
Mansion holiday rentals in Santo Domingo
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Santo Domingo
Guests agree: These mansions are highly rated for location, cleanliness and more.

Casa Pantheon Luxury Colonial House
Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED
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Beautiful Modern Penthouse close to Zona Colonial.
Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 4 smart TVs and much more. Smart lock for easy check-in.
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Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.
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Luxury Penthouse With Jacuzzi
Come and decompress into your private oasis retreat. This penthouse features 4 bedroom, 3 bath, fully equipped kitchen, and calming jacuzzi. Immerse yourself in panoramic views from rooftop terrace. We are located in one of the best residential area in Santo Domingo Este. Just 15 min. from Las America International Airport, and 20 min. from beaches. Nearby you will also find great restaurants, bars, supermarket, shopping centers and pharmacies. Book now for the utmost Dominican Experience!!
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VillaRosario-Resort-Pool-Wifi-BBQ-NearBeach-Relax
¡Escápate a nuestra lujosa villa tropical en Santo Domingo Este carretera Samana , República Dominicana! Ideal para familias, amigos y reuniones, este amplio refugio cuenta con 6 habitaciones, 12 camas y 3 piso, acogedora iluminación ambiental. Sal al exterior y sumérgete en un paraíso exuberante, disfruta de delicias orgánicas del jardín de frutas y relájate junto a la piscina privada con una relajante cascada y jacuzzi. Los entusiastas del deporte adorarán la cancha de baloncesto privada.
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Casa del Orfebre, circa 1525
Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.
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Luxury Rooftop Penthouse|Chef Experience|Sleeps 10
Indulge in a luxury rooftop lifestyle with this stunning penthouse, complete with a private jacuzzi, lounge, and panoramic city views. Elevate your stay with a private chef experience available upon request, creating unforgettable dining moments in total privacy. Ideal for families and groups, this expansive residence comfortably accommodates up to 10 guests while maintaining privacy, elegance, and high standards Note: Private chef service must be arranged in advance.
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Luxe 4 Bedrooms, Pool, King Beds
Bring the whole family to this great place with lots of room. This 4 bedroom apartment great for large groups including two king beds. The location of this apartment in one of the most centrally located and exclusive areas in Santo Domingo is reason enough to want to be there, not to mention the exquisite decoration Furthermore the tower with all modern amenities including a pool, gym, and much more making it the perfect choice for you.
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Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.
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Paradise Luxury Penthouse With Private Jacuzzi
Apartamento cómodo y limpio en una area segura. Ubicado en la avenida España. A solo 20 minutos del aeropuerto, 25 minutos de la playa boca chica y 15 mins de la zona colonial. Cuenta con multiple opciones de restaurantes, bars, mixers, supermercado, farmacias, bodegas o colmados y mas a solo minutos. Aire acondicionado en cada dormitorio siempre que haya energía eléctrica, de no haber contamos con abanicos movidos por un inversor.
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Beautiful and comfortable house in the Colonial City
Te ofrecemos una magnífica estadía en este alojamiento de la Ciudad Colonial. La casa además de hermosa, tiene muchos espacios para pasarla bien y sentirte cómodo. Ven y disfruta de nuestra piscina que te refrescará del calor caribeño. Las calles de la Ciudad Colonial están siendo reparadas ahora mismo, pero esto no impedirá que tu estancia sea magnífica. *La casa no cuenta con parqueo* *La piscina no tiene calefacción *
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Penthouse | Top View | Jacuzzi | Near BlueMall
Modern 3-level penthouse with 5 bedrooms, 7 beds and panoramic city views. Located in Evaristo Morales, walking distance to Gold’s Gym, Smart Fit, supermarkets, restaurants and BlueMall/Acropolis. Perfect for families and groups, offering spacious social areas, balconies, fast WiFi and private parking. Minutes from main attractions like Mirador Sur, Parque Iberoamérica and the best dining spots in Santo Domingo.
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Popular amenities for Santo Domingo mansion rentals
Luxury mansion rentals

8-Bedroom Penthouse: Jacuzzi, Pool Table, Terrace
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Villa Sabrina
LocationFamilyBarbecue

7 Rooms/Beds and 1 Sofa Bed. Free Breakfast
CleanlinessBreakfastAccuracy

Domus Santa Barbara Pool House Sleeps 12
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Luxury Villa with private Pool, swim Bar, Jacuzzi+
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FIXIE Lofts: Elegant Colonial Villa with Pool
LocationFamilyHospitality

✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL
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® {Acqualina's ~ Views} @ DowntownSD + 4BR Penthouse + Pool
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Pet-friendly mansion rentals

Hacienda Moreyca 26 guests Pool BBQ Billiards
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villa yaya
LocationFamilyComfort

Bonita villa RD
LocationFamilyBarbecue

Spacious 4BR pool house with private parking
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White House Villa Santo Domingo
LocationFamilyWi-Fi

Villa oasis
LocationValueOutdoor spaces

Apartment with ocean view Av. España, esplanade
LocationHospitalityLong stay

Villa Ana Cristina
ValueFamilyPool
Mansion rentals with a pool

Beverly Hills Residencíal
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Casa Erzulie - Enjoy the colonial city
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House for groups with a pool SDE
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Penthouse with Private Terrace Pool overlooking the Sea
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Experience Ultimate Comfort | 4BR Home
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Comfortable and complete apartment
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Luxurious house with pool
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Villa Flor, Las Americas
ValueFamilyAir conditioning
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- Mansion rentals Dominican Republic
- Playa Nueva Romana
- Ciudad Juan Bosch
- Metro Country Club
- Malecón
- Playa Guayacanes
- Blue Mall
- Playa Hemingway
- Downtown Center
- Teatro Nacional Eduardo Brito
- Zona Colonial
- Megacentro
- Agora Mall
- Galería 360
- Bella Vista Mall
- Parque Iberoamerica
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Cathedral of Santa María la Menor
- Juan Dolio
- Playa Caribe
- Columbus Park
- The 3 Eyes National Park
- Casa De Teatro
- Columbus Lighthouse
- Museum of the Royal Houses
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