Hotels in Vaca Key

Find and book unique hotels on Airbnb

Top-rated hotels in Vaca Key

Guests agree: these hotels are highly rated for location, cleanliness and more.

%{current} / %{total}1 / 1

A bright and airy room measuring 300 sq. ft. features two spacious beds with soft linens. A large window offers views of palm trees outside. Warm wood furniture, including a desk and chair, complements the light decor. A flat-screen TV and coffee machine are also included.

Hotel room in Marathon

5 out of 5 average rating, 3 reviews

Tropical Stay with Palm Trees & Beach Breezes!

Experience an unforgettable stay by the waterfront, where vibrant local adventures await. Proximity to Turtle Hospital offers a unique wildlife encounter, and a short drive leads you to the historic Seven Mile Bridge. Adventure lovers can explore diving, swimming, and biking, while those seeking relaxation can enjoy beachside serenity. With the Marathon Airport nearby, your getaway in the heart of the Florida Keys promises convenience and excitement.

Fisher Inn Resort & Marina

4 out of 5 average rating, 28 reviews

Fisher Inn Resort & Marina

Deluxe two queen room invites you to enjoy a deluxe life with a well equipped kitchenette featuring a full size refrigerator freezer two burner stove top coffee maker microwave and cooking utensils unwind in comfort with a small table chairs and a cozy corner chaise sofa modern amenities include air conditioning blackout curtains HD channels and an ihome alarm clock radio every detail is designed for relaxation and convenience during your stay.

A spacious guest room features a large bed with light bedding and a comfortable seating area with a sofa. Colorful artwork adorns the walls, complemented by side tables with lamps. A television sits on a wooden console, while a patterned rug adds texture to the floor.

Hotel room in Marathon

Cozy Studio in Marathon

This stylish and unique place sets the stage for a memorable trip. Situated just off the historic Florida Keys Overseas Highway, The Hammocks at Marathon, lets you and your family experience the best of the Florida Keys with each stay. The resort entrance envelops you in lush tropical foliage, and Caribbean music greets you at the door. Kick off your shoes and throw on your flip-flops. Enjoy every waking moment in the Sun!

Hadley House

4.37 out of 5 average rating, 52 reviews

Hadley House

Standard room on the main level welcomes you with two queen beds and a cozy space for relaxation enjoy the convenience of a microwave mini fridge coffee maker and cutlery along with a table and chairs for meals or conversation each room is unique but includes all the same thoughtful amenities unwind and make the most of your stay in comfort.

An outdoor swimming pool is surrounded by palm trees, with lounge chairs and umbrellas arranged neatly around its perimeter. The pool reflects the sky's colors while the sandy beach and ocean are visible in the distance, creating a serene beachside environment.

Hotel room in Islamorada

5 out of 5 average rating, 3 reviews

Ideal Mix of Comfort & Value! Free Parking/ Pool

Escape to Amara Cay Resort in Islamorada, where breezy island flair meets boutique elegance. Enjoy private beach access, zero-entry pool with hammocks, and coastal-chic rooms with balconies. Explore kayaking, snorkeling, or hop a water taxi for dining across sister resorts—ideal for couples, families, or relaxed getaways.

Guest favourite

A bright and inviting room features a spacious bed with crisp white linens, accompanied by a wooden headboard. A ceiling fan provides airflow, while a small dining table and chairs are situated nearby. A kitchenette with a refrigerator and microwave is also visible.

Hotel room in Marathon

4.86 out of 5 average rating, 51 reviews

Knight's Key Suites Deluxe King

One-of-a-kind place accommodations located next to the 7-Mile Bridge in the heart of the Florida Keys. These rooms feature 1 King-size bed that can accommodate up to 2 people with private bath, refrigerator and microwave. Enjoy our swimming pool from dawn until dusk. We are located next to the Sunset Grill and Raw Bar

Hotel room in Marathon

Oceanfront Balcony 2 Queen, Isla Bella, 5 Pools

Welcome to your ultimate oceanfront escape, perfectly located in the heart of the Florida Keys. Here, you are in the prime location for spectacular sailing, world-class fishing, snorkeling, and diving, not to mention the proximity to Sombrero Beach and the iconic Seven Mile Bridge.

A private balcony features two comfortable chairs and a small table adorned with decorative fruit. Lush palm trees sway in the gentle breeze, framing the scenic view of the beach and ocean just beyond the railing.

Hotel room in Islamorada

4.57 out of 5 average rating, 7 reviews

Ocean View Guest Room, 1 King, Balcony

Escape to Three Waters Resort & Marina in Islamorada, where the Atlantic, Gulf, and Florida Bay converge. Relax in island-chic rooms. Enjoy three pools, beaches, oceanfront dining, a full marina, and a water taxi to sister resorts—perfect for fishing, romance, or outdoor adventure.

A serene view of the ocean at sunset, with vibrant hues reflecting on the water's surface. Palm trees border a spacious area leading to a dock, while a pool area is visible, complete with lounge chairs and umbrellas, inviting relaxation.

Hotel room in Layton

4.67 out of 5 average rating, 21 reviews

Tranquil Island Studio - Perfect for Relaxation

Experience captivating sunsets and unbeatable relaxation at our award-winning retreat in the heart of the Florida Keys. Enjoy kayaking, paddle boarding, and fishing, plus stunning Gulf views and close proximity to local attractions. Join us for a memorable island getaway!

Hotel room in Islamorada

4.67 out of 5 average rating, 81 reviews

Picturesque Villa Near History of Diving Museum

Discover your home away from home in the Florida Keys. Come enjoy pristine beaches, heart-racing water sports, and stunning sunsets. Nearby, discover must-see spots like the History of Diving Museum and Theater of the Sea, all within easy reach.

A spacious sleeping area is highlighted by a large bed with crisp white linens. Natural light filters through latticed windows, illuminating the room. Two framed photographs adorn the walls, and a wooden side table complements the decor. A door leads to an outdoor area.

Hotel room in Islamorada

5 out of 5 average rating, 3 reviews

Jungle Suite @ Casa Morada

The Jungles Suite is the largest suite in the Garden House featuring an indoor jacuzzi tub and a large terrace that overlooks the garden. You’ll love the stylish decor of this charming place to stay.

An entrance to the property is framed by palm trees and tropical foliage. A covered archway leads into the driveway, with a pathway lined by rocks and greenery. The sun shines brightly, highlighting the clear blue sky.

Hotel room in Marathon

4.38 out of 5 average rating, 16 reviews

Kingsail Resort Apartment 102

Located central to all of what Marathon has to offer, just a quick drive down to Key West, Onsite dock and boat slips available, all the comforts of home with the amenities of a hotel