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House holiday rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total holiday rentals

    Explore 100 holiday rentals in Mytilini

  • Nightly prices starting at

    Mytilini holiday rentals start at $28 AUD per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    100 of Mytilini holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: These houses are highly rated for location, cleanliness and more.

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Guest favourite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home in Plomari
4.89 out of 5 average rating, 102 reviews

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

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Top Guest favourite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home in Mytilini
4.98 out of 5 average rating, 92 reviews

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

ValueFamilyAccuracy

Guest favourite
A serene cottage sits by the water's edge, framed by lush greenery and a distant hill. The home showcases a traditional design with a tiled roof and multiple windows, inviting bright natural light. The tranquil surroundings highlight the peaceful waterfront setting.
Home in Lesbos
5.0 out of 5 average rating, 28 reviews

Ambelos, Lesvos Beach House

Welcome to Ampelos Cottage, an 85 sqm beachfront retreat where the sea is right at your doorstep. Blending modern comfort with authentic Greek charm, it’s the perfect escape for families and couples seeking relaxation and unforgettable moments. Wake up to the sound of the waves, enjoy coffee by the sea and watch the sunset with a glass of wine. Explore Molyvos, discover the tavernas of Anaxos, or simply unwind surrounded by breathtaking sea and mountain views.

LocationFamilyNearby

Guest favourite
A modern villa is set against a night sky, with soft illumination highlighting its sleek design. The stone exterior is contrasted by bright lighting, creating a welcoming entrance. Lush greenery frames the scene, providing a touch of nature to the contemporary architecture.
Home in Lesbos Prefecture
5.0 out of 5 average rating, 14 reviews

Pieres Blanches Recidences

Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.

FamilyLocationComfort

Guest favourite
A spacious dining area features a long wooden table surrounded by modern black chairs. Large windows on either side allow natural light to fill the room, revealing views of the surrounding landscape. A stone fireplace adds a touch of warmth.
Home in Plomari
4.97 out of 5 average rating, 36 reviews

Iris Home

Our two-level recently renovated maisonette Iris Home is located in the city center. It has a fully equipped kitchen and dining area to enjoy your food with your family and friends overlooking the sea. The two bedrooms and the bathroom are on the lower level and continue the view of the endless blue of the Aegean Sea. Within a 2-minute walk, you can find the city's marina, restaurants, cafes and other shops.

LocationFamilyView

Guest favourite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home in Taxiarches
4.82 out of 5 average rating, 114 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

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Guest favourite
A double bed is positioned in a softly lit room, adorned with floral patterned bedding. A piece of wall art depicting a sunset is displayed above the bed, while decorative flowers frame the image. A warm ambiance is created by the light entering through a nearby window.
Home in Mytilini
4.83 out of 5 average rating, 41 reviews

Gina 's Cozy nest in Mytilene

Welcome to our apartment in the heart of Mytilene! Just steps away from restaurants and bars, we offer a comfortable double bed, personal care essentials, a fully equipped kitchen, a washing machine, and an iron. Enjoy free high-speed WiFi, a smart TV with Netflix, and air conditioning. We invite you to experience a unique stay filled with comfort, authentic hospitality, and unforgettable moments.

LocationAir conditioningNearby

Top Guest favourite
Home in Mytilini
5.0 out of 5 average rating, 21 reviews

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

ValueLocationCleanliness

Top Guest favourite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home in Nyfida
4.93 out of 5 average rating, 29 reviews

Pelagia's House

Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

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Guest favourite
Home in Mytilini
5.0 out of 5 average rating, 16 reviews

D. Bernardaki Garden House

Welcome to Bernardaki Garden House! Nestled in a traditional neighbourhood, our professionally designed apartment offers the perfect blend of modern comfort and timeless charm in the heart of Mytilene. Why does our proposal stand out among the options in the whole Mytilene? There's a reason, and we're eager to share it with you!

FamilyLocationQuiet

Guest favourite
A charming two-story house is presented, featuring a welcoming entrance framed by vibrant orange trees. Stone pathways lead to the door, where wooden shutters and a simple balcony adorn the exterior. Sunlight illuminates the façade against a clear blue sky.
Home in Pamfila
4.92 out of 5 average rating, 12 reviews

Traditional House

Stay with the whole family in this lovely accommodation with lots of space for moments of joy. The property is located near beautiful beaches As in the neighboring village of Panagiouda, you will find many markets, cafes, a gas station and leisure shops - taverns The city of Mytilene is 10-12 minutes away.

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Top Guest favourite
Home in Plomari
5.0 out of 5 average rating, 30 reviews

Villa olya plomari

A unique private villa in Plomari, with a breathtaking sea view, a quiet place, next to a pine forest with a luxurious private infinity pool and in the courtyard two sun beds and a dining area under an olive tree in front of the beautiful view of the sea and the village of Plomari. A perfect vacation.

LocationNearbyCleanliness

Popular amenities for Mytilini house rentals

When is the best time to visit Mytilini?

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Avg. price$99 AUD$96 AUD$98 AUD$116 AUD$132 AUD$136 AUD$126 AUD$147 AUD$118 AUD$106 AUD$105 AUD$102 AUD
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