
Guesthouse holiday rentals in Alachua County
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Top-rated Guesthouses in Alachua County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
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Popular amenities for Alachua County guesthouses
Family-Friendly guesthouses

King room at Pareners Branch Creek Guesthouse
This place was a perfect getaway for us. The pool area is amazing and so relaxing. My family enjoyed the pickleball and basketball. The beds were so comfortable and the room was very clean. Jane greeted us and was very friendly and accommodating. We would love to visit again.

Sunflower Acres Cottage
This is our second time staying here, and we couldn’t be happier! This place has quickly become one of our favorites, and it tops our list whenever we're in the area. It has such a peaceful vibe and is always so clean. Plus, the interior is just lovely! We really enjoy our time here.

Gator Getaway
A great, cozy place to stay. Its the closest place you will find right next to the Easton Archery Center.

Renovated Private Studio - Walking Distance to UF
I wish every AirBnb was this perfect! A+ all around. Stayed for our son’s graduation from UF. Super convenient, super clean, and modern. Nice touches. Well thought out.

Beautiful Cottage 10 Minute Walk from UF & Stadium
This was a fantastic rental. Quiet, private, very clean. Rich was helpful but not intrusive at all. I'm a light sleeper, but the thermostat and window treatments kept the place perfectly cool and dark, and the suite is super quiet. Thr selection of local beers in the fridge and coffee pods were a fantstic touch. Certainly the best airbnb experience I've ever had.

Private bed and bath above detached garage.
Great place to stay! Micanopy is a really cute little town as well. I can see how it would be difficult to find at night - as others have stated, go by the instructions not the GPS and it’s pretty straightforward.
Guesthouses with a patio

Millhopper Modern near UF&Shands
We loved staying here! It was exactly as described, the communication was great and they had everything you could possibly need for your stay. We would highly recommend and definitely stay here again next time we are in Gainesville!! 10+ stars⭐️

Private Detached Pool House With Kitchenette
Our host, Glenn, was excellent and very accommodating. He provided everything we needed for a quick getaway. Provided recommendations in the area for us to explore and he was very responsive. We will definitely stay here again if we are in area!

The house of smiles.
Great stay! Angela is very responsive and fixed and issue with the tv/internet. Thanks Angela!

Horning’s Guest House -room for 14
Stayed here for a day trip and this place was so nice!! The owners were so communicative and hospitable, even bringing us eggs, milk, and other condiments, The snow cone machine was so good, and we loved the variety of syrups for coffee! Everyone had a great time and there were more than enough spaces for people to sleep on. Will definitely have to book again😆

Walk to UF! Historic King Bed Loft w/ Private Deck
I had a great stay! The place was clean, comfortable, and exactly as described. The host was easy to communicate with and made check-in super simple. The neighborhood was quiet and felt safe, and everything I needed was close by. Would definitely stay here again!

Our Nest Cute House!
Luis is by far the best host I’ve encountered on Airbnb—kind, helpful, and incredibly responsive. The place was clean, cozy, and quiet, all at a great price. What more could you ask for? Highly recommended!!

Private entrance guest suite
This unit was very comfortable, clean and quiet!!! We enjoyed our two night stay very much. All of our activities were within 2 miles of this location. I would definitely return if I am ever in this area again.

"Nest" in the Guest House up in the Trees near UF
We had a perfect stay at The Nest. If I could give this home more than 5 stars, I would! Deborah is an extremely responsive host and anticipates her guests' every need. We arrived late in the evening after a long car drive and it was so nice to have snacks and drinks waiting for us upon arrival. The kitchen was fully stocked with fresh condiments and cooking supplies, the bed and pullout couch were both super comfy and the entire home was squeaky clean. The bathroom provided an ample supply of towels and amenities. The office nook was a perfect for a workspace. The location is private and serene surrounding by lush trees. And I can't say enough about the beautiful surrounding gardens, wow! We are very frequent AirBnb travelers and this one truly stands out and raises the bar for any others. Highly recommend! This home is our first choice when coming to Gainesville for all future visits. Thank you Deborah!!
Guest house rentals with a washing machine and dryer

Cozy guest room w/double at Pareners Branch Creek
Super sweet host, and room was incredibly cozy and I was able to feel right at home ear the beautiful Alachua scenery

Downtown Studio - 1/2 Mile from UF Campus
Nice small guest house to stay in, right next to UF. Perfect for our needs.

Mother in Law suite/Apartment @ Staycation
Another fantastic quick stay at this Airbnb in downtown High Springs! The location is unbeatable—just a short walk to great restaurants, shops, and coffee spots, and only a quick drive to the beautiful natural springs. The home was clean, comfortable, and had everything I needed for a relaxing stay. Whether you're here for outdoor adventures or just to enjoy the charming town, this is the perfect place to stay. I’ll definitely be back!

Cedar Guesthouse
The place was just as described and was just a few minutes away from downtown which was very accommodating. Lovely place and lovely host.

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands
Great and clean quick stay! Gabriela made everything super easy and the spot was situated in a nice neighborhood. Would definitely stay there again!

Garden Cottage Sanctuary
By far, the best place I have stayed in Gainesville. The home was lovely and very safe for someone traveling by themselves. Laura was a fantastic host by offering local suggestions and even had a welcome bottle of wine and snacks waiting on me. I will plan my work trips around availability as this is now the only place I want to stay.

Sweetwater Studio, on 5 beautiful acres
This is such a beautiful, peaceful place!
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