Holiday houses in Santa Fe Lake

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Top-rated holiday rentals in Santa Fe Lake

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
A wooden dock extends over the water towards a two-story house, featuring a spacious patio with seating. The grassy area around the house is shaded by trees draped in Spanish moss, contributing to a serene outdoor environment.
Home in Waldo
4.97 out of 5 average rating, 33 reviews

Lake Santa Fe House Amazing Views Sunrise Sunset

Come make memories for a lifetime on Santa Fe lake in Earleton . This a great place to stay for Gator events with a 20 minute commute. The house is in a paved neighborhood for walking or biking. Enjoy beautiful sunrises and sunsets with your unobstructed lake view . The house is comfy and cozy for the whole family to come enjoy. Whether you are into water sports, fishing, or just want a nice quiet getaway this place offers it all. Right on lake, with your own private boat ramp, dock and beach

Superhost
Home in Melrose
5 out of 5 average rating, 4 reviews

Tranquil Lakehouse with Private Access

Welcome to a boater’s dream retreat in Melrose. Tucked inside a quiet cove, this peaceful lake escape is protected from wind and noise while offering incredible access for fishing and water sports. Launch from the private boat ramp, tie up at two docks, and clean your catch on site. This 3-bedroom, 2-bath home sits just 3 miles from Historic Downtown Melrose and is within easy driving distance of Gainesville. Perfect for families, anglers, and guests seeking a relaxed lakeside stay year-round.

Guest favourite
Two comfortable chairs are positioned on a wooden deck overlooking a calm lake, surrounded by a serene landscape. The expansive water reflects a blue sky, creating a peaceful atmosphere for relaxation and enjoyment.
Home in Melrose
5 out of 5 average rating, 22 reviews

Modern LAKE HOUSE on Lake Santa Fe near Gville/UF

Have fun OR relax at this fully renovated LAKE HOUSE w/BOATHOUSE and raised sunset deck only 30 mins to Gainesville! Sit back and and enjoy the beautiful views of the lake as soon as you enter the home or up close from the hammock swings in the boat house! 3 BR/2 BA plus converted air conditioned garage used as a game room with Ping Pong Table and TV, easily sleeping 8. The backyard offers a large deck with privacy fencing and lush landscaping with direct access to step right into the lake.

Top Guest favourite
A charming log home is nestled among large trees draped in Spanish moss, with a well-kept grassy area leading to the lake. The porch is visible, and the peaceful water serves as a backdrop, enhancing the natural beauty of the surroundings.
Cabin in Hawthorne
4.97 out of 5 average rating, 174 reviews

Charming Lakefront Log Home

Welcome to your perfect lake retreat! Located on a no public access lake. This charming log home has a private dock and boat ramp suitable for launching your boat for fishing or skiing. There are kayaks on premises for use. This is an ideal location to enjoy North Florida’s lake life with family, friends, or work retreat. Includes a fully stocked kitchen, covered porch, fire pit, gas grill, and WiFi if you feel the need to plug in. NOT suitable for parties or events. NO loud noise, please.

Top Guest favourite
A serene lakeside view features vibrant pink flowers and lush greenery framing a hammock. The calm, clear waters of the private lake are visible in the background, with two kayaks resting on the shore, creating an inviting space for relaxation.
Cottage in Hawthorne
4.97 out of 5 average rating, 201 reviews

Modern Cottage on Private Spring Fed Lake

Nestled on a gorgeous spring-fed private lake in the woods, our charming cottage is your ideal retreat. Whether you're dreaming of peace and quiet, a romantic getaway, or fun with your kids, this is the place to be! Kayak around the serene lake as you witness breathtaking sunsets, take a dip in the cool water or simply unwind amidst the beautiful surroundings. As night falls, gather around a fire and gaze up at the many stars lighting the sky. Come and create many cherished memories ☀️

Top Guest favourite
A modern kitchen features light cabinetry paired with dark lower units. A double sink is positioned beneath a window, allowing natural light. The turquoise tile backsplash adds a pop of color. Open shelving displays dishes, and a stainless steel stove is visible.
Apartment in Melrose
4.89 out of 5 average rating, 230 reviews

The Orchid of Lake Santa Fe

Melrose Bay on Lake Santa Fe This apartment is newly remodeled. It features new cabinets, new appliances, a private porch and lovely furnishings, WIFI and cable. Downtown Melrose is in walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store, dollar store and Ace. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, boating, skiing and fishing.

