Vacation rentals in Mark Twain Lake

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Top-rated holiday rentals in Mark Twain Lake

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Home in Palmyra
Cozy country 2-bedroom home with a view.
Make some memories at this unique and family-friendly place. Enjoy the view of horses grazing while sipping your morning coffee on the front porch. Take a drive to historic Hannibal, MO (11 miles) and Quincy, IL (18 miles). Book a guided farm petting zoo tour with the owners and/or a riding lesson on one of their many rodeo horses. This house sleeps 6 with a king bed, queen bed, and couch fold-out queen bed. The hostess is right next door to assist with any of your needs during your stay!
6 – 13 June
4.92 out of 5 average rating, 119 reviews
Guest favourite
Tiny home in Huntsville
O’s Barn Cabin - Small Town Livin'!
O’s Barn Cabin offers a simple and unique way of relaxing in rustic fashion! Our pet friendly tiny home is 532 sq. ft of open space and country character. The location is out of the city, yet just a couple miles from all of the stores you need. The little cabin is nestled down our shared private and peaceful driveway, with views of cattle grazing in the pasture right off the front porch at the right time of year. Our big screen projector and fire pit are two amenities you'll be sure to enjoy!
11 – 18 Jan
4.91 out of 5 average rating, 382 reviews
Guest favourite
Home in Bowling Green
Peaceful Country Cottage
Traveling for work or pleasure? Enjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Vandalia, Louisiana, Hannibal or Mark Twain Lake. (40 Min). About one hour from St. Louis.
30 Jan – 6 Feb
4.97 out of 5 average rating, 198 reviews

Popular amenities for Mark Twain Lake holiday rentals

Other great holiday rentals in Mark Twain Lake

Superhost
Bungalow in Macon
Charming 3 bedroom Bungalow
24 Nov – 1 Dec
4.88 out of 5 average rating, 277 reviews
Guest favourite
Guest suite in Clark
Woodland Fox Retreat
2 – 9 Aug
4.94 out of 5 average rating, 103 reviews
Guest favourite
Home in Quincy
❤️Quincy Quarters❤️
25 July – 1 Aug
4.94 out of 5 average rating, 219 reviews
Guest favourite
Place to stay in Columbia
*~Private Studio~ full bath & kitchenette
21 – 28 May
4.9 out of 5 average rating, 286 reviews
Guest favourite
Cabin in Perry
Mark Twain Lake Cabin at Cedar Crest Place
8 – 15 Apr
4.92 out of 5 average rating, 26 reviews
Guest favourite
Condo in Monroe City
Enjoy a getaway at Mark Twain Lake
11 – 18 Feb
4.84 out of 5 average rating, 43 reviews
Guest favourite
Condo in Monroe City
Lovely 2 Bed 2 Bath, Pet Friendly, Family Stay
30 Apr – 7 May
5.0 out of 5 average rating, 11 reviews
Guest favourite
Cabin in Monroe City
Mark Twain Lake Cabin
16 – 23 Apr
5.0 out of 5 average rating, 16 reviews
Superhost
Cabin in Perry
Cannon Dam Cabins - Poolside Family Cabin
27 May – 3 June
5.0 out of 5 average rating, 7 reviews
Guest favourite
Home in Paris
Grit & Grace Lodge near Mark Twain Lake
27 Oct – 3 Nov
4.99 out of 5 average rating, 67 reviews
Guest favourite
Home in Paris
House min. from MTL boat ramps
11 – 18 Dec
5.0 out of 5 average rating, 11 reviews
Superhost
Home in Perry
Kennedys' Red Barn Inn/6 beds/ Includes Breakfast
31 July – 7 Aug
4.83 out of 5 average rating, 23 reviews

Destinations to explore