
Holiday houses in San Antonio
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Top-rated holiday rentals in San Antonio
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Colonial House | Historic Center | Cristo Rey View
Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Cozy+Unique Loft/Touch of Nature/High Speed WiFi
*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

El Peñón Gem | Prime Location with Private Jacuzzi
★ Prime Location with Private Jacuzzi ★ Welcome to your stylish escape in Cali's most vibrant neighborhood. This modern 2-bedroom apartment offers everything you need for a comfortable and memorable stay, including a private jacuzzi, king & queen beds, A/C in every bedroom and dedicated parking, all just steps from top restaurants, cafes, and landmarks. Whether you're here to dance, explore or work remotely, this apartment brings you closer to everything that makes Cali unforgettable.

Panoramic Suite Overlooking Colonial Cali
Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Beautiful Colonial Apartment San Antonio Centre
The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Villa del Peñon 301 - 2-Bed With Nice Balcony
🌴 EXSTR APARTMENT • Villa del Peñon 301 This two bedroom, two bathroom unit with a balcony, is the perfect match for families, groups of friends, or digital nomads. All tabs have hot water, the bedroom has A/C, smart TV, and a queen bed. All the amenities are in place and have been designed with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

OM Studio Rooftop at San Antonio - Cali.
Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

402Studio with balcony in top area + AC and Netflix
Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Granada Penthouse | 4 People | Rooftop Pool & Gym
Luxury penthouse studio in Cali’s vibrant Granada district with stunning city views. Ideal for solo travelers, couples or small families. Sleeps up to 4: queen bed and sofa bed that converts into a comfortable queen bed. Note: **Total reservation cost varies by total number of guests** Enjoy full kitchen, in-unit laundry, terrace, plus access to pool, gym, spa, coworking, and meeting rooms. RNT: 251456

Chic Apartment with Private Terrace in San Antonio
Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI
** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Private Patio & Rooftop with Design in San Antonio
Ubicado en el emblemático barrio San Antonio, este apartamento te permite moverte caminando hacia el Bulevar, restaurantes, cafés, Club nocturnos , academias de salsa y supermercados, mientras descansas en un entorno residencial y tranquilo al regresar. Es una opción muy cómoda para quienes trabajan remoto, visitan familia o planean quedarse varios días en Cali.
Popular amenities for San Antonio holiday rentals
Other great holiday rentals in San Antonio

H502 Stunning 1BR , Pool, Parking, 24/7 Guards

203 • Furnished room • Unbeatable location.

Exceptional Study San Antonio

Spectacular Apartment, Prime Location & Garden

Crs 403 - Charming 2 Br Apt in Centenario w/ Queen

Private Flat with patio at San Antonio - Cali

Villa del Peñon 302 - 1-Bed With Quiet Comfort

Luxurious Studio in San Antonio
Destinations to explore
- Chipichape Centro Comercial
- Estadio Olímpico Pascual Guerrero
- Basilica of the Lord of Miracles
- Zoologico de Cali
- Parque del Perro
- Acuaparque de la Cana
- La Topa Tolondra
- Pontificia Universidad Javeriana Cali
- Ingenio Park
- Coliseum of the People
- The River Cat
- Parque Artesanal Loma De La Cruz
- Parque de los Gatos
- Palmetto Plaza
- Cosmocentro
- Jardín Plaza
- Estatua de Sebastian de Benalcazaz
- Unicentro Cali Shopping Mall
- Iglesia De San Antonio
- Parque Versalles
- Iglesia La Ermita
- Hacienda El Paraiso
- Galería Alameda
- Plazoleta Jairo Varela




