Apartment holiday rentals in Cape Girardeau

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Regal Rustic Retreat

Take it easy at this unique and tranquil getaway. Close to SIU Carbondale and also Murphysboro. We offer a quiet, simple apartment to relax and recharge. Free local over the air television. We have broadband/smart monitor for your HDMI stick . Bring your own Roku or Firestick with your subscriptions. The second bedroom is an open loft area, not a separate room. We offer a large storage space for bicycles and mudroom with washer/dryer for cleaning up after a hike or bike race. Full kitchen.

Historical Kage House

The Building is reminiscent of eighteenth-century New Orleans architecture, and was built sometime before 1883. The Kage House is located at 120 Broadway in the historical district and is less than a minutes walk to Main Street and less than a 10 minutes walk to the Isle of Capri Casino. On Main Street you will find many fine shops and restaurants, or just enjoy the scenic area as you walkabout. This is by far one of the best places in Cape. Additional reviews can be read on the VRBO website.

RiverSide Barn Suite on the Mississippi River.

The barn suite is a beautiful 2 bedroom apartment overlooking the Mississippi River and housed in a unique barn with its own separate entrance. The deck views are spectacular and takes sitting and relaxing to a new level. Our wine place “The RiverHouse “ is within walking distance with the best worldwide wines and menu in the area. www.theriverhousewineplace.com We are 12 minutes from Cape Girardeau and serviced by Lyft & Car-Go. You May contact us by text or call and available at any time.

Modern 2BR Apt w Electric Fireplace · By KeenStays

Experience luxury living in the heart of downtown Cape Girardeau right on Broadway with this stunning apartment nestled above the beautifully rehabbed Broadway Theater. Features spacious, open-concept layout with high-end finishes throughout! Enjoy cozy living spaces complete with electric fireplaces. Located on iconic Broadway Street, you’ll have direct access to shopping, dining, and downtown events, making this a prime oasis. Complete with a bourbon lounge below and bistro next door!

Riverside Getaway | Near Campus & Downtown

Experience early-1900s architecture just steps from Cape Girardeau’s riverfront. This historic home blends original character with modern updates for a comfortable, well-located stay. Tall ceilings, classic trim, and natural light create a warm feel, while reliable Wi-Fi and updated finishes make it practical for weekend visits or longer stays. Whether you’re here for the Riverwalk, a campus event, or time downtown, this retreat offers charm and walkable convenience.

The Windbreak

Forget your worries in this spacious apartment, the lower/first level of a 3-level house, a peaceful place at the woodsy end of a country lane, not far from two state parks, five lakes, wine trail, Southern Illinois University and other interesting features of this area. The 1st level apartment is large, has a kitchen, dining room, 2 bedrooms, living room/bedroom, a full bath, and a utility room, 2 exterior doors, one to a patio with a fire pit and charcoal cooker.

Downtown 4BR with 2 King Beds! Off-street parking

- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

Lovely 2 bedroom apartment with luxury shower.

This special home away from home has 800 sq. ft. and is on 1st floor. Less than one mile from grocery, a few eateries and park. There is little traffic on our one-block street with an old graveyard across the street. We are just minutes away from a beautiful lake and rivers. Explore historic sites, visit antique shops and enjoy fishing, kayaking, hunting, visiting family or just relaxing.

River View Loft, Walk to Downtown

This cozy upstairs loft is just steps from Downtown Cape Girardeau, offering stunning views of the Mississippi River, Bill Emerson Memorial Bridge, and historic district homes. Enjoy peace and quiet, with the vibrancy of downtown just a short walk away. Perfect for those seeking a relaxing retreat with easy access to the area's best attractions. Ideal for both relaxation and exploration!

Modern Queen Suite Near SIU Carbondale

Stay in Suite 3 at Wall Street Suites, a modern queen suite near SIU Carbondale. This newly renovated micro-suite blends industrial charm with stylish urban design. Enjoy a full kitchen, Smart TV, queen bed & updated bath, plus a shared lobby workspace. Perfect for mid-term or monthly stays near SIU East Campus. Note: Access via stairwell.