Guesthouse holiday rentals in Alachua County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Alachua County guesthouses

Family-Friendly guesthouses

Superhost
Private room in Alachua
4.92 out of 5 average rating, 36 reviews

King room at Pareners Branch Creek Guesthouse

SonjaRating, 5 stars10 months ago
This place was a perfect getaway for us. The pool area is amazing and so relaxing. My family enjoyed the pickleball and basketball. The beds were so comfortable and the room was very clean. Jane greeted us and was very friendly and accommodating. We would love to visit again.
Guest favourite
Guesthouse in Gainesville
4.87 out of 5 average rating, 213 reviews

Sunflower Acres Cottage

SheenaRating, 5 stars3 weeks ago
This is our second time staying here, and we couldn’t be happier! This place has quickly become one of our favorites, and it tops our list whenever we're in the area. It has such a peaceful vibe and is always so clean. Plus, the interior is just lovely! We really enjoy our time here.
Guesthouse in Newberry
4.98 out of 5 average rating, 46 reviews

Gator Getaway

PaulRating, 5 stars24 months ago
A great, cozy place to stay. Its the closest place you will find right next to the Easton Archery Center.
Top Guest favourite
Guesthouse in Gainesville
4.97 out of 5 average rating, 547 reviews

Renovated Private Studio - Walking Distance to UF

PatriciaRating, 5 stars2 days ago
I wish every AirBnb was this perfect! A+ all around. Stayed for our son’s graduation from UF. Super convenient, super clean, and modern. Nice touches. Well thought out.
Top Guest favourite
Guesthouse in Gainesville
4.99 out of 5 average rating, 211 reviews

Beautiful Cottage 10 Minute Walk from UF & Stadium

EvaRating, 5 stars2 weeks ago
This was a fantastic rental. Quiet, private, very clean. Rich was helpful but not intrusive at all. I'm a light sleeper, but the thermostat and window treatments kept the place perfectly cool and dark, and the suite is super quiet. Thr selection of local beers in the fridge and coffee pods were a fantstic touch. Certainly the best airbnb experience I've ever had.
Top Guest favourite
Guesthouse in Micanopy
4.93 out of 5 average rating, 169 reviews

Private bed and bath above detached garage.

Meagan&BlakeRating, 5 stars2 days ago
Great place to stay! Micanopy is a really cute little town as well. I can see how it would be difficult to find at night - as others have stated, go by the instructions not the GPS and it’s pretty straightforward.

Guesthouses with a patio

Top Guest favourite
Guesthouse in Gainesville
4.98 out of 5 average rating, 82 reviews

Millhopper Modern near UF&Shands

StaceyRating, 5 stars2 days ago
We loved staying here! It was exactly as described, the communication was great and they had everything you could possibly need for your stay. We would highly recommend and definitely stay here again next time we are in Gainesville!! 10+ stars⭐️
Guesthouse in High Springs
4.74 out of 5 average rating, 23 reviews

Private Detached Pool House With Kitchenette

BethRating, 5 stars2 days ago
Our host, Glenn, was excellent and very accommodating. He provided everything we needed for a quick getaway. Provided recommendations in the area for us to explore and he was very responsive. We will definitely stay here again if we are in area!
Superhost
Guesthouse in Gainesville
4.83 out of 5 average rating, 46 reviews

The house of smiles.

JanisRating, 5 stars1 week ago
Great stay! Angela is very responsive and fixed and issue with the tv/internet. Thanks Angela!
Guest favourite
Guesthouse in Fort White
4.97 out of 5 average rating, 78 reviews

Horning’s Guest House -room for 14

IvyRating, 5 stars2 weeks ago
Stayed here for a day trip and this place was so nice!! The owners were so communicative and hospitable, even bringing us eggs, milk, and other condiments, The snow cone machine was so good, and we loved the variety of syrups for coffee! Everyone had a great time and there were more than enough spaces for people to sleep on. Will definitely have to book again😆
Top Guest favourite
Guesthouse in Gainesville
4.96 out of 5 average rating, 228 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

ShelbiRating, 5 stars3 days ago
I had a great stay! The place was clean, comfortable, and exactly as described. The host was easy to communicate with and made check-in super simple. The neighborhood was quiet and felt safe, and everything I needed was close by. Would definitely stay here again!
Superhost
Guesthouse in Gainesville
4.65 out of 5 average rating, 20 reviews

Our Nest Cute House!

