
House holiday rentals in Santa Cruz County
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Top-rated house rentals in Santa Cruz County
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Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.
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McFitz Guest Ranch
McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake
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Serenity, Starlink and waking up with bird songs
Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.
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Five Ranges Outpost
Escape to the country at Five Ranges Outpost in Sonoita, Arizona. Our 3-bedroom, 2-bathroom retreat offers space to unwind, surrounded by the stunning beauty of five mountain ranges. Situated on nearly 10 acres of pristine land, our property provides a tranquil setting for relaxation and adventure. At roughly 5,000 feet, the Outpost enjoys cooler summer temps. Crisp mornings and warm days give way to dramatic afternoon monsoons, creating the perfect backdrop for your high desert escape.
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Recently Remodeled Patagonia’s Farmhouse
Patagonia is a small town and this home provides a place to relax and recharge. Our house is just a short 20 minute drive to Patagonia Lake gate, Patton's hummingbird center, 4 minute drive or 20 minute walk. We are directly on the Arizona trail within minutes to numerous other hikes! If you keep traveling on Harshaw there are plenty of great ATV trails. You’ll love our place because the views are great and the beds are extremely comfortable. We just completed a remodel in October 2022.
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Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).
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A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!
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Cottage on Santa Rita | Sundrenched 2 bd/1 bth
Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.
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Patagonia's Private Paradise
$100 PER NIGHT SUMMER IN PATAGONIA IS A WONDERFUL TIME SUMMER DISCOUNT READ OUR REVIEWS BEFORE YOU CHOOSE Patagonia is located high in the SKY ISLANDS of Southeast Arizona. The higher elevation and mountain forests make Patagonia much cooler than the Arizona cities at a lower elevation. Come to Patagonia and enjoy great discounts for longer-term stays at a time of year that many find nice and green. 20% OFF FOR 7 NIGHTS OR MORE 35% OFF FOR 28 DAYS OR MORE
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Peaceful Family Friendly + Fire Pit + Volleyball
Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.
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The Somm's Aviary
Welcome to our peaceful home in Sonoita Meadows just off Hwy 83, perfectly situated between the exceptional Sonoita-Elgin wineries and prime birding grounds of Patagonia-Sonoita Creek. Explore by day, then unwind under the stars by a cozy firepit from your private patio. Your getaway awaits! Dual zone wine fridge? Check. Birding binoculars? Check. Outdoor grill? Of course. Plus a 75" TV and board games for the homebody in you.
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Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.
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Popular amenities for Santa Cruz County house rentals
House rentals with a pool

Gallo Libre Ranch House in Arivaca, Arizona
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Beautifully Bewitching Mansion Indoor Pool

Poolside Escape Near Patagonia
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Casa de Anza
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Stylish Townhome, 2BD, 2BA-Pool & Gym Access.
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Cozy 2 bedroom townhouse, Tubac
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Walk to Tubac village and birding/hiking trail!
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Valle Verde Ranch House.
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Weekly house rentals

Cosy House: Two bedroom - great WiFi and RO water
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Quiet, airy home in Nogales, in the hills.
LocationHospitalityIndoor spaces

Cozy stay in wine country at Penelope's Place
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Maria's Retreat - Walking distance to the Resort!
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Camp Cathy
LocationFamilyView

Mesquite Haven
LocationFamilyBarbecue

Tilted Horse Ranch in the heart of wine country
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Ranger Trail Camp
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Private house rentals

Tres Bellotas Ranch Guest House
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Río Rico Retreat

Comfortable and relaxing place
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Modern Elgin Home: Walk to Wineries + Pets Welcome
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YELLOW HOUSE NEAR THE BORDER
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Vince’s Townhome
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Casa Rio Rico
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Fully private casita in heart of town!
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Destinations to explore
- Rentals with a fireplace Santa Cruz County
- Rentals with a patio Santa Cruz County
- Rentals with a washing machine and dryer Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- Rentals with a fire pit Santa Cruz County
- Rentals with pools Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- Apartment rentals Santa Cruz County
- House rentals Arizona
- House rentals United States
- University of Arizona
- University of Arizona
- Saguaro National Park
- Tumamoc Hill
- Arizona-Sonora Desert Museum
- Kartchner Caverns State Park
- Patagonia Lake State Park
- Sabino Canyon Recreation Area
- Tucson Botanical Gardens
- Reid Park Zoo
- Titan Missile Museum
- Tucson Convention Center
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Rialto Theatre
- Children's Museum Tucson
- Sonoita Vineyards
- Mini Time Machine Museum of Miniatures
- Tumacacori National Historical Park
- Trail Dust Town
- Rune Wines
- Mercado San Agustin
- Tubac Presidio State Historic Park





