center, the Court Avenue Entertainment District, and many businesses, as well as the East Village. We provide a complimentary airport transfer for your convenience. It is a pleasure to serve you!

Inn of the Six-Toed Cat -- Rosalie Room
Inn of the Six-Toed Cat, where you can take life a little slower at an authentic turn of the century Inn. We have common rooms for guests to relax, read, play games or watch TV/movie. We provide a wonderful breakfast with warm hospitality. Near by is the highly acclaimed Prairie Trails Museum (in Corydon), Bob White park, Round Barn, Amish country, golfing and lost of little antique stores in the neighboring towns. Come enjoy the front porch lifestyle, and let us be your home away from home.

American House 1854- Stagecoach Stop Suite
Take in the beauty of the Mississippi River at this unique and tranquil getaway. The American House Inn is the oldest standing building in McGregor, IA. Built in 1854, this building is on the National Registry of Historic Places and takes you back to the late 1800s but with modern amenities. Located just across the street from Big Bouys Marina, Kwik Star and a block from the Sadie’s Sweet Ice Cream shop! You don’t want to miss enjoying all of the history and the beauty of this vintage gem!

The Mainline Depot Pedersen Suite for 2
You will feel right at home in this charming luxury studio apartment suite located in an old 1900's Farmer's State Bank. This unique suite has a queen sized bed with a stunning antique chandelier. There is a full sized kitchen with quartz counters that has everything you need and an inviting dining room to eat your meals. Snuggle up on the stylish sofa and enjoy the a cozy electric fireplace and cable TV. (See separate listing to include the bunk room that sleeps an additional 6 guests!

Private Townhome Apartment in Historic Hotel
Offering elegance, history, and genuine hospitality, The Continental Hotel is southern Iowa’s premier boutique hotel. A hidden gem on the historic Centerville Square, our 28-room hotel dates to 1866. We have hosted a number of famous historical figures including Booker T. Washington and Carrie Nation. The Continental has a restaurant, Lucile's, on the main level that serves lunch and dinner. Free continental breakfast is available here and is included with your stay.

River View Lodge - King Suite 202
Welcome to our luxurious King Suite! This elegant suite features a king-size bed, perfect for a restful night's sleep, and a sofa bed for extra guests. The highlight of the suite is the indulgent jetted tub, where you can unwind and relax after a long day. The large walk-in shower offers a refreshing and invigorating experience. Enjoy entertainment on the flat screen TV and stay connected with free WiFi!

Charming Boutique Country Estate with a pool
No detail is overlooked at this charming and upscale country estate to stay. We have an indoor pool, outdoor basketball courts and pickleball courts, Trager grills available for guests use, outdoor dining area. Plenty of space for your furry friends, we're pet friendly and sit on 10 acres right on the edge of Waverly. Outdoor dog park, book your stay today.

King Suite - Dodici Night Suites
Above the famous Dodici Cafe Restaurant in beautiful downtown Washington, This suite is newly built in 2016. King size bed with sitting area and bath Extra bedroom with queen size bed Other Amenities: Private Bath with Hair Dryer and Bath Products, Air-conditioning, Refrigerator, Microwave, Coffee Maker, Dining Table, TV, Free Wi-Fi

The Monticello Motel
A boutique 1950’s roadside motel offering upscale amenities like premium snack trays. Including common areas that are ready to unwind in with your friends and family. Rent the entire property for your next small gathering or girls trip. This hip spot offers more than just distinctive decor. It’s unlike any motel you’ve never stayed at before!

Lakeside Inn - Clear Lake - Standard King
Charming king room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. Offering an array of rooms, some with patios, we are here to make your stay an experience to remember.

Lakeside Inn Clear Lake, IA Queen Obstructed View
Pleasant double queen room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. This room does have an obstructed view of the lake from the room.

Welcoming Suite Near Coca-Cola Museum – 7 Min Walk
Located off Highway 6, explore downtown Iowa and Atlantic Coca-Cola Museum. Perfect for business travelers near Iowa Western Community College. You’ll also find yourself close to Walmart, restaurants, and gas stations.
Popular amenities for Iowa Boutique Hotels
Family-Friendly Boutique Hotels

4 Inviting Rooms Near Lake Anita State Park

Easy Highway 6 Access from 2 Suites w/ Breakfast

Unique Stays by the Missouri River, Wild West XP

Expanded King Bunk Bed Suite, Stoney Creek

Family-Friendly Sioux City Stay, 2 Pools | 3 Units

Comfortable Room w/ BBQ Grill Near Hwy 6 - Parking

Expanded King Bunk Bed, Stoney Creek | 2 Units

Expanded King w/ Whirlpool Cottage | 2 Units
Other boutique hotel holiday rentals

Theme Suite w/ Whirlpool & Fireplace, Stoney Creek

Deluxe 2 Double, Parking, Stoney Creek Johnston

Unwind in Style: Pool, Gym & Free Hot Breakfast

Expanded King Bunk Suite, Stoney Creek, Bunk Bed

Serene Stay: Fitness, Fun, & Free Hot Breakfast

Spacious Rooms: Near Wells Fargo & Art Center

Relaxing Stay! Pool, Free Parking, Pets Allowed!

Cosy Gateway w/ Heated Pool & Fireplace | 2 Units
Destinations to explore
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- Boutique hotel rentals United States