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Holiday houses in Santa Cruz County

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Guest suite in Patagonia
4.94 out of 5 average rating, 146 reviews

Box T Studio

Whether you're here for a weekend of hiking, birding, biking, wine tasting, or simply slowing down, the Box T Ranch makes a comfortable home base for any adventure! Just a short walk from downtown Patagonia, the central location makes the Studio ideal for adventures in all directions. Some of the amenities that make the Studio so comfortable include the amazing king size bed, a two person walk in shower, a 57" big screen Sony TV, a mini fridge, a Keurig, and Starlink WiFi. Come visit us today!

Guest favourite
A charming adobe-style guesthouse features a covered porch with seating areas. Natural stone pathways lead to the entrance, flanked by desert landscaping and potted plants. The exterior showcases warm earth tones with a tile roof, surrounded by open skies and a peaceful atmosphere.
Guesthouse in Tubac
4.86 out of 5 average rating, 114 reviews

Amazing Casita at the Tubac Resort-Self check-in*

Take it easy at this unique and tranquil getaway in the beautiful and historic Tubac Golf Resort. Located in a quiet neighborhood just a 5 minute walk to resort amenities including, spa, salon, resort shops, and Stables restaurant. Our Guesthouse includes a king bed, Sofa bed, personal driveway to park your car, private entrance, beautiful terrace, fireplace, Smart TV, internet, coffee maker, microwave, and mini refrigerator. Known as a center of art and history, is truly worth the visit.

Top Guest favourite
A serene landscape features rolling mountains bathed in warm light from a setting sun. The view encompasses lush greenery and a dirt path leading to a guest house nestled among the hills, highlighting a peaceful rural retreat.
Home in Patagonia
5 out of 5 average rating, 38 reviews

Serenity, Starlink and waking up with bird songs

Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

Top Guest favourite
A vibrant sunset casts a spectrum of purples and oranges across the sky, with silhouetted mountain peaks in the distance. The scene is set against a tranquil landscape dotted with sparse trees, showcasing the natural beauty of the surroundings.
Guesthouse in Elgin
4.97 out of 5 average rating, 266 reviews

Cozy Thunder Mountain Ranch bunkhouse experience

The perfect "getaway" that's still "near" it all! Our stand alone southwestern bunkhouse offers comfortable accommodations in a very unique setting, surrounded by thousands of acres of the Coronado National forest. Located in the desirable Sonoita/Elgin area of Southern Arizona. Near Parker Canyon Lake! From just soaking up the quiet serenity for a day or two, to an adventure filled longer stay, we can help tailor your experience to enjoy the many different things to see and do in the area.

Top Guest favourite
Guesthouse in Patagonia
4.99 out of 5 average rating, 110 reviews

Dream House

Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Top Guest favourite
A hammock is gently draped between two trees, with the fabric partially visible in the foreground. The background features a stunning sunset, casting soft hues across the sky. The landscape is open, with sparse vegetation and rolling hills creating a tranquil environment.
Guest suite in Nogales
4.94 out of 5 average rating, 149 reviews

Patagonia Lake Hideaway

PRIVATE SPACE! $105 p nite NO CLEANING FEES but airbnb charges its own fees. king bed, picture window, sofa, french doors,electric fireplace, tv, Private courtyard&patio, sunrise over Patagonias,sunset behind the Atascosas. Birding paradise.part of Madrean sky Island.Lake minutes away with boat rentals, swimming, fishing, hiking, small beach. Easy travel toTombstone, AZ Trail, Tubac, Kartchner caverns, Patagonia, Mexico, wine and spirit tasting .check in whenever.check out 5pm

Top Guest favourite
A refreshing saltwater pool is framed by a spacious deck, lined with comfortable lounge chairs. The surrounding landscape features native plants and offers expansive views of the desert terrain and distant mountains under a dramatic sky.
Cottage in Patagonia
4.97 out of 5 average rating, 132 reviews

Kestrel Cottage at Birdsong Retreat

ATTENTION SUMMER BOOKINGS: Swamp cooler entire cottage and AC wall unit in queen bedroom. We provide fans. With monsoon rains, it’s too humid to use swamp cooler. Cottage priced to reflect the heat. Escape to serene high desert grasslands in Patagonia, AZ, offering 360-degree views at 4,058 feet offering respite from the Phoenix and Tucson heat. Nestled within BirdSong Retreat on 37 acres, the Kestrel Cottage promises luxurious accommodations and a focus on well-being.

