
House holiday rentals in Santo Domingo De Guzmán
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo De Guzmán
Guests agree: These houses are highly rated for location, cleanliness and more.

Entire Home with Pool, Backyard, Security & More!
Beautiful home villa styled that combines comfort and privacy. Perfect for families, couples, or groups of friends, this home is designed for unforgettable moments. Hot water available and visitors allowed! Only minutes away from the SDQ airport, beaches, retail stores, banks, malls, restaurants, bars & clubs. High-class pool with spacious patio furniture set, gather in the fully equipped entertainment room for movie or game nights. The bonus flex space adds extra comfort for additional guests

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Casa Grullon - Loft. Comfort & ancient beauty meet
Perfect, lovely & charming loft to explore La Zona. Transport yourself to another era staying at Casa Grullon Loft (1 master bedroom, 1 open bedroom, 1 bathroom) dating back to the 1700s, offers a unique chance to experience colonial charm without sacrificing modern conveniences (like air-conditioning). Stay here and discover La Zona just by walking! everything is within walking distance (top restaurants are just 1 min away!), making the location perfect to explore the best of Santo Domingo.

casa bella 3 camas 1 king + 2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

La Casita de Gazcue Suit C Luminoso
Este alojamiento sencillo pero encantador te ofrece una experiencia relajante en una ubicación privilegiada: a solo 12 minutos caminando de la histórica Zona Colonial y a tres cuadras del emblemático Malecón, donde podrás disfrutar de vistas al mar, restaurantes, y vida nocturna. Ideal para descansar sin alejarse, nuestro espacio combina serenidad con acceso rápido a los principales puntos turísticos, culturales y gastronómicos. Tu comodidad es nuestra prioridad.

Lugar acogedor, céntrico y bien equipado
Estamos ubicados en un sector céntrico y tranquilo de la ciudad, con acceso a las avenidas 27 de Febrero, Máximo Gómez, Jhon F. kenndy. Contando en la cercanía con la Universidad Iberoamericana (Uníbe), centro comercial Zambil, Torre Banco Popular Dominicano, así como farmacias y centros de salud. El apartamento esta ubicado en un primer piso, con acceso independiente, parqueo y portón eléctrico. Cuenta con sistema de cable, WiFi con alta velocidad, inversor.

Acogedora Casita en el Corazón de la Zona Colonial
Acogedora casa de 2 habitaciones con capacidad para 4 personas, ubicada en el corazón de la Zona Colonial en Santo Domingo a poca distancia a pie de todas las atracciones culturales y turísticas. Cuenta con 2 cómodas habitaciones y un estudio con sofá cama; 2 baños, una linda sala, amplio comedor, cocina equipada y un hermoso patio interior. Maravilloso para vacaciones y viajes culturales, ideal para parejas, familias, amigos y viajeros de negocios .

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Heart of the colonial zone, Billini 54
At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.

El riconcito colonial.
Relájate en este espacio tan tranquilo y elegante como es el rinconcito colonial en el mismo casco historico de la ciudad, un espacio unico, a poco minutos del conde, la catedral, el altar de la patria y centros culturales. Rodeado de numeros restaurantes y zona de ocio y a unos 25 minutos de las playas de boca chica y juan dolio.
Popular amenities for Santo Domingo De Guzmán house rentals
House rentals with a pool

Casa para grupos con Piscina SDE

PrivatePool - BBQ - Terrace - Excelent for Big Fam

Experience Ultimate Comfort | 4BR Home

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Modern Oasis Renovated Home with Private Picuzzi

Villa Royal Con Piscina En Villa mella SD Norte.

• City Oasis • Luminous House nr Colonial Zone

Atypical beachy vibes house, ciudad colonial
Weekly house rentals

Dulce hogar, 3 A/C, 3 Parqueos. Av. Jacobo Mujluta

Estancia cerca del aeropuerto

Historical House.Near Zona Colonial

Cozy & Beautiful City Center House with Jacuzzi

Casa rentada completa picuzzi privado

Sweet 🏡 home

huge luxury two story private residential house

“Tu hogar lejos de casa”
Private house rentals

confortable Casa en Sto Dgo Este

D3Freeee:DesayunoFullWifiNetflix+ComfortBed..

Gran Casa Colonial•Centrico•Amplio •Comodo •Seguro

Casa con excelente ubicación

Casa de Bendición a 20 minutos del aeropuerto

Casa lujosa

Luxury Home con Jacuzzi privado y piscina

Portes 58, Zona Colonial
Quick stats about house rentals in Santo Domingo De Guzmán
Total rentals
500 properties
Nightly prices starting at
$15 AUD before taxes and fees
Total number of reviews
12K reviews
Family-friendly rentals
210 properties are a good fit for families
Pet-friendly rentals
130 properties allow pets
Rentals with a pool
100 properties have a pool
Destinations to explore
- Punta Cana Holiday rentals
- San Juan Holiday rentals
- Las Terrenas Holiday rentals
- Santiago De Los Caballeros Holiday rentals
- Santo Domingo Este Holiday rentals
- Puerto Plata Holiday rentals
- Sosúa Holiday rentals
- La Romana Holiday rentals
- Cabarete Holiday rentals
- Bayahibe Holiday rentals
- Juan Dolio Holiday rentals
- Carolina Holiday rentals
- Loft rentals Santo Domingo De Guzmán
- Beachfront rentals Santo Domingo De Guzmán
- Family-friendly rentals Santo Domingo De Guzmán
- Rentals with pools Santo Domingo De Guzmán
- Guesthouse rentals Santo Domingo De Guzmán
- Serviced apartment rentals Santo Domingo De Guzmán
- Ski-in/ski-out rentals Santo Domingo De Guzmán
- Apartment rentals Santo Domingo De Guzmán
- Condo rentals Santo Domingo De Guzmán
- Rentals with a fire pit Santo Domingo De Guzmán
- Rentals with a washing machine and dryer Santo Domingo De Guzmán
- Rentals with an EV charger Santo Domingo De Guzmán
- Hotel rentals Santo Domingo De Guzmán
- Rentals with a hot tub Santo Domingo De Guzmán
- Aparthotel rentals Santo Domingo De Guzmán
- Rentals with a fireplace Santo Domingo De Guzmán
- Fitness-friendly rentals Santo Domingo De Guzmán
- Mansion rentals Santo Domingo De Guzmán
- Rentals with a sauna Santo Domingo De Guzmán
- Rentals with breakfast Santo Domingo De Guzmán
- Pet-friendly rentals Santo Domingo De Guzmán
- Rentals with outdoor seating Santo Domingo De Guzmán
- Waterfront rentals Santo Domingo De Guzmán
- Rentals with a home theatre Santo Domingo De Guzmán
- Rentals with a patio Santo Domingo De Guzmán
- Smoking-friendly rentals Santo Domingo De Guzmán
- Rentals with an accessible height bed Santo Domingo De Guzmán
- Villa rentals Santo Domingo De Guzmán
- Rentals with lake access Santo Domingo De Guzmán
- Bed and breakfasts Santo Domingo De Guzmán
- Rentals with beach access Santo Domingo De Guzmán
- House rentals Distrito Nacional
- House rentals Dominican Republic
- Things to do Santo Domingo De Guzmán
- Nature and outdoors Santo Domingo De Guzmán
- Art and culture Santo Domingo De Guzmán
- Things to do Distrito Nacional
- Food and drink Distrito Nacional
- Nature and outdoors Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Nature and outdoors Dominican Republic
- Sightseeing Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Food and drink Dominican Republic
- Art and culture Dominican Republic