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Holiday houses in Santa Fe

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Fe

Guests agree: these stays are highly rated for location, cleanliness and more.

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Apartment in Santa Fe
4.67 out of 5 average rating, 3 reviews

LaQhia Casa Loros 5

This Panamanium adventure begins nestled in the greenery of a lush rainforest near SantaFe National Park.Your private apartment secluded from the world offers warm air&the scent of greenery&orchids.Sounds of the jungle/tropical birds call daily. LaQhia Eco Retreat has Cayucos Bar/Restaurant.Also a mind body yoga shala offers otehr services.** fees apply Deeper into the rainforest discover hidden cascading waterfalls.Soak in the beauty&relax with nature. *Refer to house manual for more amenities.

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Home in Santa Fe
4.8 out of 5 average rating, 5 reviews

Orange Corner Cottage

Welcome to our centrally located, newly renovated home within the village of Santa Fe. Easy walking distance to the bus terminal, restaurants, cafes, grocery stores and artisanal markets. Enjoy a hot shower, Starlink Wi-Fi and the easy access, central location. Santa Fe now has a new asphalt road from Santiago as well as a fuel station and various ATMs. Please note, all centrally located accommodations in Santa Fe are affected by general noise, especially over the weekends and holidays.

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A modern cabin with a unique architectural design is showcased, featuring an orange and stone exterior. A covered porch area provides shelter and views of the surrounding greenery. A gray vehicle is parked in front, illustrating easy access to this welcoming space.
Cabin in Santa Fe
4.65 out of 5 average rating, 17 reviews

Rincon de Cielo Cabin

Enjoy nature and a stylish experience in this accommodation located in downtown Santa Fe and close to rivers, waterfalls and mountains. The property has beautiful views of the mountains and a small lake. The property can accommodate more than two guests upon coordination and for an additional price per person. The cabin is elegant and has a room with A/C, laundry, kitchen and living/dining room. Use of the kitchen and laundry has an additional cost of $10.00

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A modern cabin is set within a serene forest of towering pine trees. The structure features a light-colored exterior with a red metal roof and a combination of stone and textured walls. Natural light filters through the windows, enhancing the peaceful atmosphere.
Cabin in Calobre
4.6 out of 5 average rating, 15 reviews

La Pinea Lodge

Enjoy a pleasant and cozy stay in the Cabin among the Pines. Ideal for those looking for tranquility, comfort and a pleasant stay with family and friends. Located at the entrance of La Yeguada Natural Park, on a large plot of land near natural attractions such as Lago el Flor, Cascada la Furunera and 3 km from the Lagoon. It has basic amenities; in addition to a shower with hot water, good Tigo mobile phone signal, ample parking space.

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Cabin in Santa Fe
5 out of 5 average rating, 4 reviews

Casa Vianka, the best mountain views

¡Bienvenidos a Casa Vianka en Santa Fe, Veraguas! Una espaciosa cabaña ideal para familias o amigos que buscan desconectar en la naturaleza con total comodidad. ¿Por qué elegirnos? • Espacio: 2 amplias habitaciones y 2.5 baños. • Ubicación: Cerca del centro, restaurantes y tiendas. • Aventura: A minutos de los mejores ríos y senderos. Disfruta del clima fresco en este alojamiento tranquilo y céntrico. ¡Reserva hoy y vive Santa Fe!

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A spacious white house is set against a backdrop of lush greenery. The building features large windows and is surrounded by various trees. A gently sloping grassy area leads up to the house, providing an open and serene environment.
Holiday home in Santa Fe
4.55 out of 5 average rating, 29 reviews

A charming place to enjoy with family or friends

Enjoy a spacious house exclusively for you, your family, or group of friends. A place where you will have complete privacy and total tranquility and where you will not have to share the facilities with other guests. Hostal Vernaza is a safe and quiet house, with access to everything (supermarket, pharmacy, health center, church, restaurants, craft market, rivers, trails, waterfalls, mountains, beach and more).

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Guest favourite
Farm stay in Santa Fe
4.9 out of 5 average rating, 327 reviews

Cabin of the Sun in Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

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Guest favourite
Cottage in Santa Fe
4.9 out of 5 average rating, 21 reviews

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

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Guest favourite
A rural house with a terracotta roof is situated among lush greenery, framed by mountains. A vehicle is parked in front, with a natural landscape extending around the property. Whispering trees and distant hills offer a serene background.
Cottage in Santa Fe
4.92 out of 5 average rating, 13 reviews

Country house, La Mismísima

La Mismísima is a magical place to disconnect and live a unique experience in the middle of nature. A spacious place that invites you to meditate, read, have a good coffee with a delicious and special climate for photography lovers. It is a country house with the comforts to make you feel at home, with the tranquility and peace that nature gives you.

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Cabin in Calobre
4.75 out of 5 average rating, 28 reviews

La Yeguada - Forest Point Cabin

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse, totalmente equipada cabaña de campo con cocina amplia, sala de estar con acceso a televisión, hamacas, refrigerador, estufa, agua caliente y todo lo que necesitas para pasar un buen momento alejado del ruido y convivir con la naturaleza.

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Superhost
Apartment in SANTA ANA
New place to stay

Disfruta Casco Viejo en fabuloso rooftop

Disfruta de una experiencia con estilo en este alojamiento céntrico, nuevo, cómodo, con todo lo necesario para una excelente estadía, rooftop para disfrutar el clima, la vista y la brisa de la tarde. En límites del Casco Antiguo pero a minutos caminando a restaurantes, bares y todo lo que ofrece el Casco.

Top Guest favourite
A spacious living area is surrounded by large windows, offering panoramic views of the lush landscape. Comfortable seating is arranged in a circular layout, adorned with colorful cushions. A central coffee table is complemented by decorative plants and a warm wooden floor enhances the inviting ambiance.
Farm stay in Santa Fe
5 out of 5 average rating, 23 reviews

Mansion on Organic Farm with Heated Pool

Capacity 32 people - Relax with the whole family and friends in this cosy house on an organic farm with animals, crops, tilapia fishing and coffee. There are rivers, a heated pool and a 120-metre covered terrace for you to celebrate your special occasions.

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Popular amenities for Santa Fe holiday rentals