Guesthouse accommodation & holiday rentals in San Diego
Find and book unique guesthouse accommodation & rentals on Airbnb
Top-rated Guesthouses in San Diego
Guests agree: These guesthouses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouses
Family-Friendly guesthouses
Guesthouse in San Diego
4.92 out of 5 average rating, 246 reviewsNorth Park Garden Studio
Guesthouse in Chula Vista
4.95 out of 5 average rating, 482 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in San Diego
4.77 out of 5 average rating, 887 reviewscharming, colorful, close to beach
Guesthouse in San Diego
4.97 out of 5 average rating, 514 reviewsCentral & Serene Secret Garden Guesthouse
Guesthouse in San Diego
4.9 out of 5 average rating, 119 reviewsSoCal Tiny Home, Heart of South Park
Guesthouse in San Diego
4.97 out of 5 average rating, 298 reviewsPrivate Guest House with a View
Guesthouse in San Diego
4.91 out of 5 average rating, 387 reviewsNorth Park Cottage
Guesthouse in San Diego
4.95 out of 5 average rating, 484 reviewsRomantic Private Garden Studio Near Downtown
Guesthouses with a patio
Guesthouse in Lakeside
4.94 out of 5 average rating, 106 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in San Diego
4.92 out of 5 average rating, 156 reviewsCentral studio w/ private outdoor space & parking
Guesthouse in La Mesa
4.98 out of 5 average rating, 257 reviewsLa Mesa Suite
Guesthouse in San Diego
4.96 out of 5 average rating, 108 reviewsCozy Urban Casita! Near Gaslamp, Zoo and Coronado
Guesthouse in San Diego
4.99 out of 5 average rating, 155 reviewsAdorable cottage in Talmadge
Guesthouse in La Mesa
4.97 out of 5 average rating, 139 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Guesthouse in National City
4.9 out of 5 average rating, 102 reviewsPrivate Studio ONLY 4 Miles to SD Gaslamp Quarter!
Guesthouse in San Diego
4.99 out of 5 average rating, 115 reviewsModern Guest House with Patio, Parking, & Laundry
Guest house rentals with a washing machine and dryer
Guesthouse in San Diego
4.96 out of 5 average rating, 112 reviewsRelax in a Centrally Located, Modern Guest House
Guesthouse in San Diego
4.95 out of 5 average rating, 299 reviews*BEAUTIFUL* Sunny Home in Golden Hill
Guesthouse in San Diego
4.95 out of 5 average rating, 113 reviewsAdorable studio/private entrance/reserved parking
Guesthouse in San Diego
4.88 out of 5 average rating, 424 reviewsThe Golden Hill mosaic "casita"
Guesthouse in San Diego
4.95 out of 5 average rating, 122 reviews1BR Casita in the Heart of Kensington!
Guesthouse in San Diego
4.95 out of 5 average rating, 218 reviewsPrivate beach guesthouse w/ private parking
Guesthouse in San Diego
4.98 out of 5 average rating, 120 reviewsCasita Hermosa - Close to everything in San Diego
Guesthouse in San Diego
4.99 out of 5 average rating, 135 reviewsCarrie’s North Park Casita, in Heart of San Diego
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
Destinations to explore
- Tijuana Holiday rentals
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