Top Guest favourite
Home in Melrose
4.96 out of 5 average rating, 53 reviews

August Awaits! Lily Pad -Lake, Swim, fish, hot tub

Our summer is filling up at The Lily Pad but August has some prime dates yet available. Summer is all about slowing down & soaking in lake life. Perfect for small families seeking peace & privacy, this relaxing lake cottage offers beautiful lake views, screened porches, hot tub, grills, games & inviting spaces to unwind after a day of boating, fishing, swimming, or nature. Enjoy 2 bedrooms & baths, full kitchen, & cozy living areas minutes from historic Melrose & close to Gainesville.

Guest favourite
A quaint cottage with blue exterior is shown, featuring a covered porch with a wooden walkway. The entrance is accented by large windows and a charming sign. Lush greenery surrounds the property, complemented by a clear blue sky above.
Cottage in Earleton
4.94 out of 5 average rating, 36 reviews

Lake Santa Fe Cottage Get Away (1 Room Studio)

Cozy, quiet space to relax and enjoy beautiful Lake Santa Fe. Perfect for a 2-3 day getaway. Spacious 1 room, 1 bath lakeside studio cottage at the historic former Buddy's Landing site on Lake Santa Fe in Earleton. Private and gated with direct lake access. A peaceful, quiet space to unplug and get away from the daily chaos. Use of the private boat launch for a small additional fee ($20). (Currently 6 cottages for rent. Perfect for multiple families to hang together on the lake!).

Top Guest favourite
Dome in High Springs
5 out of 5 average rating, 6 reviews

Soluna GeoDome 2: Stargazing, Springs, Outdoor Tub

Check out our latest handcrafted geodome creation. Tucked into the trees at Soluna Springs, 3 min to Poe, 5 min to Blue, and 12 min to Ginnie Springs, our geodome has everything you need to stay comfortable while being close to nature, and nothing you don’t. Rest on our King organic Birch mattress, stargaze while soaking in our outdoor tub, take a hot outdoor shower after the sauna, fire up the charcoal grill and fire pit, and sit back and relax. This isn’t a hotel. Its a reset.

Guest favourite
A figure glides across the water at sunset, creating ripples in the smooth lake surface. The sun casts a golden reflection, enhancing the serene ambiance. Soft clouds are visible in the sky, adding depth to the tranquil scene.
Cottage in Melrose
4.98 out of 5 average rating, 103 reviews

The Nest on Lake Santa Fe in Melrose, FL

The Nest is a beautiful two-story cottage on Lake Santa Fe. Enjoy some peace and serenity, catch monster bass, or bring your ski boat for high-speed fun. We are located just 20 minutes from Gainesville and UF. The Nest is great for a weekend getaway or a week of peaceful relaxation. We do not allow parties or events out of respect for our neighbors and we allow a maximum of 6 guests (max 4 adults). Absolutely no animals are allowed on the property at any time for any reason.

Top Guest favourite
A serene lakefront view features two kayaks and a canoe resting on sandy shores. A wooden dock extends into the calm waters, while fluffy clouds drift across a bright blue sky. Lush greenery surrounds the tranquil setting, creating a peaceful outdoor space.
Home in Keystone Heights
4.97 out of 5 average rating, 97 reviews

4/3 Lake House on Lake Geneva in Keystone Heights

Bring the whole family to this amazingly restored Florida lake home with lots of room for fun. Swim in the lake, catch some fish, build a sandcastle, make s'mores, nap in the sunroom, play fetch with your dog in the fenced yard, and so much more. Only an hour away from the beaches and the many springs of North Florida. The 1940's "Camp Blanding" house has had a complete makeover giving it the feel of an "Old Florida" lake house with all the comforts of modern living.

Top Guest favourite
A wooden dock extends over calm waters reflecting a vibrant sunset. Two Adirondack chairs are positioned atop the dock, offering a serene spot to relax and enjoy the view. The horizon showcases a blend of warm colors as the sun sets gently in the distance.
Apartment in Melrose
4.99 out of 5 average rating, 121 reviews

Lakefront Retreat Apartment Remodeled, Premium Bed

Private lake home on Big Lake Santa Fe is the perfect place to unwind and enjoy gorgeous sunset views. The rental unit is an upstairs separated apartment. It has a cedar interior with a cabin feel that has been renovated with new appliances, flooring and updated bathroom with walk in shower. Bring your boat to cruise the lake or fish and tie up at our dock. Enjoy swimming, water skiing, fishing or just relaxing on the deck.

Popular amenities for Santa Fe Lake holiday rentals

  1. Airbnb
  2. United States
  3. Florida
  4. Alachua County
  5. Santa Fe Lake