
Mansion holiday rentals in Santo Domingo
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Top-rated mansion rentals in Santo Domingo
Guests agree: These mansions are highly rated for location, cleanliness and more.

Beautiful Modern Penthouse close to Zona Colonial.
Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 5 smart TVs and much more. Smart lock for easy check-in.
4.88 out of 5 average rating, 197 reviews
Casa Pantheon Luxury Colonial House
Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED
4.94 out of 5 average rating, 386 reviews
Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.
4.99 out of 5 average rating, 147 reviews
Eclectic,Spacious,4BR Penthouse
Air conditioner is fixed in the living room! Completely renovated Colonial Apartment-Penthouse on Famous El Conde St . in the heart of Zona Colonial. M-lily Mattresses ,Luxury Bedding Lacoste , CK ,RL Brand new Fully equipped Chef Kitchen with top brands cooking tools Self check-in Laundry&market service available Gym next door , day pass $2 Safest location Politur HQ across street Shampoo &bodywash Bright,Airy,Fresh Latest tech lighting crib XLL Balcony 24/7 electric kit
4.88 out of 5 average rating, 104 reviews
Casa del Orfebre, circa 1525
Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.
4.95 out of 5 average rating, 44 reviews
VillaRosario-Resort-Poolhothub NearAirport & Beach
Escape to our luxurious tropical villa in Santo Domingo Este, Samana Road, Dominican Republic! Ideal for families, friends, and gatherings, this spacious retreat features 6 bedrooms, 12 beds, and 3 floors, cozy ambient lighting. Step outside and immerse yourself in a lush paradise, enjoy organic delights from the fruit garden, and relax by the private pool with a relaxing waterfall and Jacuzzi. Sports enthusiasts will love the private basketball court.
4.85 out of 5 average rating, 109 reviews
Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.
5.0 out of 5 average rating, 61 reviews
Paradise Luxury Penthouse With Private Jacuzzi
Comfortable and clean apartment in a safe area. Located on Avenida España. Just 20 minutes from the airport, 25 minutes from Boca Chica beach, and 15 minutes from the colonial zone. It has multiple options of restaurants, bars, mixers, supermarket, pharmacies, bodegas or grocery stores and more just minutes away. Air conditioning in each bedroom as long as there is electricity, if not we have fans powered by an inverter.
4.89 out of 5 average rating, 240 reviews
Spacious house, gated community of Alma Rosa I
This house is located in a closed and very safe residential area. It is centrally located; only 20 minutes from the airport of Las Americas and a few minutes from the most iconic places in the great Santo Domingo. You can also walk to the restaurants, supermarket and shopping centres in the area. We offer check- in early and late check-out, according to the reservations we have pending.
4.81 out of 5 average rating, 136 reviews
Luxury Villa with private Pool, swim Bar, Jacuzzi+
Luxury Villa with Pool, Jacuzzi, Swimup Bar, Fast WiFi, A/C, Chef's Kitchen, EV Charger, 4 Car Private Parking Peaceful, stylish & spacious 5BR/5BA villa in central Vista Hermosa 🌴 Unique & family-friendly, sleeps 13 🛏️ (4 King, 2 Queen, 1 Twin). A/C throughout ❄️, 3 ensuite rooms, minutes from airport ✈️, malls 🛍️, restaurants 🍽️ & attractions 🌆. Your private paradise awaits!
4.89 out of 5 average rating, 27 reviews
Penthouse 5BR | Billar | City View | Terrace Top
Experience a modern 3-level penthouse in the heart of Evaristo Morales. With 5 bedrooms, spacious living areas, a private terrace, and elegant design, it’s ideal for families and groups. Steps from Gold’s Gym, Smart Fit, supermarkets, restaurants, and banks, and minutes from BlueMall, Acropolis, and Ágora Mall. Enjoy comfort, style, and the best location in Santo Domingo.
4.86 out of 5 average rating, 124 reviews
Villa Francisco RD, (15min Airport) Chef Included.
Do you want to disconnect and enjoy nature? This modern, welcoming apartment is ideal for a weekend with the whole family and will make you feel at home. Enjoy one of the best outdoor spaces by the pool, where you can prepare a delicious barbecue while relaxing and soaking up the sun. 15 minutes from Aeropuerto de las Americas (airport) and 12 minutes from downtown.
4.88 out of 5 average rating, 136 reviewsPopular amenities for Santo Domingo mansion rentals
Luxury mansion rentals

Domus Santa Barbara Pool House Sleeps 12
5.0 out of 5 average rating, 7 reviews
Bella Vista Luxury Penthouse for 19 w/ Jacuzz XL
5.0 out of 5 average rating, 4 reviews
Atypical pool house, ciudad colonial
4.95 out of 5 average rating, 97 reviews
✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL
4.8 out of 5 average rating, 74 reviews
FIXIE Lofts: Elegant Colonial Villa with Pool
4.77 out of 5 average rating, 13 reviews
® {Acqualina's ~ Views} @ DowntownSD + 4BR Penthouse + Pool
4.83 out of 5 average rating, 40 reviews
Casa RossAmor
4.75 out of 5 average rating, 140 reviews
Villa Alcántara Luxury-Private Pool Modern Design
5.0 out of 5 average rating, 6 reviewsPet-friendly mansion rentals

'Casa de Papel' Luxurious Villa
4.85 out of 5 average rating, 47 reviews
House in the city with an oceanfront swimming pool
4.92 out of 5 average rating, 12 reviews
Luxury Penthouse With Jacuzzi
4.95 out of 5 average rating, 95 reviews
Luxury Penthouse in Santo Domingo
4.77 out of 5 average rating, 73 reviews
Bonita villa RD
4.77 out of 5 average rating, 30 reviews
villa yaya
4.96 out of 5 average rating, 25 reviews
Spacious 4BR pool house with private parking
4.53 out of 5 average rating, 34 reviews
Penthouse with Private Terrace Pool overlooking the Sea
4.62 out of 5 average rating, 13 reviewsMansion rentals with a pool

Experience Ultimate Comfort | 4BR Home
4.82 out of 5 average rating, 60 reviews
Spacious villa, Van & driver available
4.75 out of 5 average rating, 52 reviews
Luxurious house with pool
4.71 out of 5 average rating, 51 reviews
Spacious Villa for large groups with Private Pool
4.71 out of 5 average rating, 106 reviews
Pool + Family Comfort
5.0 out of 5 average rating, 15 reviews
Comfortable and complete apartment
4.77 out of 5 average rating, 13 reviews
Beverly Hills Residencíal
4.62 out of 5 average rating, 94 reviews
House for groups with a pool SDE
4.85 out of 5 average rating, 34 reviewsDestinations to explore
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- Mansion rentals Dominican Republic
- Playa Nueva Romana
- Ciudad Juan Bosch
- Malecón
- Metro Country Club
- Playa Guayacanes
- Blue Mall
- Megacentro
- Playa Hemingway
- Downtown Center
- Agora Mall
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- Dr. Rafael Ma. Moscoso National Botanical Garden
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