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Guesthouse holiday rentals in Doña Ana County

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Doña Ana County

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
Guesthouse in Las Cruces

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

LocationFamilySolo travel

4.96 out of 5 average rating, 269 reviews
Top Guest favourite
The kitchen features white cabinetry with glass-fronted doors, a granite countertop, and stainless steel appliances. A decorative rug lies on the floor, while plants and artwork add touches of color. Ample natural light illuminates the space, creating a welcoming atmosphere for meal preparation.
Guesthouse in Mesilla

Relax in the ❤️ of Old Mesilla. Close to plaza.

Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

ValueFamilyOutdoor spaces

4.96 out of 5 average rating, 112 reviews
Guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guesthouse in Las Cruces

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

ValueFamilyHeating

4.94 out of 5 average rating, 181 reviews
Top Guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guesthouse in Las Cruces

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

FamilyValueCondition

4.98 out of 5 average rating, 254 reviews
Top Guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

ValueFamilyBarbecue

5.0 out of 5 average rating, 297 reviews
Top Guest favourite
The exterior of a historic adobe building is captured during twilight, highlighting the unique architectural features. A welcoming glow emanates from a window, revealing the vibrant colors of the paintings nearby. The surrounding courtyard includes a mix of textures and shaping, emphasizing the enchanting atmosphere.
Guesthouse in Hatch

Casita at Old Mission near Hatch NM

Have you stayed overnight in a Church before? This is your opportunity. Your lodging in the Casita is attached to the now deconsecrated St Francis de Sales Church, surrounded by a large Spanish courtyard, garden, and a private patio and parking area. Experience the adobe spaces as built in 1860. The church compound is walled and gated. We are located 1 1/2 miles southeast of Hatch in a colonia called Rodey. Look for the bell tower from Hwy 185 and begin your experience here.

FamilyLocationAccess

4.96 out of 5 average rating, 166 reviews
Top Guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

ValueLocationLayout

4.97 out of 5 average rating, 414 reviews
Top Guest favourite
A tranquil sleeping area features a spacious bed adorned with decorative pillows and a handwoven wall hanging above. Soft lighting from an ornate chandelier complements the adobe walls, while a rustic table and chairs anchor the inviting space.
Guesthouse in Las Cruces

Clara's Nest - The Gem of Hacienda de las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

FamilyLocationLayout

4.97 out of 5 average rating, 372 reviews
Top Guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces

Cozy Casita w/private patio near Old Mesilla

This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

FamilyValueNearby

4.96 out of 5 average rating, 398 reviews
Top Guest favourite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Mesilla

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

FamilyValueParking

4.99 out of 5 average rating, 224 reviews
Top Guest favourite
The exterior of the casita is presented, featuring a covered porch supported by wooden beams. A light-colored door and two large windows are visible, reflecting soft sunlight. Decorative plants in pots are positioned nearby, enhancing the natural desert aesthetic.
Guesthouse in Las Cruces

Casa Majik

A two bedroom casita with a kitchen. We have a full bath with tub and shower. Very quiet upscale neighborhood with all custom homes on 1 acre lots. Winding streets perfect for walking or biking. Less than 50 feet from the door of Casa Majik is a trail leading to "A" Mountain. Parking is for a maximum of two cars on the property. Restaurants and Memorial Hospital are 2 miles away.

LocationFamilyBiking

4.88 out of 5 average rating, 192 reviews
Top Guest favourite
Guesthouse in Las Cruces

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

LocationValueAccess

4.94 out of 5 average rating, 249 reviews

Popular amenities for Doña Ana County guesthouses

Family-Friendly guesthouses

Guesthouses with a patio

Top Guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guesthouse in Central El Paso

Private studio w/ scenic view near downtown

ValueLocationParking

4.93 out of 5 average rating, 240 reviews
Top Guest favourite
An outdoor patio is presented with a hot tub, a grill, and seating arrangements. The area is enclosed by walls, featuring vibrant green accents. A colorful sunset sky adds warmth to the scene, enhancing the relaxing atmosphere of the private courtyard.
Guesthouse in Mesilla

Casita de Colibrí | Hot Tub • Walk to Old Mesilla

LocationViewWalkability

4.99 out of 5 average rating, 283 reviews
Top Guest favourite
A cozy living area is presented with a modern grey sofa, adorned with patterned cushions. A wooden coffee table sits centrally, with a decorative star piece on top. Natural light filters through large windows, revealing a private outdoor space. A pet dog is visible on the floor.
Guesthouse in Central El Paso

Stylish Casita in the Heart of El Paso

FamilyValueCheck-in

4.98 out of 5 average rating, 257 reviews
Guest favourite
A modern living area is featured, showcasing a navy blue sofa and a light-colored armchair. A round coffee table rests on a textured rug. A small desk with a chair can be seen, alongside a large window framed by light curtains, allowing natural light to enter.
Guesthouse in Central El Paso

Modern Studio in Nice Location

LocationFamilyCleanliness

4.97 out of 5 average rating, 264 reviews
Top Guest favourite
A functional kitchen area is equipped with modern appliances and granite countertops. A dining table with four chairs sits against a teal wall, while a cozy seating area features a dark couch adorned with decorative pillows. Natural light enters through partially opened blinds.
Guesthouse in Central El Paso

Cozy Guesthouse - Central EPTX

ValueLocationCheck-in

4.94 out of 5 average rating, 253 reviews
Top Guest favourite
A cozy bedroom features a queen-size bed decorated with floral bedding. Soft light enters through two sets of wooden shutters. A small bedside lamp and a dresser provide functional elements. A circular rug adds warmth to the polished floor.
Guesthouse in Central El Paso

Cozy one bedroom modern mountain view suite!

ValueFamilyAccess

4.94 out of 5 average rating, 140 reviews
Top Guest favourite
The spacious living room features a comfortable gray sofa, a round coffee table, and a television on a white media console. Light wood flooring complements the soft yellow walls. A ceiling fan contributes to the airy ambiance, while a doorway leads to a well-equipped kitchen.
Guesthouse in Central El Paso

Private Guesthouse | Fort Bliss • Shopping • Patio

FamilyLocationOutdoor spaces

4.88 out of 5 average rating, 98 reviews
Guest favourite
A dining area is highlighted by a round wooden table seated by four chairs. The wall features a soothing green panel, and natural light streams in through a window. A pendant lamp hangs overhead, providing a warm, inviting glow to the space.
Guesthouse in Mesilla Park

Dream House - Seen On Visit Las Cruces YouTube

FamilyLocationIndoor spaces

4.91 out of 5 average rating, 92 reviews

Guest house rentals with a washing machine and dryer