
Apartment holiday rentals in Cape Girardeau
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Cape Girardeau
Guests agree: These apartments are highly rated for location, cleanliness and more.

Cozy & Comfortable 1 Bedroom Suite
This cozy, beautifully furnished suite is the ideal retreat for a single traveler or couple looking for comfort and convenience. The open floor plan includes a spacious living room with comfy seating and an Amazon Fire TV, perfect for streaming your favorite Netflix or Prime Video shows. The fully equipped kitchen features a coffee bar with both a 12-cup carafe and single-serve Keurig pods, ensuring your mornings start off right. The bathroom is spacious with a tub/shower combo and a large vani

Beautiful Historic Boulevard District Apartment
This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Regal Rustic Retreat
Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

Historical Kage House
The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

Unique Design | Walk Downtown/River | .5 mile SEMO
At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Mayberry Retreat
This unique place has a style all its own. Come enjoy our 2 bed (king and queen), one bath vacation unit, where you can slow down and enjoy what’s close by : wine trail, hiking the little Grand Canyon, Giant City and other Shawnee National forest sites; fishing or floating the many lakes; shopping local for antiques or visiting the university. Major cities nearby- St Louis, Cape Girardeau, and Paducah KY. No pets. No smoking in the unit. Trains run past and nearby. Maximum 4 people stay:)

Downtown Penthouse w/ Amazing River View!
AMAZING RIVERVIEW Plus Close to Downtown Cape? Our Airbnb is the best place to be! Relax in our Roof Deck after going around downtown and ENJOY THE VIEW. Located in a safe and quiet neighborhood plus it is WALKING DISTANCE from everything! It features a roof deck with (by far) the best view in Cape, enough space for six to sleep (two queen beds and two couches), one off street parking spot and a building with secure entry. Plus we just live across the street if you need anything.

The Outlook - Private Balcony
Welcome to 115 N Water, Unit 103 in Cape Girardeau, MO! This delightful property not only offers a cozy retreat but also boasts a private balcony with stunning, unobstructed views of the Mighty Mississippi River. Perfectly situated close to downtown, it's just steps away from a vibrant nightlife scene, with numerous bars and restaurants for an unforgettable date night experience. Enjoy the best of both worlds – scenic beauty and lively entertainment – right at your doorstep!

Visit the "Gone Girl" neighborhood
Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

Fresh & Cozy Retreat w/ King Bed · By KeenStays
This fresh apartment offers a unique blend of chic style and cultural charm, nestled in a freshly rehabilitated building in Downtown Cape Girardeau. Enjoy a vibrant stay by being in walking distance to shopping, dining, and downtown entertainment! The apartment features a spacious, light-filled layout with chic finishes and appliances. Enjoy a comfortable & spacious living area. Don't forget to visit the viral mac & cheese bar, Roni's, downstairs!

Downtown 4BR with 2 King Beds! Off-street parking
- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance
Popular amenities for Cape Girardeau apartment rentals
Weekly apartment rentals

2 Bed Room Downtown carbondale

Location, Location, Location!

Lakefront, dog-friendly studio cabin with porch

Modern 2BR Apt w Electric Fireplace · By KeenStays

The Lab! Come stay in our brand new space.

Emonyah blue bottom apartment

INN Keepers Quarters

Rivers Dawn- Historic Home - River View - King Bed
Private apartment rentals

Walking Distance to Campus, Food & Entertainment!

Gail's Corner Window- River View

Private Nurse Retreat 2 + Walk to SEMO Activities!

2Bdrm Stay in Downtown Cape | Walkable, Laundry

Downtown Retreat

Modern Boho Getaway · 1BR Apartment · By KeenStays

Private Nurse Retreat 1 + Walk to SEMO Activities!

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays
Family-friendly apartment rentals

Studio Downtown Carbondale

DownTown Carbondale 2

*Magnolia Inn* Rv/boat parking!

Modern Studio Apt

Extended stay DownTown Carbondale

Lennon's Garden 2BR with KING bed, Carterville

Quiet lakeside retreat for 2!
When is the best time to visit Cape Girardeau?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $189 AUD | $173 AUD | $176 AUD | $194 AUD | $200 AUD | $200 AUD | $202 AUD | $200 AUD | $185 AUD | $183 AUD | $193 AUD | $173 AUD |
| Avg. temp | 1°C | 4°C | 9°C | 14°C | 20°C | 25°C | 26°C | 25°C | 21°C | 15°C | 8°C | 3°C |
Quick stats about apartment rentals in Cape Girardeau

Total holiday rentals
Explore 30 holiday rentals in Cape Girardeau

Nightly prices starting at
Cape Girardeau holiday rentals start at $62 AUD per night before taxes and fees

Verified guest reviews
Over 2,350 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
30 of Cape Girardeau holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Cape Girardeau rentals

4.9 Average rating
Cape Girardeau stays are highly rated by guests—averaging 4.9 out of 5!
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