House holiday rentals in Durham County

A modern duplex with a welcoming front porch is showcased. The porch features wooden railings and potted plants on either side. A clear pathway leads to the entrance. The structure is set against a backdrop of trees and an expansive yard.

4.94 out of 5 average rating, 156 reviews

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

The exterior of the bungalow is presented, showcasing a well-maintained side with fresh white siding and a new roof. A welcoming red front door is highlighted, flanked by small shrubs and decorative landscaping. Tall trees are visible in the background, adding natural greenery.

4.96 out of 5 average rating, 180 reviews

Mirabelle- 3bd Downtown/Duke/RTP/No Cleaning Fees

Step into the comfort of this stylish, newly renovated 3- bedroom, 1- bath bungalow! CENTRALLY LOCATED & NEAR ALL MAJOR HIGHWAYS, Mirabelle is just minutes from downtown Durham, Duke University & RTP. No matter what brings you to Durham, Mirabelle has the perfect location & convenient amenities you’re looking for! * 5 min from downtown Durham * 10 min from Duke University & Duke Hospital * 10 min from RTP * 15 min from RDU airport * 10 min from Durham bulls and DPAC * 15 min from UNC hospital

4.96 out of 5 average rating, 179 reviews

Luxury Modern Suite W/ Private Deck

Welcome to our Private Luxury Master Suite! Enjoy a hotel-like experience with a spacious luxury bath featuring double sinks and a rain shower and a beautiful private deck with a peaceful view. We also include a coffee bar, work area, Wi-Fi, and TV. Conveniently located from RDU Airport and Downtown Durham, with a variety of restaurants and coffee shops nearby. Experience the perfect blend of comfort, luxury, and convenience in this upgraded suite! Parking is available and limited to 1.

A spacious living area is highlighted by a vibrant orange couch adorned with decorative pillows. Large windows fill the space with natural light, complemented by green plants that bring a touch of nature indoors. The open layout leads to a modern kitchen in the background.

4.98 out of 5 average rating, 274 reviews

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

A screened porch is illuminated by soft string lights, casting a warm glow against the exterior of the house. The porch features wooden furniture, and a well-maintained lawn is visible in the foreground. A tall tree provides shade beside the porch.

4.98 out of 5 average rating, 129 reviews

Near Duke, Southpoint, UNC

Discover the perfect retreat in South Durham, NC! Our tranquil Airbnb offers an idyllic escape with a prime central location that guarantees a memorable stay. Start your morning on the inviting screen porch, where you can relish a cup of coffee and take in the view of the flower garden before headed out to enjoy some of the Triangle's finest attractions. Convenience is at your fingertips, as our Airbnb is just minutes away from RTP, RDU airport, Downtown Durham, DUKE, UNC, and the DPAC.

Superhost

The kitchen area features white cabinetry and a wooden countertop. A modern fridge is positioned next to the entrance door, leading to a cozy living area with a brown sofa and a bright red chair. A colorful wall art piece adds a touch of decoration.

4.9 out of 5 average rating, 232 reviews

Clean Quiet Medical&Work Stay, Fenced Yard, Pets

Welcome to a spotlessly clean, quiet, and comfortable home in downtown Durham, thoughtfully set up for medical stays, longer work visits, and guests traveling with pets. Many guests choose this home while visiting Duke University Hospital, the VA Hospital, or Duke University, and appreciate having a calm place that feels easy to live in during what can be stressful or busy times. This is not a party house —it’s a peaceful, practical space designed to help you rest, reset, and settle in.

4.93 out of 5 average rating, 128 reviews

Home in Chapel Hill

Chapel Hill/Durham retreat: Hot-tub, Massage chair

Enjoy the spa-like amenities of this tastefully remodeled private home nestled amongst the trees. Close to Chapel Hill and Durham. Enjoy the hot tub, spa robes, massage chair, 120' projector TV (Netflix included,) remote-controlled gas fireplace. 800 thread count sheets and comfortable beds ensure a good nights sleep. Caribou coffee pods and grounds get your day started. Close to Chapel Hill and Durham. Pets stay free and enjoy a fenced yard. Just please dont let them on the furniture

The exterior entrance features a vibrant coral door set against a light grey shiplap facade. Above the door, a decorative archway frames the house number. Two wall sconces flank the door, providing illumination, while the door is surrounded by well-maintained vegetation.

4.98 out of 5 average rating, 139 reviews

Warm and Welcoming 3-Bedroom Cottage

Welcome to Carolina Cottage, nestled in one of Durham's premier post WWII neighborhoods, and extensively renovated by Designer + Builder Alicia Hylton-Daniel. Your experience will be enhanced by the thoughtfully curated spaces for relaxing, renewing and re-connecting. The home is spacious, with common areas to be shared, inside and out, as well as quiet spaces to read, nap, scroll and stream. You'll enjoy a full chef's kitchen and dining room, along with a sunny porch and shaded patio.

A cozy living area is highlighted by an inviting red sofa and a flat-screen TV mounted on the wall. Natural light filters in through a nearby window, while a kitchenette with a microwave and mini-fridge is positioned on a shelving unit. Exposed wooden beams add character to the high ceiling.

4.92 out of 5 average rating, 123 reviews

Guest Suite: Artist studio turned into loft.

A guest suite that's a former artist studio with 10-15 foot high windows and 20 foot high ceiling, converted into one bedroom loft with private entrance, bath, living area, and kitchenette. The space is attached to the rest of my house, but you'll have a private entrance, your own bathroom, living area and kitchenette and two seat dining table. You will not have access to a full kitchen. The open-concept design and high balcony ledge are unsuitable for children under the age of 10.

The exterior of a renovated single-story home is presented, featuring a neutral color palette and a well-maintained yard. A front porch with black railings is visible, alongside inviting landscaping. A gravel driveway leads to the entrance, surrounded by trees providing a natural backdrop.

4.92 out of 5 average rating, 130 reviews

Newly Renovated 3 BR home in convenient location!

Newly renovated space to relax and explore the best of Durham. Sleeps 6 with plenty of space to spread out. Well located - only 10 minutes to Duke, Duke Hospital, downtown and Ninth/Broad Street areas. Enjoy use of the fully stocked kitchen, comfortable living area, dining space and spacious back deck and screened in porch. Grill out and enjoy the back yard. Great for families and groups of friends or business travelers. Several restaurants close by and easy access to highways.

4.95 out of 5 average rating, 304 reviews

Perfectly Appointed @ Duke-Blue Devil Living!

Experience Duke at its best from our centrally located duplex between East & West Campus. With the campus bus stop right outside, easily explore Duke, Durham's museums, and local restaurants. Enjoy the perfect blend of comfort and style, featuring Little Waves coffee, a retro bathroom with eco-friendly products, and hotel-quality bedrooms. Duke Hospital is just minutes away, making our home ideal for your stay. Live like a Blue Devil at the heart of Duke and Durham. Book now.

The modern kitchen features an expansive island with a white countertop and light wood cabinetry. Pendant lights hang above, while stainless steel appliances, including a double oven, are integrated into dark cabinetry. A living area is visible in the background, illuminated by natural light.