Holiday houses in Byron

5 out of 5 average rating, 96 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Fully fenced backyard.

FamilyLocationCheckout

4.91 out of 5 average rating, 56 reviews

A bell-shaped canvas tent is positioned on a gravel surface amid lush greenery, surrounded by tall trees. Soft sunlight filters through the leaves, casting gentle shadows on the tent, which is secured with ropes. The natural setting enhances the sense of privacy and tranquility.

Tent in Mantorville

Glamping in the Minnesota Woods

Hidden Springs Hideaway is a little oasis, nestled in the woods. Located in southeastern Minnesota's driftless region, where you are surrounded by rolling green hills, the Zumbro River and limestone bluffs. Only a half-mile to the quaint town of Mantorville (some call it the Stars Hollow of Minnesota) where you'll find a cute coffee shop, antique stores, a breakfast spot in an old school house, a park on the river, a restaurant built in the 1850s and a saloon with drinks and live music.

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The modern kitchen features light wood cabinetry, stainless steel appliances, and a spacious island with a gas stove. Natural light filters through a window above the sink, creating a bright and inviting workspace. A dining area is seen in the background, adding to the open layout.

4.94 out of 5 average rating, 105 reviews

XLarge 2 bed 2 bath with rec room near Mayo

Room to spread out! Entire house to yourself, near Mayo Clinic, Single Family Home. Modern 2 bedrooms, 2 baths, kitchen, dining room, beautiful living space and rec room. Amazing quiet location on dead end street near park, excellent restaurants, shopping and Mayo Clinic. Unpack and unwind with choice of shade or sun patio, abundance of walking trails & exercise equipment. All the amenities to cook and launder, we have you taken care of. We look forward to welcoming you to Rochester!

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A welcoming book titled 'Welcome to Oasis' is displayed prominently, featuring a lotus flower design and neatly placed beside a decorative white vase. Greenery is visible in the background, adding a touch of nature to the inviting setting.

4.95 out of 5 average rating, 148 reviews

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

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4.98 out of 5 average rating, 46 reviews

Near Mayo Family Friendly / 5 beds 2 baths CLEAN

Nestled in the cul-de-sac of Arcon Lane in the northwest side of Rochester, Minnesota, an Airbnb was established in the summer of 2025. It was given a name called Arcon Hollow B&B. Arcon Hollow B&B can be whatever space you’d like it to be for your stay. It can be your peace and quiet space away from the chaos of life, your rest and restore atmosphere to renew your energy, or your home away from home for different reasons that bring you to our beautiful town Rochester, Minnesota.

FamilyValueSleep quality

4.98 out of 5 average rating, 87 reviews

The Don

Modern, Accessible Retreat | Step-Free, Pet-Friendly, Comfort for All Welcome to your home away from home! This stylish, fully renovated, and accessible 3-bedroom, 1-bathroom home is designed with comfort and inclusivity in mind. Whether you're traveling with a wheelchair, walker, or simply prefer a step-free experience, we've got you covered. We welcome all guests and are happy to answer any questions about the space or specific needs you may have!

ValueFamilyTV

4.97 out of 5 average rating, 109 reviews

The exterior of a cottage is showcased, featuring a combination of wood and stone accents. A welcoming front door is framed by large windows, and a decorative wreath adds a touch of charm. A well-maintained grassy area surrounds the entrance, complemented by vibrant trees.

Tiny home in Rochester

Downtown Cottages | 5 Blocks From Mayo | No Stairs

Welcome to our Downtown Cottages, Rochester’s First "Tiny Homes" : 3 min drive/10 min walk to the Mayo Clinic Campus. Experience our four charming cottages- Enjoy zero-entry, slab-on-grade living with NO stairs!! Elegantly furnished and fully stocked, each unit also includes off-street parking. Located just 5 blocks from the downtown Mayo Clinic Campus, our cottages offer the perfect blend of comfort and convenience. Book your stay today!

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4.97 out of 5 average rating, 105 reviews

The unique grain bin structure is displayed, featuring a rounded shape with a metallic exterior. A wraparound deck is visible, supported by slender black railing, while large windows allow light to fill the interior. The property is surrounded by lush green fields under a clear blue sky.

Farm stay in Wykoff

Bin There, Done That (and Pickleball too!)

Bin There, Done That inspiration came from the television series "Texas Flip N Move." During one episode, an old grain bin was moved and repurposed into a home and from that Bin There, Done That was born. Here you will find a place to relax and refresh, a farming community surrounded by nature, good eateries, and local artisans. You can enjoy a variety of experiences and at the end of your stay you can say, "I've Bin There, Done That."

LocationFamilyCheckout

4.87 out of 5 average rating, 440 reviews

single level Home/ 5 min to Mayo/fenced yard

Peaceful single-level home near Mayo Clinic with comfortable beds, a fully equipped kitchen, fast Wi-Fi, three smart TVs, a private fenced yard with patio, and a variety of indoor and outdoor entertainment options. Conveniently located near the Mayo Clinic campus and Rochester’s main attractions, this rollator-accessible home is ideal for families. We strive to accommodate flexible check-in/check-out arrangements whenever feasible.

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4.97 out of 5 average rating, 179 reviews

You’re home! St.Augustine MAYO CLINIC garage!

Time to relax! 2 car Garage Parking (a Minnesota must!) Fast WiFi, smart tv! Washer and Dryer and dishwasher! Clean comfortable home in a great SAFE neighborhood convenient to everything. Recliner! Costco, the best grocery’s stores, bars, restaurants, and movie theaters 1 min away. Minutes from the Mayo Clinic! Quick and easy drive! Check out my other listings to see the 5 Star reviews!

ValueFamilyComfort

4.79 out of 5 average rating, 14 reviews

Villa in Rochester

1st Premium Luxury Rooftop Stay w/ Elevator

Experience family fun in this stylish new model home featuring four bedrooms and four bathrooms. Enjoy a rooftop patio, an elevator, and a spacious primary suite with stunning views. The elevator provides easy access to all levels, making grocery trips a breeze from the two-car garage. Conveniently located just 12 minutes from the Mayo Clinic, this home showcases luxurious finishes throughout.

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A modern kitchen is showcased with an island featuring a light wood countertop. Stainless steel appliances, including a refrigerator, are visually prominent. A cozy living area is visible with a dark sofa, illuminating natural light from a large front window. A dedicated laundry area is seen to the right.