Guesthouse accommodation & holiday rentals in South Carolina
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Top-rated Guesthouses in South Carolina
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
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Popular amenities for South Carolina guesthouses
Family-Friendly guesthouses
Guesthouse in Salem
4.88 out of 5 average rating, 291 reviewsMountain Edge Loft
Guesthouse in West Columbia
4.94 out of 5 average rating, 607 reviewsCarriage House: Studio Bed & Bath - Pool & Hot Tub
Guesthouse in Townville
4.88 out of 5 average rating, 232 reviewsLisa’s Lodge
Guesthouse in Greenville
4.92 out of 5 average rating, 592 reviewsHistoric 19th Century Cabin/Guest House
Guesthouse in Beaufort
4.94 out of 5 average rating, 400 reviewsMeridian Rd. Guest House Walk to Restaurants/Parks
Guesthouse in Charleston
4.92 out of 5 average rating, 311 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Pawleys Island
4.95 out of 5 average rating, 224 reviewsPrivate Studio Apt - (Pets/beach/pool/golf)
Guesthouses with a patio
Guesthouse in Abbeville
4.95 out of 5 average rating, 110 reviews1-bedroom guesthouse in Abbeville, SC
Guesthouse in Charleston
4.93 out of 5 average rating, 179 reviewsQuaint Cottage Studio in Ashley Forest (Avondale)
Guesthouse in Charleston
4.96 out of 5 average rating, 133 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Johns Island
4.91 out of 5 average rating, 115 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Charleston
4.98 out of 5 average rating, 130 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Columbia
4.95 out of 5 average rating, 151 reviewsRenovated One Bedroom Guest House by UofSC
Guesthouse in Spartanburg
5.0 out of 5 average rating, 46 reviewsThe Lodge at Pythian Park
Guesthouse in Pawleys Island
4.96 out of 5 average rating, 83 reviewsThe BELLA at Hagley Landing Boating Beach Golf
Guest house rentals with a washing machine and dryer
Guesthouse in Westminster
4.99 out of 5 average rating, 151 reviewsLit'l Bit O' Heaven- Rocky Top Lodge
Guesthouse in Camden
4.91 out of 5 average rating, 279 reviewsCamden Coach House Long term stay southern balance
Guesthouse in Donalds
4.99 out of 5 average rating, 347 reviewsHome on the farm
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 413 reviewsGuesthouse Convenient to Charleston, Shem Creek, and Beaches
Guesthouse in Florence
4.99 out of 5 average rating, 682 reviewsBoho Private Downtown Stay Near I-95 & Hospital
Guesthouse in Abbeville
4.99 out of 5 average rating, 150 reviewsModern Carriage House
Guesthouse in Bluffton
4.97 out of 5 average rating, 459 reviewsCharming Carriage house
Guesthouse in Summerville
4.97 out of 5 average rating, 221 reviewsTiny Oak Cottage in Historic Downtown Summerville
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