Guesthouse accommodation & holiday rentals in Frederick County
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Top-rated Guesthouses in Frederick County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Frederick County guesthouses
Family-Friendly guesthouses
Guesthouse in Middletown
4.95 out of 5 average rating, 247 reviewsIndulge, Fresh Flowers, Frederick County Haven
5 – 12 Apr
Guesthouse in Frederick
4.97 out of 5 average rating, 316 reviewsThe Shady Bear Cabin
16 – 23 Feb
Guesthouse in Smithsburg
4.97 out of 5 average rating, 645 reviewsJewel Vinsota Artist's Guesthouse
3 – 10 Feb
Guesthouse in Frederick
4.98 out of 5 average rating, 161 reviewsPool and Heated Spa Open April 1st
21 – 28 Jan
Guesthouse in Frederick
4.86 out of 5 average rating, 29 reviewsThe Wander Inn
28 Sept – 5 Oct
Guesthouses with a patio
Guesthouse in Middletown
Simple gestures
24 Nov – 1 Dec
Guesthouse in Boonsboro
New place to staySRV Room @Music House. Please Read Half Bath only
19 – 26 Jan
Guesthouse in Lovettsville
4.94 out of 5 average rating, 122 reviewsThe Patent House
24 Apr – 1 May
Guesthouse in Myersville
4.93 out of 5 average rating, 192 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
13 – 20 July
Guesthouse in Mount Airy
4.99 out of 5 average rating, 77 reviewsTreasured Hideaway on the Hill
24 Sept – 1 Oct
Guesthouse in Middletown
5.0 out of 5 average rating, 92 reviewsCottage, Pool, & Breakfast on 100ac Horse Estate
22 – 27 July
Guest house rentals with a washing machine and dryer
Guesthouse in Middletown
4.95 out of 5 average rating, 247 reviewsIndulge, Fresh Flowers, Frederick County Haven
5 – 12 Apr
Guesthouse in Myersville
4.93 out of 5 average rating, 192 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
13 – 20 July
Guesthouse in Smithsburg
4.97 out of 5 average rating, 645 reviewsJewel Vinsota Artist's Guesthouse
3 – 10 Feb
Guesthouse in Frederick
4.98 out of 5 average rating, 161 reviewsPool and Heated Spa Open April 1st
21 – 28 Jan
Guesthouse in Frederick
5.0 out of 5 average rating, 234 reviewsThe Carriage House at Hessian Overlook, Downtown
28 Sept – 5 Oct
Guesthouse in Frederick
4.86 out of 5 average rating, 29 reviewsThe Wander Inn
28 Sept – 5 Oct
Guesthouse in Frederick
5.0 out of 5 average rating, 77 reviewsA Quiet Haven
18 – 25 Nov
Guesthouse in Mount Airy
4.99 out of 5 average rating, 77 reviewsTreasured Hideaway on the Hill
24 Sept – 1 Oct
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