
House holiday rentals in Santa Cruz County
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz County
Guests agree: These houses are highly rated for location, cleanliness and more.

Modern Elgin Home: Walk to Wineries + Pets Welcome
With its elegant design, secluded location, and 1-bedroom, 1-bath, ‘Starry Night Guest Retreat’ is the perfect cozy vacation rental! Start your days off by relaxing on the patio and admiring the views of the Mustang Mountains. When it’s time to explore, head to Deep Sky Winery for a glass of wine, try out some nearby birdwatching, or enjoy the farm animals grazing the meadow. Finish your stay with a visit to the old town of Tombstone and Kartchner Caverns State Park to see all that Elgin offers!
LocationFamilyAmenities
4.97 out of 5 average rating, 118 reviews
Javelina Corner
Our place is close to Patagonia Lake, 10 minute drive, Patton's hummingbird center, 2 minute drive or 8 minute walk. There is access to the Arizona trail at two locations within 10-20 minute drive and numerous other hikes! Tombstone, Bisbee, The Art haven of Tubac is close by and Nogales Mexico is 19 miles. You’ll love our place because of the neighborhood, the coziness, and the comfy beds. Our place is good for couples, solo adventurers, business travelers, families , and furry friends (pets).
LocationValueBarbecue
4.84 out of 5 average rating, 148 reviews
Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.
ValueFamilyOutdoor spaces
4.86 out of 5 average rating, 119 reviews
McFitz Guest Ranch
McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake
ValueLocationAmenities
4.94 out of 5 average rating, 103 reviews
Serenity, Starlink and waking up with bird songs
Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.
FamilyLocationAccuracy
5.0 out of 5 average rating, 40 reviews
Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).
FamilyLocationHospitality
4.94 out of 5 average rating, 170 reviews
A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!
FamilyLocationOutdoor spaces
5.0 out of 5 average rating, 142 reviews
Mesquite Haven
Fantastic home located in a peaceful and beautiful community surrounded by desert nature. This Santa Fe style residence invites you to relax and escape a busy lifestyle while still having access to modern amenities. Enjoy life outdoors in a basically traffic free private community rich with local flora and fauna. The location is great for morning or evening walks or runs, Tubac Resort wedding guests, visits to the village, hiking trips, etc.
FamilyLocationLong stay
5.0 out of 5 average rating, 22 reviews
Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.
FamilyLocationHeating
4.98 out of 5 average rating, 290 reviews
Winemaker's Casita in the heart of Wine Country
The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.
FamilyLocationSleep quality
4.99 out of 5 average rating, 358 reviews
Poolside Escape Near Patagonia
Unwind at this scenic hilltop retreat just a mile south of Patagonia, AZ. Enjoy a private pool with stunning Red Mountain views, 3 spacious bedrooms, and a dedicated office space. Close to hiking, biking, and town. Relax in modern comfort, soak up breathtaking sunsets, and explore the best of Southern Arizona. Pet-friendly for making memories with the whole family!
ValueLocationWi-Fi
4.94 out of 5 average rating, 72 reviews
Large group getaway - 4 bed w/ updated appliances
Welcome to this new construction 4-bedroom, 2-bathroom home in Rio Rico! Perfect for families or groups. Enjoy an open-concept living space with a gourmet kitchen, granite countertops, and stainless steel appliances. Visit nearby attractions such as Tumacácori National Park, explore nearby Tubac & Nogales AZ, or enjoy family time by the fire pit!
LocationFamilyLaundry
4.98 out of 5 average rating, 43 reviewsPopular amenities for Santa Cruz County house rentals
House rentals with a pool

Valle Verde Ranch House.
LocationFamilyDecor
5.0 out of 5 average rating, 5 reviews
Hacienda de Nomada
LocationFamilyWalkability
5.0 out of 5 average rating, 10 reviews
Cozy 2 bedroom townhouse, Tubac
LocationFamilyComfort
4.95 out of 5 average rating, 22 reviews
Gallo Libre Ranch House in Arivaca, Arizona
ValueLocationHospitality
4.98 out of 5 average rating, 40 reviews
Stylish Townhome, 2BD, 2BA-Pool & Gym Access.
ValueLocationPool
4.95 out of 5 average rating, 44 reviews
Rio Rico Resort
FamilyOutdoor spacesHospitality
5.0 out of 5 average rating, 4 reviews
Beautifully Bewitching Mansion Indoor Pool
FamilyLocationSleep quality
5.0 out of 5 average rating, 3 reviews
Enjoy Tubac’s best view from your own upscale spa
LocationValueKitchen
4.78 out of 5 average rating, 41 reviewsWeekly house rentals

Peaceful Oasis in The High Desert
FamilyLocationView
5.0 out of 5 average rating, 4 reviews
Adobe Retreat | Walk to Tubac Golf Resort
LocationValueBarbecue
4.82 out of 5 average rating, 67 reviews
Camp Cathy
FamilyLocationComfort
5.0 out of 5 average rating, 16 reviews
Fully private casita in heart of town!
ValueLocationDecor
4.94 out of 5 average rating, 31 reviews
Tubac House
LocationFamilyCheck-in
4.86 out of 5 average rating, 14 reviews
Vino y Vacas - Cozy Home - Heart of Wine Tasting
LocationAir conditioningKitchen
4.95 out of 5 average rating, 19 reviews
Desert Oasis Retreat
LocationViewKitchen
4.89 out of 5 average rating, 9 reviews
Sonoita View Property
FamilyLocationKitchen
5.0 out of 5 average rating, 32 reviewsPrivate house rentals

Cozy stay in wine country at Penelope's Place
LocationFamilyTV
5.0 out of 5 average rating, 11 reviews
Downtown Sonoita Casita
ValueLocationAccess
4.89 out of 5 average rating, 36 reviews
Barrio Bungalow
LocationFamilyQuiet
5.0 out of 5 average rating, 15 reviews
Historic Gomez House
FamilyLocationComfort
5.0 out of 5 average rating, 9 reviews
Tres Bellotas Ranch Guest House
FamilyLocationCleanliness
4.96 out of 5 average rating, 24 reviews
Ranger Trail Camp
LocationFamilyShared spaces
5.0 out of 5 average rating, 4 reviews
YELLOW HOUSE NEAR THE BORDER
ValueLocationHospitality
4.75 out of 5 average rating, 28 reviews
Cosy House: Studio - great WiFi and RO water
ValueLocationWalkability
4.94 out of 5 average rating, 94 reviewsDestinations to explore
- University of Arizona
- University of Arizona
- Saguaro National Park
- Arizona-Sonora Desert Museum
- Tucson Convention Center
- Tumamoc Hill
- Patagonia Lake State Park
- Kartchner Caverns State Park
- Sabino Canyon Recreation Area
- Titan Missile Museum
- Tucson Botanical Gardens
- Reid Park Zoo
- Tucson Museum of Art
- Mission San Xavier del Bac
- Pima Air & Space Museum
- Rialto Theatre
- Tumacacori National Historical Park
- Sonoita Vineyards
- Children's Museum Tucson
- Trail Dust Town
- Mini Time Machine Museum of Miniatures
- Tubac Presidio State Historic Park
- Roy P Drachman - Agua Caliente Regional Park
- Mercado San Agustin





