
Family-friendly holiday rentals in Saint Charles
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Saint Charles

Total holiday rentals
Explore 150 holiday rentals in Saint Charles

Nightly prices starting at
Saint Charles holiday rentals start at $113 AUD per night before taxes and fees

Verified guest reviews
Over 12,550 verified reviews to help you choose

Pet-friendly accommodation
Find 80 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
150 of Saint Charles holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Saint Charles rentals

4.8 Average rating
Saint Charles stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Saint Charles
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

The Ella Rose Guest Suite steps from Main Street
Welcome to The Ella Rose Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. The Ella Rose is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Come sit and listen to the music of our outdoor bubbler rock.
Indoor spacesKitchenRiver

BEAUTIFUL Historic 3 Bedroom Upscale Guesthouse!!
Spacious luxury three bedroom home in historic St. Charles. Minutes away from Main Street, Frenchtown, Streets of St. Charles, shopping, and more. The bright, fully equipped chef's kitchen features a gas range, spacious counters, and upscale appliances for all your dining and entertainment needs. Bedrooms include luxury DreamCloud Mattresses and upscale bedding. Full size washer/dryer, walk in closet, and Roku. Dream bathrooms with soaker tub. Backyard features outdoor relaxation and playhouse.
KitchenIndoor spacesHiking

301 Guesthouse- Historic Main street-Katy Trail
Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!
KitchenIndoor spacesComfort

Cottage on Historic Main St- Low Cleaning Fee
MESSAGE FOR SHORT STAY DISCOUNT Walk to everything on Historic Main Street St. Charles! Stay in a stylish 2BR steps from top dining, shops, nightlife & Ameristar Casino. 12 mins to STL Airport. Fast Wi-Fi, Smart TV’s, full kitchen, free parking & easy self check-in. Perfect for couples, weekend getaways & business stays. Unbeatable location, step outside directly onto Main Street in this vibrant, walkable district. Check out our 5★ reviews! Come check our top rated place in St. Charles, MO.
FamilyKitchenLocation

Tompkins Street Retreat
Relax in this two-bedroom, two-bath house with a backyard patio and firepit with a privacy fence. Walk to unique shopping and entertainment on Historic St. Charles Main Street. Local wineries and St. Louis attractions are a short drive away. Enjoy a comfortable living room with a large TV and a fully equipped kitchen for special meals. Unwind after an active day with a meal, drinks under the pergola, and a great night's sleep in our king-size bed. We also offer FREE off-street/garage parking.
FamilyKitchenValue

Patio House, secluded in heartbeat of Main Street
The Patio is nestled in the heart of historic St. Charles a few steps from Main Street, Katy Trail, Missouri River, Antique and Boutique Shopping, Restaurants Bars and More, Several Wedding venues are within walking distance of the property as well. In addition to your well appointed unit, this property has as much outside as it does in. Take your coffee, wine, water and enjoy our patio, complete with fire table, dining table edged with lush plantings for privacy. PLEASE NOTE NO SMOKING
FamilyKitchenCheckout

*NEW HotTub* The Jewel on 5th-2br2b-near Main
A true gem only a 15 min drive from the STL Airport. Enjoy a well equipped, century home a short 12 min walk to Historic Main and a HOTTUB. The large stocked kitchen is great for entertaining. Master bedroom w/luxurious, king sized, 4 poster bed and ensuite bathroom awaits you. In the private, queen suite you’ll find its own bathroom and another door leading onto the deck. The chair off the kitchen folds out to a standard twin and bedding is provided for the sofa as well. Can sleep 6.
Indoor spacesKitchenWi-Fi

Family/4bd/2bth/Huge Yard/Playset/Ping-Pong/Arcade
Our freshly updated and furnished house is ready for the family with kids, the adult getaway, and wedding parties from Stone House event venue across the street! Boasting tons of privacy, a huge yard with a playset and games, a fully stocked kitchen with everything you could want for a Thanksgiving dinner, and a large basement with arcade boxes, ping pong, weights, and seating areas. A very safe and secluded location that is close to amazing parks, restaurants, wineries, and shopping.
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Bright & Cozy Shotgun DPX 1 Block from Historic DT
Admire this unique historic home's design with brand new amenities and antique details that give a fresh and charming feel. Built in the late 1800's, this half of the duplex has a typical shotgun layout with ten-foot ceilings giving a spacious feel. The front door leads directly to the living room, then into the bedroom, both of which have the original hard wood floors. The back of the house has the kitchen, with exposed brick, a dining area, and a bathroom with a washer and dryer.
FamilyKitchenAccess

