
Holiday houses in Santo Domingo
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santo Domingo
Guests agree: these stays are highly rated for location, cleanliness and more.

La Caracola: rooftop apartment with jacuzzi near nightlife
PLEASE READ: This charming airbnb is located just steps away from the best nightlife in old Santo Domingo. Every week, from Wednesday to Sunday, both travelers and locals come to our lively street to enjoy the best bars and clubs in the area. If you are interested in exploring this vibrant scene, congrats, you have found the perfect place! If clubbing is not for you, the good news is you can still visit us but we highly recommend booking only during quiet nights: Monday To Wednesday.
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169 5-star reviews, pool/2 jacuzzis/gym
I invite you to immerse yourself in the charm and comfort of this cozy accommodation in the heart of Santo Domingo, steps from the main shopping malls and restaurants. Here you will enjoy a unique and memorable hosting experience. In addition, your safety is our priority, with 24/7 surveillance and staff in the lobby always available. As your Airbnb host, I am committed to making your visit unforgettable and full of amenities. Welcome to your home away from home!
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Garden House
A botanical oasis in the heart of the Zona Colonial. A lush tropical courtyard, surrounded by an extraordinary collection of plants, creates an atmosphere of tranquillity that is hard to find in the city. As an added bonus, guests can enjoy a small shared whirlpool, perfectly integrated into this oasis of greenery. Just a short walk from historic buildings, museums, restaurants and cafés. It will be a real experience in a vibrant area of Santo Domingo.
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Luxurious Rooftop Lounge ♥ Ocean View ♥
From top to bottom, I am offering a luxury experience. • Amazing walking score of 95 (daily errands accomplished on foot) • 270° views from rooftop lounge, bar, and outdoor shower • Onsite washer + dryer. • Redundant fast dual WiFi throughout (5 APs) • Netflix, Hulu, bluetooth soundbars for playing music • We're green... most of our power comes from our solar panels! • Clean drinkable water through RO filter in kitchen and roof bar • Hablamos español
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Loft: Nature in the center with private terrace
The modern design loft is located on the second floor of a French designer house with a separate entrance and private terrace minutes from Mirador Sur Park in a central, residential, and quiet area of Santo Domingo. With a harmonious fusion of urban and natural. Large windows that allow natural light to bathe the space, highlighting earthy tones and vibrant greens. The loft with its own terrace is a charming escape in the heart of the city.
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Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.
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Modern and luxurious beachfront studio
Discover this luxury oceanfront studio, with a panoramic view that you can enjoy from any corner of the space. Live an experience of total privacy, no constructions at the front, just the infinite blue of the Caribbean Sea. A few minutes from Av. George Washington, with quick access to Santo Domingo's main thoroughfares. Ideal for rest, disconnect, work or enjoy a romantic getaway with comfort, elegance and peace in front of the sea.
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Casa Aurelia + Pool + Sleeps 4
Set in the heart of the Zona Colonial, this beautifully restored 17th-century home blends authentic colonial architecture with a fresh, modern feel. Domus Santa Bárbara features five thoughtfully designed apartments surrounding a stunning pool, reserved exclusively for our guests. Enjoy an unforgettable stay in a space where heritage meets modern living—ideal for relaxing, unwinding, and creating memorable moments together.
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Luxury Designer Apartment 2BR Prime Santo Domingo
Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.
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Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.
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Modern Apartment with Rooftop Pool & Ocean Views
Enjoy a comfortable stay in this modern apartment in La Julia, one of Santo Domingo’s most convenient areas. Bright and well-designed, it features a cozy bedroom, full equipped kitchen, and inviting living space. Relax at the rooftop pool with ocean and city views. Located minutes from restaurants, supermarkets, and main avenues—perfect for short or extended stays.
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Loft Best Stay Colonial Zone Hot Water fast wifi
You will feel in a comfortable, safe and warm environment, surrounded by elegance and above all concerned about disinfecting and sanitizing each area and element. Your health is paramount to us. The Loft suits any reason for your trip, whether for vacation or work. we have a power generator too incase the power goes out and it works with the ac too.
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Popular amenities for Santo Domingo holiday rentals
Other great holiday rentals in Santo Domingo

La Casa de Juanchy - Colonial Villa with Private Pool
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Lux Colonial Penthouse w/ priv. terrace & jacuzzi
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Modern apartment in the Colonial City
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Lux 2-Level Townhouse with Stunning Historic Views
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Elegant suite with ocean view and private hot tub
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Easy access and comfort | King-size bed | @DTSD
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Luxury Penthouse with private Jacuzzi/Rooftop
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Casa del Pozo
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