Top Guest favourite
The exterior of the apartment features a vibrant yellow adobe wall, accented by a decorative horse motif. A wooden bench sits beneath a window with wrought iron detailing, while potted plants add greenery to the entrance. Rain-soaked surfaces reflect the surrounding colors.
Apartment in Nogales
4.94 out of 5 average rating, 249 reviews

Las Hacienditas Large Two-Bedroom Apartment

Located in the beautiful town of Rio Rico. Just a few minutes from the Mexican border and from the art community at Tubac. A few blocks from a beautiful walking trail, gymnasium and several churches. This private apartment has all the amenities you need for a short or long stay. We take all the necessary steps to make sure the space is sanitary by disinfecting all areas and washing all bedding and linens to protect you and your family or guests.

Top Guest favourite
A Santa Fe style residence is framed by native desert vegetation, including cacti and broader plants. A winding pathway leads toward the whitewashed exterior, partially obscured by trees, enhancing the natural surroundings of the peaceful community.
Home in Tubac
5 out of 5 average rating, 22 reviews

Mesquite Haven

Fantastic home located in a peaceful and beautiful community surrounded by desert nature. This Santa Fe style residence invites you to relax and escape a busy lifestyle while still having access to modern amenities. Enjoy life outdoors in a basically traffic free private community rich with local flora and fauna. The location is great for morning or evening walks or runs, Tubac Resort wedding guests, visits to the village, hiking trips, etc.

Guest favourite
The guesthouse features a cozy sleeping area with a spacious bed dressed in simple linens. A comfortable sofa is positioned next to a wood bookshelf, which holds various decorative items. A desk and chair provide a dedicated workspace, with natural light filtering through the curtains.
Guesthouse in Rio Rico
4.87 out of 5 average rating, 376 reviews

Cozy Rio Rico guesthouse with a view

This spacious guesthouse is in an ideal rural setting. Located near the Mexican border, the art community at Tubac, and the old Spanish mission of Tumacacori, there is lots to see and do. (Not to mention many good golf courses.) I am looking forward to your visit! To make your stay both pleasant and sanitary I steam clean floors, sani-wash all linens and towels, and wipe counters, sinks and toilet with sanitizer spray. Rest easy here!

Top Guest favourite
The home is set under two large oak trees, providing a natural shaded environment. A spacious outdoor area is visible, featuring a patio with seating. Surrounding greenery enhances the serene landscape, while a fenced yard adds to the property's secluded feel.
Cottage in Sonoita
4.96 out of 5 average rating, 224 reviews

Under the Oaks

Escape to the peaceful beauty of Under the Oaks, nestled beneath three magnificent oak trees with sweeping views of rolling grasslands and distant mountains. Relax in the spotless, comfortable home, unwind on the screened porch as the sun sets, or enjoy birdwatching, grilling, and a glass of local wine beneath the spacious ramada. Shady oaks, abundant wildlife, and tranquil surroundings create the perfect Southern Arizona getaway.

Top Guest favourite
A green casita is situated in an open landscape, surrounded by a rustic fence. A gravel driveway leads towards the entrance, with an American flag waving gently overhead. Lush grass and a few scattered trees enhance the rural setting under a clear blue sky.
Home in Sonoita
4.98 out of 5 average rating, 289 reviews

Sky Island Retreat Sonoita, AZ.

Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.

Popular amenities for Santa Cruz County holiday rentals