
Apartment holiday rentals in Clayton
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Clayton
Guests agree: These apartments are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Clayton apartment rentals
Weekly apartment rentals

Apartment in University City
We had a great stay. The house was very clean and the bed really confortable. Landon and Yi were very friendly.

Eskimo Inn Studio Apartment
I’ve stayed here before, would stay again. It’s a great location for me to visit family and the spaces have everything I need. Thanks again!

Oversized 1 Bd 1 Bath Long Stays Lafayette Square
The place was great! Clean and neat. Much bigger than it looks in the pics. Would definitely book again!!

Relax into Contemporary Loft-Style Living on Antique Row
Impeccably clean loft-style space in a cute and walkable neighborhood. Hosts were VERY quick and helpful to respond when one issue (not their fault) came up. Would stay here again!

Cozy Duplex I Centrally Located
We had such an enjoyable stay! The location was great and the home was beautiful and cozy. We felt right at home. The only issue we had were the upstairs neighbors early in the morning but that was no fault of this host. We look forward to visiting again!!

Upscale Ole School 3b/1b WashU, Forest Park, Loop
Great location for a walk to our Concert at Delmar Hall. We had a blast and loved the place. Shower is an eagle claw tub and difficult to use is my only heads up, otherwise, it was Great!!!

Lovely Lafayette Square 1-BR Apt with Garden
As someone who used to live in St. Louis this is perfect location wise! Really enjoyed my stay here and would highly suggest staying here. The hosts are very nice. Quick access to coffee, bars, world class food etc. HIGHLY RECOMMEND staying at Kathryn’s !

1 BR Loft Near Central West End, Walk to BJC
Greg was awesome and responsive with his instructions to get in. Even though his instructions were clear on how to get in, I got lost and confused and he was immediately messaging me how to get in. AWESOME AND COOL PLACE
Private apartment rentals

Large, Woodsy, Warm and Inviting | Cozy 2BR Apt
Great place. Great location. Our hosts were very responsive. I would definitely stay here again.

Welcome to your ideal stay!
It's a wonderful place that I lived almost four months in here. It's clean and calm and with all sufficient appliances and supplies to support a convenient life. The owner is very kind and helpful as well.

*SAFE Soulard 1bd1bth APT / 5 mins frm Dwntwn STL*
Logan’s place was a gem in Soulard! It was easy to find, very clean and close to a lot of local spots. I would stay here again in the future.

Gorgeous Flat by TG Park: Favorite in Shaw!
We had an excellent week-long stay in this well furnished apartment situated in a beautiful neighborhood. It was super clean, has modern appliances and a well-functioning (and quiet!) AC system. But I especially liked all the little things that make a huge difference: extra towels, plenty of hangers in the large closet, lots of drawer space in the bedroom, nightstands on both sides of the bed with lamps and USB outlets, a great hairdryer with separate controls for heat and fan, a sunny laundry room with laundry supplies, a bottle of wine…I could go on and on. I will definitely book this place again.

Spacious Modern Style 1BR furnished+ Balcony
Awesome! Everything as described. That’s why I’m still here.

Modern Apartment near The Hill; Bright,Quiet,Cozy!
I stayed here as an extended stay of around 2.5 months and I would easily recommend this airbnb to anyone: Peggy went above and beyond to not only make it feel like home, but also made sure that there were no everyday needs to worry about. Extremely responsive and proactive with communication. The place was clean, cozy, with great wifi, and with laundry/cleaning supplies/cooking basics included as if it were my own home. The kitchen is a little dated, but never stopped me from doing what I needed. The location is gorgeous and near parks (and a 10 min drive for the hospital, where I worked) and I never had any issues with parking. Very safe as well! The place itself is cute and cozy and the temperature control works very well. Plenty of storage space as well. Honestly I could say many good things as they come to me, but in the end I just truly recommend this place!

Charming Apartment in Historical Small Town by STL
Enjoyed my stay. It's on a quiet street and within walking distance to many good restaurants. The hosts answered questions quickly. Worth staying.

Spacious Home Away from Home
This was exactly what my daughter was looking for! Perfect say for her 19th birthday. She loves old buildings downtown and this was perfect! Such a perfect location too!
Apartment rentals with a hot tub

“Saint Louis Luxe 1BR Retreat”
it was a great place to stay i enjoy myself. we didn't get a change use the hot tub but the pool made up for that because it felt like an hot due to it being heated but very good place to stay 👌

Pleasure Suite
This place was great for our visit to WashU. It was spacious, trendy, comfortable and clean. The building had a lot of cool spaces and amenities that we didn't get a chance to take advantage of but I would encourage others to save some time to utilize. It is an extremely walkabout area, right next to the park and a quick drive for us to WashU. Urus was accommodating to our early arrival which is always appreciated.

Cozy 2 Bedroom King bedroom, queen bed, sofa beds
I was in town visiting family and the location was convenient for my family. There were several restaurants within walking distances and a grocery store and drugstore store right around the corner.

Near City Garden Garage Parking
Looks even better than the pictures. TheSTAY is very responsive and swift. I loved everything about the entire building and neighborhood. Definitely going back!!
Quick stats about apartment rentals in Clayton
Total rentals
20 properties
Nightly prices starting at
$77 AUD before taxes and fees
Total number of reviews
950 reviews
Family-friendly rentals
10 properties are a good fit for families
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wi-Fi availability
20 properties include access to Wi-Fi
Destinations to explore
- St. Louis Holiday rentals
- Springfield Holiday rentals
- Saint Charles Holiday rentals
- Hermann Holiday rentals
- Innsbrook Holiday rentals
- Jefferson City Holiday rentals
- Dolomiten Holiday rentals
- Grafton Holiday rentals
- Rolla Holiday rentals
- Carbondale Holiday rentals
- Nashville Holiday rentals
- Chicago Holiday rentals
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Busch Stadium
- Enterprise Center
- Six Flags St. Louis
- Saint Louis Zoo
- Central West End
- Gateway Arch National Park
- Missouri Botanical Garden
- St. Louis Aquarium at Union Station
- City Museum
- Saint Louis Science Center
- Hidden Valley Ski Resort
- Castlewood State Park
- Missouri History Museum
- Pere Marquette State Park
- Grafton Winery the Vineyards
- St. Louis Country Club
- Cuivre River State Park
- Adventure Valley Zipline Tours and Paintball Park
- Cathedral Basilica of Saint Louis
- The Winery at Aerie's Resort
- Boone Valley Golf Club
- Raging Rivers WaterPark
- Old Warson Country Club
- Norwood Hills Country Club