JingRating, 5 stars1 week ago
Luis is by far the best host I’ve encountered on Airbnb—kind, helpful, and incredibly responsive. The place was clean, cozy, and quiet, all at a great price. What more could you ask for? Highly recommended!!
Guest favourite
Guesthouse in Gainesville
4.88 out of 5 average rating, 34 reviews

Private entrance guest suite

CrystalRating, 5 stars1 day ago
This unit was very comfortable, clean and quiet!!! We enjoyed our two night stay very much. All of our activities were within 2 miles of this location. I would definitely return if I am ever in this area again.
Top Guest favourite
Guesthouse in Gainesville
5 out of 5 average rating, 96 reviews

"Nest" in the Guest House up in the Trees near UF

SophiaRating, 5 stars1 day ago
We had a perfect stay at The Nest. If I could give this home more than 5 stars, I would! Deborah is an extremely responsive host and anticipates her guests' every need. We arrived late in the evening after a long car drive and it was so nice to have snacks and drinks waiting for us upon arrival. The kitchen was fully stocked with fresh condiments and cooking supplies, the bed and pullout couch were both super comfy and the entire home was squeaky clean. The bathroom provided an ample supply of towels and amenities. The office nook was a perfect for a workspace. The location is private and serene surrounding by lush trees. And I can't say enough about the beautiful surrounding gardens, wow! We are very frequent AirBnb travelers and this one truly stands out and raises the bar for any others. Highly recommend! This home is our first choice when coming to Gainesville for all future visits. Thank you Deborah!!

Guest house rentals with a washing machine and dryer

Guest favourite
Private room in Alachua
4.97 out of 5 average rating, 33 reviews

Cozy guest room w/double at Pareners Branch Creek

EsmeraldaRating, 5 stars2 months ago
Super sweet host, and room was incredibly cozy and I was able to feel right at home ear the beautiful Alachua scenery
Guest favourite
Guesthouse in Gainesville
4.9 out of 5 average rating, 223 reviews

Downtown Studio - 1/2 Mile from UF Campus

ZacharyRating, 5 stars1 month ago
Nice small guest house to stay in, right next to UF. Perfect for our needs.
Guest favourite
Guesthouse in High Springs
4.83 out of 5 average rating, 12 reviews

Mother in Law suite/Apartment @ Staycation

AntonioRating, 5 stars2 months ago
Another fantastic quick stay at this Airbnb in downtown High Springs! The location is unbeatable—just a short walk to great restaurants, shops, and coffee spots, and only a quick drive to the beautiful natural springs. The home was clean, comfortable, and had everything I needed for a relaxing stay. Whether you're here for outdoor adventures or just to enjoy the charming town, this is the perfect place to stay. I’ll definitely be back!
Guest favourite
Guesthouse in Gainesville
4.84 out of 5 average rating, 51 reviews

Cedar Guesthouse

HermioneRating, 5 stars1 week ago
The place was just as described and was just a few minutes away from downtown which was very accommodating. Lovely place and lovely host.
Top Guest favourite
Guesthouse in Gainesville
5 out of 5 average rating, 7 reviews

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands

PaulRating, 5 stars5 days ago
Great and clean quick stay! Gabriela made everything super easy and the spot was situated in a nice neighborhood. Would definitely stay there again!
Top Guest favourite
Guesthouse in Gainesville
5 out of 5 average rating, 75 reviews

Garden Cottage Sanctuary

ShannonRating, 5 stars1 week ago
By far, the best place I have stayed in Gainesville. The home was lovely and very safe for someone traveling by themselves. Laura was a fantastic host by offering local suggestions and even had a welcome bottle of wine and snacks waiting on me. I will plan my work trips around availability as this is now the only place I want to stay.
Guest favourite
Guesthouse in Alachua
4.97 out of 5 average rating, 29 reviews

Sweetwater Studio, on 5 beautiful acres

PagetRating, 5 stars3 months ago
This is such a beautiful, peaceful place!

Destinations to explore