
Hotel holiday rentals in St. Charles County
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Top-rated hotels in St. Charles County
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Popular amenities for St. Charles County hotels
Family-Friendly hotels

Midwest Guest Room "E"
The room was perfect for what I needed. Very simple but definitely worth the price. It was nice to come back to a quiet place after working doubles and being able to relax and sleep.

King Redwood Bedroom at BnB in CWE!
Brandon and Sam’s Place was perfect for us it was close to the city. It was easy to take Ubers. we loved walking down the street to Whole Foods. There was also a beautiful Catholic cathedral with mosaics that we went to go explore around the corner Their place was so homey it felt like we were staying with family!! It was very peaceful and quiet. The bed was so comfortable and cozy! I honestly can’t wait to come back. Brandon and Sam are very generous. We enjoyed a bagel one morning!

Blue Spruce Room Queen Bed at BnB in CWE!
Great stay, second time in this location, will be interested in coming back

Midwest Guest Room "A"
This placed worked perfectly for us. It was close to where we needed to be, and also close to restaurants and other businesses. The room we stayed in was clean, had comfortable beds and good water pressure in the shower. We'll definitely be coming back to visit and this will be our first choice in lodging. Thank you!

Midwest Guest Room "C"
This place is perfect for us every time we come to Wentzville. The campus setting is peaceful, and the location is handy to the places we love to visit.

Midwest Guest Room "H"
This place was exactly what I needed for a quiet work location. The room was spacious, and the stay was quiet, without interruption, allowing me to get much-needed work done. The bed was comfortable, and the two large desks allowed me plenty of room to spread out. The wifi worked well for my needs. I would definitely stay here again for a quiet work time or a much-needed retreat from hectic daily life.

Evergreen Room Queen Bed at BnB in CWE
We really enjoyed this Airbnb! They had such clear instructions both in the bathroom and kitchen - I wish more Airbnb’s were that thorough.

Midwest Guest Room "D"
Cool dorm room style stay with full kitchen in hall way
Hotels with a pool

Home Away From Home | Free Airport Shuttle
Thank you so much, the room was cozy and clean, and everything went smoothly with check-in and check-out!!

St. Louis Suite l Swimming. Gym. Free Breakfast.
Enjoyed my stay, will certainly be back!

Downtown Studio l Swimming. Gym. Free Breakfast.
Prefect area, next view from the room, front desk staff was nice and helpful, breakfast there was good and they had a lot of food out. Will be staying here again.

Perfect Getaway Near The Airport | Free Breakfast
Nice place and good service room, good restaurant and food but the waitress wasn't friendly but I had a great experience besides that

Luxury Queen Room Near Airport | Free Shuttle
Hotels with a patio

Lovely spacious 2 room King suite, super quiet
I'm a repeat visitor at Tim's. I have occasional work in the area and appreciate that his place is so close to my destination. The place is clean and comfortable. Appliances are all new. Wifi was solid for me to stream a show and maintain fast remote connection to my client's site for after hours work. There's Aldi's grocery a few blocks away so I shop and eat in for time and cost savings. Tim is super responsive, always helpful.

#3 Betty Bloomer Le Velo Inn
We really enjoyed our stay at Le Velo in one of their well-appointed suites. The finishes and furnishings were the nicest of any Airbnb we had stayed in before and it was obvious that much care went into creating a really special space for guests (heated seat toilet/bidet was my personal favorite). We love the historical aspect of the entire place (being an original boarding house from the 1800s) as well as the historical theme of the particular room and how much effort was made to reflect that (Parisian chandelier, reuse of vintage doors, etc.) Logistically, it was very easy to get in and out. It was a great location in the Frenchtown part of Old St. Charles, which is a quieter, less developed historical area, but a short 10 minute walk from busier Main St. Area was quiet and safe and still had very close walking options for coffee/breakfast/pizza. And the outdoor lounge area was really nice even though we didn’t make use on this stay. Would love to come back again!

#4 – Penny Farthing Le Velo Inn
It was an absolute joy. My fiancee and I booked at this location in Saint Charles on a whim because we were going horse back riding out in High Ridge. It was the first time either of us experienced St Charles and we loved it so much, we are talking about moving there. It is such a beautiful little town with all types of local restaurants and shops and plenty to do all within walking distance. The Velo Inn was perfect as well. It is so unique and beautiful. EXACTLY as described in the listing/pictures. 10/10 we will for sure be back in the future. My 1 and only minor issue was the cost. But on the other hand, you can see the amount of work and effort they put into making this hotel a wonderful experience for their guests.

Napoleon's Retreat Burgundy Room
Really enjoyed the place. We had a couple of questions that were quickly and clearly answered. Strongly recommend!

1st Capitol Mansion - Suite 302
We had a wonderful stay at Jon’s charming vintage home! It has all the nostalgic charm of a classic college apartment—think character, cozy vibes, and personality—but with the added bonus of thoughtful renovations, true cleanliness, and modern comforts. One of our favorite features was the beautiful wooden staircase accented by a lovely stained glass window—it made every trip upstairs special. The price was very reasonable, especially for the quality of the space, and Jon was a friendly, attentive host who made sure everything was just right. Highly recommend if you're looking for something unique, welcoming, and budget-friendly!

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
This place is even more beautiful in person. It felt safe and clean. We will be back in the future.

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
This is a hidden gem that is maintained exceptionally well. The check in was smooth and the owners are very friendly. Only time we saw them was when we checked in and they gave us a tour of the place. The entire property is squeaky clean and provides every comfort offered in a five star hotel. I've stayed in many five star hotels across the world (Ritz Carlton, Four Seasons, Waldorf Astoria) and this is arguably better than those places given the unique experience it offers and the character of this place. I would definitely recommend this to anyone looking for a unique experience in St. Louis. It is also located in close proximity to a lot of local attractions.

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
Absolutely wonderful stay! Had a kitchen for use! Also was very thoughtful and had random necessities for use if you forgot yours during travel! Very beautiful and would definitely stay again!!!
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- Busch Stadium
- Six Flags St. Louis
- Saint Louis Zoo
- Central West End
- Enterprise Center
- Gateway Arch National Park
- Missouri Botanical Garden
- City Museum
- St. Louis Aquarium at Union Station
- Cuivre River State Park
- Pere Marquette State Park
- Meramec State Park
- Saint Louis Science Center
- The Winery at Aerie's Resort
- Castlewood State Park
- Cathedral Basilica of Saint Louis
- St. Louis Country Club
- Norwood Hills Country Club
- Missouri History Museum
- Grafton Winery the Vineyards
- Hidden Valley Ski Resort
- Adventure Valley Zipline Tours and Paintball Park
- Boone Valley Golf Club
- Raging Rivers WaterPark