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Holiday houses in Chepo

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Chepo

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Apartment in Panama City
4.92 out of 5 average rating, 168 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top Guest favourite
Place to stay in Panama City
5.0 out of 5 average rating, 24 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Top Guest favourite
Boat in San Blas Islands
5.0 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Guest favourite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.97 out of 5 average rating, 88 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Guest favourite
Apartment in San Felipe
4.93 out of 5 average rating, 59 reviews

Colonial style with calicanto and a private balcony

Welcome to a cosy apartment where the charm of the calicanto walls blends with warm details and a perfect balcony to enjoy the atmosphere and the view of the Old Town. We are in a prime location on one of the main avenues of the Casco. From here, you can easily access historical sites, restaurants, cafes, bars and charming spots. The idea is for you to arrive, feel comfortable and enjoy the city at your own pace, whether you're alone, with your partner or with your family.

Top Guest favourite
Guest suite in Panama City
4.97 out of 5 average rating, 110 reviews

Late check-in • Solo or groups up to 6 •Shuttle

✈️ Spacious apartment just 10 minutes from Tocumen Airport. Perfect for layovers, early flights, late arrivals, families, and groups of up to 6 guests. 🛏️ Comfortable beds ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot water 🍽️ Fully equipped kitchen 🚐 Airport transportation available 🔐 Easy check-in with step-by-step instructions 🚗 Safe gated community 📍 Great location for layovers, San Blas tours, and short stays. 💬 Fast communication before and during your stay.

Top Guest favourite
An outdoor area features a modern pool bordered by a sleek railing, with views of surrounding greenery. A cozy seating arrangement is displayed with potted plants, while at night, the property is softly illuminated, highlighting the welcoming entrance and contemporary architecture.
Cabin in Panama City
4.89 out of 5 average rating, 74 reviews

Majestic Cabin in the Mountains

Relax with the whole family at this peaceful place to stay. The majestic Villa Arcoiris is a special place located in an exclusive residential area, with 24/7 security, Los Altos de Cerro Azul. A place within Chagres National Park surrounded by rivers, lakes, waterfalls, trails, and endless wildlife species, where you can experience a different adventure every day. Located 55 minutes from the city and 30 minutes from Tocumen International Airport :)

Guest favourite
Cabin in Panama City
4.93 out of 5 average rating, 92 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Top Guest favourite
Cottage in Panama City
4.95 out of 5 average rating, 40 reviews

Cerro Azul Mountain Retreat a magical home.

Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac

Guest favourite
An outdoor balcony is depicted, offering a panoramic view of the coastline and lush greenery. A small table and chair are visible, providing a comfortable spot to enjoy the scenery. The sky is partly cloudy, casting soft light over the landscape.
Apartment in Panama City
4.95 out of 5 average rating, 37 reviews

07D Great Value Luxury Resort Beachfront Oceanview

Casa Bonita is a one-of-a-kind luxury residence tower in Playa Bonita Village, sitting on the only beach near Panama City and on the same property as a 5 Star private Beach Club resort. Swim in our rooftop pool, workout in the gym, enjoy a massage, stroll on the private beach, play pickleball, enjoy a 5-star restaurant or local cuisine! This spectacular condo will literally take your breath away.

Guest favourite
A modern cabin is nestled among tall pine trees, featuring a sleek black exterior and a pitched roof. The entrance is illuminated, welcoming guests. A gravel path leads to the cabin, bordered by natural wood mulch, creating a serene environment.
Cabin in Panama City
5.0 out of 5 average rating, 16 reviews

Tiny Cabin | Cerro Azul - Cabin I

If you thought Pinterest cabins didn't exist, it's because you haven't been here! Pizza ovens, BBQ area, hammock area, hammock bed, incredible sunsets, views of Lake Alajuela, pine trees, and a cool climate that will make you feel like you've traveled to another country (and we haven't even mentioned all the trails, rivers, and waterfalls you can visit). Check out the photos and enjoy!

Superhost
Home in Panama City
4.92 out of 5 average rating, 12 reviews

Casa Blanca - Private pool, minutes from the city

White House · by Monova Modern house among pine trees, designed to disconnect and breathe. Clean design, large windows and private pool surrounded by nature. Bright spaces, visual balance and real calm. Ideal for couples or families seeking rest, comfort and aesthetics in a safe and exclusive environment. Only 45 minutes from the city, with the peace that is not found in it.

Popular amenities for Chepo holiday rentals