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Holiday houses in San Antonio

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Apartment in El Peñol
4.96 out of 5 average rating, 152 reviews

El Peñon Penthouse - Private Terrace and Cool View

🌴 EXSTR APARTMENT • Brisas del Peñón 401 Stylish 2 bedroom, 2 bathroom penthouse with beautiful views of Cali’s iconic Three Crosses. Enjoy fast 300 Mb Wi-Fi, two workstations (one with electric desk + monitor), SmartTVs, A/C in bedrooms, and noise-reducing windows in the master bedroom. The private terrace features outdoor dining, a BBQ, and a small kitchen — perfect for soaking in Cali’s warm evenings. Located on quiet tree-lined street, steps from Krost bakery and all the best of El Peñon.

Guest favourite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Apartment in San Antonio
4.88 out of 5 average rating, 82 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Top Guest favourite
Apartment in San Antonio
4.97 out of 5 average rating, 33 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Top Guest favourite
Apartment in El Peñol
5.0 out of 5 average rating, 26 reviews

El Peñón Gem | Prime Location with Private Jacuzzi

★ Prime Location with Private Jacuzzi ★ Welcome to your stylish escape in Cali's most vibrant neighborhood. This modern 2-bedroom apartment offers everything you need for a comfortable and memorable stay, including a private jacuzzi, king & queen beds, A/C in every bedroom and dedicated parking, all just steps from top restaurants, cafes, and landmarks. Whether you're here to dance, explore or work remotely, this apartment brings you closer to everything that makes Cali unforgettable.

Guest favourite
Home in San Antonio
5.0 out of 5 average rating, 32 reviews

Casa colonial en San Antonio terraza espectacular

Disfruta de una estancia única en nuestra casa ubicada en el emblemático barrio colonia San Antonio, Cali. Nuestro alojamiento combina comodidad y frescura, y está equipado con todo lo que puedas necesitar. Rodeado de una vibrante variedad de tiendas, restaurantes, miradores, mercado de artesanías. Además, la cercanía a lugares turísticos te permitirá explorar fácilmente nuestra ciudad. Relájate en nuestra casa colonial y disfruta de la mejor vista panorámica desde nuestra terraza privada.

Guest favourite
Apartment in San Antonio
4.9 out of 5 average rating, 117 reviews

402Studio con balcón en zona top + AC y Netflix

Ubicado en El Peñón, uno de los barrios más seguros y tranquilos de Cali. A pasos del Hotel Dann Carlton 5⭐️, rodeado de restaurantes, bares, discotecas, casino, museo y parque. Contamos con aire acondicionado, WiFi rápido, TV con apps de streaming y zona de lavandería 24/7 gratis. Se puede escuchar el paso de vehículos. Ideal para disfrutar la ciudad con comodidad y excelente ubicación. Además, ofrecemos un ambiente limpio, acogedor y con atención rápida ante cualquier necesidad.

Guest favourite
Apartment in San Antonio
4.92 out of 5 average rating, 62 reviews

Casa Balita - Design and History - Loft Duplex

Enjoy this cozy stay at Casa Balita, ideally located in the traditional San Antonio neighborhood, a cultural and architectural heritage, on Cobblestone Street. The area offers a wide range of dining and cultural experiences. Just a few meters away, explore the El Peñón neighborhood, and only two blocks away, the iconic Loma de San Antonio with its beautiful church. Additionally, the accommodation features a shared terrace with a city view. An ideal place for your stay in Cali!

Top Guest favourite
Apartment in San Antonio
4.96 out of 5 average rating, 192 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Top Guest favourite
Apartment in San Antonio
4.98 out of 5 average rating, 46 reviews

Apto Cerca a todo, Peñon, zona Turística Tina, A/C

✨ Moderno y acogedor apartamento en el exclusivo barrio el peñon Disfruta caminando el Boulevard del Río, Gato de Tejada, San Antonio, y relajate visitando los mejores restaurantes de Cali, bares y discotecas en la zona. ¡Te esperamos! Nota: Como varios edificios clásicos del Peñón, no tiene ascensor; el acceso es por escaleras. Es ideal para parejas y personas solas que quieren alojarse a pasos de los sitios más emblematicos y divertidos de cali.

Top Guest favourite
A dining setup is presented on a stylish terrace table, featuring a plate of pasta and cured meats alongside a bottle of red wine and glasses. A decorative vase with an orchid adds a touch of elegance, with a panoramic view of the city landscape in the background.
Apartment in San Antonio
4.95 out of 5 average rating, 80 reviews

San Antonio | Private patio, Wi-Fi, remote work.

Located in the iconic San Antonio neighborhood in Cali. You can easily walk to the Bulevar del Río, Calle del Sabor, restaurants, cafés, museums, bars, salsa academies, and supermarkets. In approximately 10 minutes, you can also reach places such as the Cali Zoo, Cristo Rey, the Botanical Garden, and El Gato de Tejada. It is a comfortable and quiet option for guests working remotely, visiting family, or planning to stay several days in Cali.

Guest favourite
Apartment in Juanambu
4.93 out of 5 average rating, 138 reviews

IN105 Oasis de lujo |Jacuzzi privado | WIFI 350mb

** UNIDAD EXCLUSIVA SIN CARGOS POR SERVICIO DE AIRBNB ** Bienvenido a nuestro lujoso loft en Cali, inspirado en la naturelza. Con 44m², jacuzzi privado al aire libre y capacidad para 2 personas, es un oasis contemporáneo, agua caliente. Sala, comedor y cocina equipada ofrecen comodidad y estilo. Habitación privada y baño completo garantizan un descanso reparador. Ubicación inmejorable cerca de puntos turísticos.

Guest favourite
A modern dining area features a wooden table surrounded by two black woven chairs. A simple vase holds decorative dried foliage, positioned on the table. Stylish cabinetry with warm lighting enhances the contemporary ambiance, complemented by decorative items displayed on the shelves.
Apartment in San Antonio
4.9 out of 5 average rating, 125 reviews

Jungle Loft · Iconic Entrance · San Antonio

You'll know this place the moment you see the door. 🌿 A lush ivy-covered entrance, a dramatic red staircase climbing through a living plant wall, dark moody interiors and boho-chic details throughout. This two-level duplex in San Antonio is genuinely unlike anything else in Cali. More than 120 guests have stayed and loved it. Steps from the best salsa, restaurants and nightlife in the city.

Popular amenities for San Antonio holiday rentals