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Holiday houses in San Antonio

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Top-rated holiday rentals in San Antonio

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Top Guest favourite
An open living area features high ceilings and a striking wooden staircase leading to the upper level. Below, a well-equipped kitchen is arranged with modern bar stools, while a cozy seating area is accentuated by a patterned rug and a decorative plant nearby.
Home in San Cayetano
5 out of 5 average rating, 48 reviews

Colonial House | Historic Center | Cristo Rey View

Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. In December, Cali wakes up magical: sweet breeze, bright colors and nights that beat to the rhythm of salsa. If you want to live an authentic Caleña experience — culture, flavor, rhythm and human warmth — this is the place. We are in the heart of the Historic Center, within walking distance of restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Apartment in San Antonio
4.89 out of 5 average rating, 64 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favourite
Apartment in El Peñol
5 out of 5 average rating, 13 reviews

El Peñón Gem | Prime Location with Private Jacuzzi

★ Prime Location with Private Jacuzzi ★ Welcome to your stylish escape in Cali's most vibrant neighborhood. This modern 2-bedroom apartment offers everything you need for a comfortable and memorable stay, including a private jacuzzi, king & queen beds, A/C in every bedroom and dedicated parking, all just steps from top restaurants, cafes, and landmarks. Whether you're here to dance, explore or work remotely, this apartment brings you closer to everything that makes Cali unforgettable.

Guest favourite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Apartment in San Antonio
4.96 out of 5 average rating, 27 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Guest favourite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Apartment in San Antonio
4.87 out of 5 average rating, 79 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Top Guest favourite
A well-lit bedroom features a spacious bed draped in crisp white linens and accented with decorative pillows. A green accent wall provides a fresh touch, while large glass doors lead to a balcony with views of surrounding trees, adding to the room's inviting atmosphere.
Apartment in El Peñol
4.97 out of 5 average rating, 182 reviews

Villa del Peñon 301 - 2-Bed With Nice Balcony

🌴 EXSTR APARTMENT • Villa del Peñon 301 This two bedroom, two bathroom unit with a balcony, is the perfect match for families, groups of friends, or digital nomads. All tabs have hot water, the bedroom has A/C, smart TV, and a queen bed. All the amenities are in place and have been designed with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

Top Guest favourite
Apartment in San Antonio
4.96 out of 5 average rating, 165 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favourite
Apartment in San Antonio
4.89 out of 5 average rating, 88 reviews

402Studio with balcony in top area + AC and Netflix

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Guest favourite
A serene bedroom features a spacious bed with soft linens and decorative pillows. Two bedside lamps provide gentle lighting, while a wooden nightstand holds a small plant. Natural light enters from a nearby balcony door, enhancing the modern decor.
Apartment in Granada
4.89 out of 5 average rating, 37 reviews

Granada Penthouse | 4 People | Rooftop Pool & Gym

Luxury penthouse studio in Cali’s vibrant Granada district with stunning city views. Ideal for solo travelers, couples or small families. Sleeps up to 4: queen bed and sofa bed that converts into a comfortable queen bed. Note: **Total reservation cost varies by total number of guests** Enjoy full kitchen, in-unit laundry, terrace, plus access to pool, gym, spa, coworking, and meeting rooms. RNT: 251456

Top Guest favourite
Apartment in San Cayetano
4.98 out of 5 average rating, 46 reviews

Chic Apartment with Private Terrace in San Antonio

Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

Guest favourite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Apartment in Centenario
4.93 out of 5 average rating, 118 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Guest favourite
A dining setup is presented on a stylish terrace table, featuring a plate of pasta and cured meats alongside a bottle of red wine and glasses. A decorative vase with an orchid adds a touch of elegance, with a panoramic view of the city landscape in the background.
Apartment in San Antonio
4.96 out of 5 average rating, 68 reviews

Private Patio & Rooftop with Design in San Antonio

Ubicado en el emblemático barrio San Antonio, este apartamento te permite moverte caminando hacia el Bulevar, restaurantes, cafés, Club nocturnos , academias de salsa y supermercados, mientras descansas en un entorno residencial y tranquilo al regresar. Es una opción muy cómoda para quienes trabajan remoto, visitan familia o planean quedarse varios días en Cali.

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio