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Guesthouse holiday rentals in Doña Ana County

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Doña Ana County

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
A modern studio layout is displayed, featuring a spacious bed with neutral bedding accented by red pillows. A sleek kitchen area with dark wood cabinets, stainless steel appliances, and a small dining area are visible, along with a comfortable seated area in the background.
Guesthouse in El Paso
4.98 out of 5 average rating, 153 reviews

The Burning Tree Studio

This unique West El Paso studio has a modern & minimalist style featuring refrigerated air, travertine floors, granite countertops with modern dark wood kitchen cabinets and a small dining/work area. Features a queen size bed, a sofa bed that sleeps 1, an individual sleeper module for 1, and plenty of closet space. The large bath has travertine floors and walls and a rain shower with thick glass sliding barn doors, and a stackable washer dryer for your convenience. 60" smart TV with internet.

Top Guest favourite
The kitchen features white cabinetry with glass-fronted doors, a granite countertop, and stainless steel appliances. A decorative rug lies on the floor, while plants and artwork add touches of color. Ample natural light illuminates the space, creating a welcoming atmosphere for meal preparation.
Guesthouse in Las Cruces
4.95 out of 5 average rating, 110 reviews

Relax in the ❤️ of Old Mesilla. Close to plaza.

Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Top Guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 222 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Top Guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 292 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top Guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top Guest favourite
A tranquil sleeping area features a spacious bed adorned with decorative pillows and a handwoven wall hanging above. Soft lighting from an ornate chandelier complements the adobe walls, while a rustic table and chairs anchor the inviting space.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 362 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guesthouse in Las Cruces
4.97 out of 5 average rating, 380 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top Guest favourite
A charming path leads to the entrance of the guest house, framed by blooming flowers and greenery. Decorative plants line the walkway, while a rustic wooden chair sits invitingly on the porch. The structure features adobe-style architecture under a clear blue sky.
Guesthouse in Las Cruces
4.93 out of 5 average rating, 131 reviews

1 bed cute casita near NMSU, pet friendly

Amazing details throughout this small but mighty space. You have all you need for a quick trip or a longer stay. 1 bedroom with a queen, full-sized kitchen, living room, and dining space as well as a fully fenced, pet-friendly yard. Be immersed in local culture with Talavera tile and Saltillo floors as well as vigas and rough-hewn ceilings and accent walls. The guest house is close to the main house but completely separate and private. Off-street, private parking.

Top Guest favourite
A private hot tub is positioned under a wooden pergola with string lights, creating a serene outdoor space. The area features a fire pit nearby, with a scenic view of mountains and city lights visible in the background, illuminated at dusk.
Guesthouse in El Paso
4.92 out of 5 average rating, 227 reviews

Private studio w/ scenic view near downtown

Relax in this cozy studio apartment attached to a beautiful home with access to hot tub and abundant scenic views. Nestled in the Franklin mountains, you can enjoy hiking trails and the famous Scenic Drive. A 2-minute drive to downtown you will find authentic cuisine and nightlife. Close to UTEP, hospitals and international bridge, this property is located in the heart of the city. Free parking, Wi-Fi, and coffee bar with many selections!

Top Guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 255 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top Guest favourite
The historic Old Spanish Mission building is illuminated against a twilight sky, showcasing its unique architectural features. The white stucco exterior is complemented by natural landscaping and a gravel driveway, inviting guests to explore the surrounding area.
Guesthouse in Hatch
4.95 out of 5 average rating, 113 reviews

Historic Mission - Priest's Quarters-1BR, 1Bath

Located near Hatch, New Mexico...the Chile Capital of the World...is an Old Spanish Mission built in 1860. St Francis de Sales stopped being an active church in 1963, but still retains its special flavor unique to southwest New Mexico. Come stay in the Colorado Room located within the Rectory (priest's quarters) on the property. Everyone enjoys a one-of-kind experience here. You will, too.

Top Guest favourite
A warm sleeping area features a queen bed with a neutral quilt and accent pillows. Two bedside lamps illuminate the space with soft light. The ceiling showcases rustic wooden beams, while a framed artwork hangs above the bed, complemented by a textured area rug beneath.
Guesthouse in Las Cruces
4.95 out of 5 average rating, 210 reviews

Rustic Downtown Hideaway

This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Popular amenities for Doña Ana County guesthouses