Camp Mill Pond: Historic Cabin Near Main Street
*St. Louis Magazine A-List Winner!* ***PRESS: DESIGN STL, STL MAG, AND FOX2NEWS*** Camp Mill Pond is a throwback to the slow and easy rhythm of hot summer days. This circa 1835 cabin offers easy access to our historic area, including Main Street, Katy Trail for biking, and Frenchtown, without sacrificing modern comforts! This 180-year-old historic cabin sits on a beautiful lot, shared with our 1865 three-story home and a two-story carriage house. Ask about renting bikes! 🚲
KitchenIndoor spacesGetting around

The Frenchtown Inn | 2BR Charmer
Welcome to the Frenchtown Inn on the corner of Third and French! Experience the best of St. Charles in this charming 2-bedroom, 2-bathroom house situated in the heart of Frenchtown. This delightful space offers a perfect blend of comfort, convenience, and a touch of history, ideal for an unforgettable stay. We are dog friendly, complete with a fenced in yard. The Frenchtown Inn awaits you. Come experience a memorable, relaxing getaway with family or friends in our inviting home!
Indoor spacesFamilyHospitality

Cozy Studio in Beautiful New Town St. Charles
Stay at this cozy studio centrally located in the amazing community of New Town St. Charles. New Town is a large scale new urbanist community built on the edge of suburbia. You never have to leave New Town with its walkability to restaurants, bars, a market, coffee shops, ice cream, food kiosk, canals, lakes, parks and tree lined streets. If you do leave its only a few miles from historic St. Charles Main street, The Streets of St. Charles, and 25 miles to Downtown St. Louis.
Indoor spacesFamilyParking
Popular amenities for Saint Charles family-friendly rentals
Family-friendly home rentals with a hot tub

Blair's Jungle House w/ Hot Tub - Game Room
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Romantic tiny home w/ hot tub
Indoor spacesFamilyHot tub

“HOT TUB” Oasis in the heart of the city!
FamilyIndoor spacesComfort

Spacious 6BR Retreat | Near I-64 & Weddings
Indoor spacesKitchenOutdoor spaces

Roomy Oasis with hot tub on the Hill!
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Lodge at Pine Lake - Hot tub, lake, pets welcome
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Cul De Sac - next to the best shopping in STL
Indoor spacesFamilyAir conditioning

The Soulard Atelier- Hot Tub!
Indoor spacesFamilyDecor
Family- and pet-friendly home rentals

The Benton House - With fenced yard!
Indoor spacesFamilyAccess

Cozy Mid-Century Modern Townhome
Indoor spacesFamilyCondition

Little House By Main St -5 4K TV's- 1-75 Inch -1GB
Indoor spacesFamilyPets

Route 66 Railroad Shanty, a cozy artsy small space
Indoor spacesKitchenOutdoor spaces

Pacific Palace, super unique!
FamilyIndoor spacesParking

Wooded Oasis Free Bottle of wine+brkfst+golf
Indoor spacesKitchenLong stay

The Ladybug Inn
KitchenFamilyAir conditioning

Route 66 Cozy Cottage
FamilyIndoor spacesWalkability
Family-friendly home rentals with a pool

Spacious Home - Heated Pool Open Extended Season
KitchenFamilySleep quality

Private indoor pool & sauna
FamilyKitchenQuiet

Sunset Mountain Privacy
Indoor spacesFamilyLong stay

Large U. City Apt 4 BR, 2 Bath, Pool, near Wash U.
Indoor spacesKitchenCheck-in

Tower Grove Oasis #1 + King Bed + Queen Bed+ Patio
Indoor spacesKitchenHospitality

Cabin+LAKE! Fish-swim-kayak*Near Purina & SixFlags
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T Sweet St. Louis Airport 2 bedrooms Apartment
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Secluded Property w Pool and Hot Tub
FamilyIndoor spacesComfort
Destinations to explore
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- Busch Stadium
- Central West End
- Six Flags St. Louis
- Saint Louis Zoo
- The Dome at America's Center
- Enterprise Center
- St. Louis Aquarium at Union Station
- Gateway Arch
- City Museum
- Missouri Botanical Garden
- Washington University in St Louis
- Forest Park
- Hidden Valley Ski Resort
- Meramec Caverns
- Saint Louis University
- The Pageant
- Castlewood State Park
- Gateway Arch National Park
- Soulard Farmers Market
- Saint Louis Science Center
- Westport Plaza
- Saint Louis Art Museum
- Missouri History Museum
- Fabulous Fox





