
Holiday houses in Osborn Medical Center, Phoenix
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Top-rated holiday rentals in Osborn Medical Center, Phoenix
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Best Little Guesthouse in Melrose !
Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Paradise Found, Conferences, Concerts, GCU, Pool
The historic Willo district of Central Phoenix is the perfect location to relax. Close to many attractions and major freeways, this completely renovated mid-century home offers the ultimate in both luxury and high-end fixtures. Inside, you can pamper yourself in the deep tub (with endless hot water) or multi-faucet shower, snuggle in the luxurious beds, or just laze in front of the 65" 4K TV. Outside, you can relax beside the pool (ask about heating), or just gather under the shaded patio.

Spacious Midtown guesthouse with full privacy
Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

PHX's Modern Midtown Carriage House, Free Parking
Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious queen bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

Private, Sparkling Clean Historic DTPHX Guesthouse
This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Private, desert-chic casita in vibrant Midtown PHX
Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Spacious Studio in Uptown Historic Neighborhood
Discover Uptown Phoenix and its vibrant charm! Nestled in the historic district, our property offers a serene escape in the heart of the Valley. This spacious, private studio features a resort-style outdoor retreat, a shared courtyard, a gourmet grill, two outdoor dining areas, and a cozy fire pit to unwind. Inside, relax in a comfortable living room, enjoy meals or card games at the dining table, and retreat to a glamorous bedroom for the perfect end to your day.

The Beverly Bungalow | Stylish Stay Near Downtown
Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2. Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Guesthouse in city's most walkable neighborhood
Central location, easy access to I-10, I-17, 202, 51, and 9 minutes from Phoenix Sky Harbor Airport. Amenities abound in this updated private studio guesthouse in the upscale Encanto-Palmcroft Historic District of downtown Phoenix. Homes here have stunning architectural diversity. Recently ranked the wealthiest neighborhood in Phoenix, Phoenix Magazine named Encanto-Palmcroft 2009's "Best Places to Live" and the "Best Neighborhood to Walk Through" in 2015.

Adorable Willo Cottage in Historic Central Phoenix
Peaceful one bedroom cottage in unbeatable location within Central Phoenix. Walking/ biking distance from light rail, restaurants, Heard Museum and Phoenix Art Museum. Enclosed backyard with a shared washer/dryer on property. The cottage has a queen bed, mini kitchen and private patio. Property is cleaned and sanitized according to the Airbnb cleaning procedures. 15 minutes from Sky Harbor Airport. 5 minutes from Encanto Park (Golf Course)

Historic Casa in heart of Phoenix
This newly restored 1930's home is loaded with charm and amenities. Situated on a quiet cul-de-sac in the upscale Willo neighborhood, our casa is just a walk or short light rail ride from the heart of downtown Phoenix. From this unique location you can enjoy it all in true Phoenician style - food, drinks, arts, culture, music and sports! Plus easy access to Scottsdale, Tempe, hiking, golf, shopping and airport in <10 mile radius.

Family Friendly Home by Downtown with 3 Beds
Enter this beautifully remodeled 1946 home in the heart of Phoenix tucked away in the family-friendly Encanto Village community. Bright, spacious, airy and decorated to every detail for a proper vacation or for the perfect photo-op. Enjoy yourself with some fresh air as you are enjoying a drink in the front patio. Have a nice picnic or play in the grass in the backyard. Anywhere you want to go is within a short range.
Popular amenities for Osborn Medical Center, Phoenix holiday rentals
Other great holiday rentals in Osborn Medical Center, Phoenix

Midtown Apart ! Great Location !

Casita Calma Guesthouse | Mins to DT & Airport

Bungalow near Downtown Phoenix!

Coronado Cactus- Modern Historic DTPHX Bungalow

Historic Home Near Downtown | Full Kitchen & Patio

Mid-Century Modern Gem Midtown

Modern Phoenix Tiny Home | Studio | Near Hospitals

High-End Cowboy Casita w/ Private Patio & BBQ
Destinations to explore
- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- Sloan Park
- The Westin Kierland Golf Club
- Tempe Beach Park
- Peoria Sports Complex
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Desert Diamond Arena
- State Farm Stadium
- Arizona State University
- Grand Canyon University
- Camelback Ranch
- Salt River Tubing
- Surprise Stadium
- Goodyear Ballpark
- Scottsdale Stadium
- Papago Park
- We-Ko-Pa Golf Club
- Hurricane Harbor Phoenix
- Trilogy Golf Club at Power Ranch




