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Holiday houses in San Diego, Santiago

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in San Diego, Santiago

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 19 reviews

Downtown Santiago Apt with Private Terrace and BBQ

Unwind above Santiago’s bustling core on your private terrace complete with BBQ and sweeping skyline views. Step inside a bright 1-bed flat with fast Wi-Fi, comfy pillows, TV, and a fully stocked kitchen. Location: Walk 5 min to Cerro Santa Lucia and its metro station, cafés, museums and iconic buildings. Sleep & relax: King bed, blackout curtains, extra pillows and blankets. Extras: Rooftop pool, 24-hr doorman, smart TV, bidet, hammock and lot of sunlight. Book your downtown stay today!

Top Guest favourite
A dining table is set with two place settings, featuring dark plates and wine glasses. A decorative centerpiece of dried plants adds a natural element. A modern black couch is visible in the background along with abstract artwork that introduces color and texture to the space.
Apartment in Santiago
4.98 out of 5 average rating, 47 reviews

Apartment in Santiago Centro

Cozy apartment in the heart of the city, its privileged location, close to restaurants, museums and cultural life, 5 min. from the subway, government palace and bulnes promenade. Here you'll find everything you need for a comfortable and quiet stay. Includes complimentary coffee, streaming service, bed linen and towels. We have special services (birthday, anniversary or simply surprise your companion) with prior notice and additional cost. If you have any questions, please contact me :)

Guest favourite
A spacious bedroom features a comfortable bed with plush pillows, accented by decorative wall art made of natural materials. A wooden ladder stands against the wall, and bedside tables with lamps are positioned on either side of the bed, enhancing the room's cozy atmosphere.
Apartment in Santiago
4.95 out of 5 average rating, 154 reviews

Modern apartment in the heart of the Santa Lucia neighborhood, 1 bedroom

Comfortable and cozy accommodation New and modern building steps away from Santa Lucia metro station so you can get around wherever you want. The perfect place to feel right at home. Where you can enjoy a comfortable king-size bed! A coffee maker for coffee lovers, a bottle of purified water, and some cold beers to help you relax. Everything designed for you to have a pleasant stay! I'm Francisca and I'm available 24/7! I look forward to having you stay with us

Top Guest favourite
Apartment in Santiago
4.92 out of 5 average rating, 12 reviews

Santiago Centro • Downtown • Great Connectivity & WiFi

Welcome to your home in the heart of the city. This modern apartment is located in the center, steps from restaurants, cafes, museums and public transport. Ideal for those who want to enjoy the city walking. The space has been designed with style and functionality: - Comfortable bed - Living room and bedrooms with TV - Kitchen equipped to cook like at home - Fast WiFi - Modern bathroom and toiletries Here you will find everything for a perfect and quiet stay.

Guest favourite
A cozy bedroom features a spacious bed adorned with decorative pillows and a patterned comforter. Bedside tables hold small lamps, while a piece of wall art adds visual interest. Natural light filters through sheer curtains, creating a bright and inviting space.
Apartment in Santiago
4.89 out of 5 average rating, 151 reviews

Apartment in Santiago Centro

Your family will be close to everything when you stay in this centrally located accommodation. Close to historic downtown, venues for big events and universities. Reception 24 hours a day. New, full-equipped apartment with a 2-plax bed, and an armchair bed. WIFI, full equipped kitchen, large 55 TV, hairdryer, iron and towels. Steps away from the Parque Almagro metro. Minutes from Moneda, Teatro Caupolicán, Movistar Arena. Secure parking within the building.

Guest favourite
Apartment in Santiago
4.92 out of 5 average rating, 150 reviews

Central Apartment with A/C a few steps from the Metro

Entire apartment in Santiago Centro, equipped with air conditioning (hot/cold) from September 2025. 24/7 security. 3 min walk to Parque Almagro metro and Teatro Caupolicán. It is only 7 blocks from the Alameda and Centro Cultural La Moneda. It is the ideal place for people who want to go to events in the Caupolicán or to do tourism in the city. The apartment has 2 rooms, a living-kitchen and a bedroom. Additionally it has a small terrace ideal for smoking.

Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 14 reviews

Modern and elegant, close to Movistar Arena.

Modern apartment in Santiago Centro boutique building, ideal for business trips or tourism. Fully equipped: air conditioning, kitchenette, TV, 2-seater bed and extra sofa bed. Located just steps from Parque O’Higgins, Movistar Arena, Palacio Cousiño and other attractions. Excellent connectivity with metro stations nearby. The building has quinchos, gym, gourmet lounge, and 24/7 security. Comfort, style, and location in one place.

Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 17 reviews

Beautiful and Clean | Panoramic View | Large Terrace

Welcome to the heart of Santiago! Enjoy 24/7 security🔐, total comfort, 🛋️ and prime location📍 - steps from Metro Santa Lucia🚇, Cerro Santa Lucía🌄, cafes☕, supermarkets, 🛒 and nightlife in Lastarria🎭. Walk to La Moneda Palace and in 15 minutes by metro to the bohemian Bellavista . Wi-Fi 600 Mb, Smart TV 42″, balcony🌿, pool 🏊‍♂️ and gym🏋️. Will you miss the mountains in winter? Talk to me

Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 9 reviews

Loft with balcony and view near La Moneda

Spacious and bright apartment in the heart of Santiago🌆. Ideal for travellers looking for comfort, independence and a great view of the city. With a warm and functional design, it offers fast Wi-Fi, Smart TV, equipped kitchen and cozy spaces. Located near the metro, cafes, museums and the main tourist attractions, it is the perfect place to enjoy Santiago on foot and rest in comfort.

Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 8 reviews

HOM I Apartment 2PAX Metro Parque Almagro

🏡 ¡Bienvenidos a un acogedor apartamento en Santiago Centro ✨ 📍 Ubicación privilegiada en el corazón cultural y artístico de Santiago 🏙️ 🚇 A solo 2 minutos caminando del metro Parque Almagro y 12 minutos del metro Universidad de Chile 🏛️ A pocos minutos del Palacio de La Moneda y de barrios vibrantes y turísticos, Ubicado justo frente a la impresionante Iglesia Sacramentinos

Top Guest favourite
Apartment in Santiago
5 out of 5 average rating, 13 reviews

New apartment in Metro Santa Lucia 608

New and modern fully equipped apartment, located 10min from Metro Santa Lucía. Ideal for tourists or travelers for work. It has a private terrace, equipped kitchen, Smart TV, WiFi, modern bathroom and everything you need for a comfortable stay. Minutes from Barrio Lastarria, Cerro Santa Lucia, museums, cafes and restaurants. Perfect for enjoying Santiago from downtown!

Top Guest favourite
An open-plan living area features modern furnishings, with a light wooden dining table set for four. A sleek kitchen with minimalistic cabinetry is visible in the background. Large glass doors provide access to an outdoor terrace, enhancing the bright and airy feel of the space.
Apartment in Santiago
5 out of 5 average rating, 26 reviews

Beautiful 1D1B 2PAX Wifi Air A. Metro Sta. Lucia P9

Warm apartment, carefully decorated and fully equipped to provide you with a comfortable and relaxing experience. Just a few steps from Santa Lucía Metro Station ( Line 1 ) and Cerro Cerro Santa Lucia, supermarkets, banks, medical clinic, dental and aesthetic clinic, pharmacies and coffee shops. Ideal for a short or long term stay, adapting to all your needs.

Popular amenities for San Diego, Santiago holiday rentals