
Holiday houses in Santa Panagia
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness and more.

Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Sea-View Loft. Elegant & Bright Old Town Retreat
Experience the timeless charm of Ortigia from this elegant 80 m² sea-view apartment. Perfect for couples, families, or small groups, Suite 18 blends authentic Sicilian character with modern comfort, just steps from the island’s iconic landmarks. Wake up to breathtaking harbour views from your private balcony, relax in the bright open-plan living area, and enjoy a fully equipped kitchen, a peaceful bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, heating and lift access.

Light and Relaxation: Large Open-Plan Space Overlooking the Garden
Located in a private wing of the villa with its own entrance, this 95-square-metre open-plan space combines sophistication and modernity. The large windows flood the rooms with natural light, while the furnishings naturally define the different areas. A perfect balance of design, comfort and nature: the spaces blend harmoniously with the garden, creating a sense of relaxation and privacy. For reasons of safety and comfort, the facility only accommodates children aged 10 years and over.

Casa Carlotta - Stunning uninterrupted sea views
In 2022 Casa Carlotta has undergone a full and radical renovation to enhance the beauty of the position of the house and to increase the comfort for our guests. We are happy to share the results with our guests. In 2024 we have further upgraded the kitchen area. Casa Carlotta offers a stunning location; an uninterrupted 180-degree sea view of the mediterranean, enjoyed from the large terrace that surrounds the house, and access to the sea which is just a few short steps away.

Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Sky Rooftop Ortigia
In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.

Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Cortile Crocefisso apartment
Our flats are located in the Jewish quarter of Ortigia,a few steps from Piazza Duomo and the sea. The apartment is equipped with every comfort, a complete kitchen, AC, SmartTV, WiFi, washer-dryer, safe. It consists of one living room with a sofa bed, a kitchen with a a laundry corner, 2 double bedrooms with their respective 2 private bathrooms and can accommodate groups/families of 4/6 pax.

Casa Francesca
Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Lovely apartment in the heart of Ortigia
In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.

[Elegant] DreamSuite - 300m from Ortigia
-Quality furnishings, comfortable bed and sofa bed - Parking spaces in the area -300m from the historic center - Surrounding area full of bars and restaurants - The house consists of a living area, equipped kitchen and a bedroom - 2 bathrooms with shower - 2 smart TVs - Free Wi-Fi - Fully air-conditioned and soundproofed environment
Popular amenities for Santa Panagia holiday rentals
Other great holiday rentals in Santa Panagia

Spacious flat close to the sea! + Patio & parking

Allisola Country Villa - casa Carrubo

Aglaia apartment Ortigia Island terrace

Vigliena Fine apartments 1

Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach

Casa Sirokos

150sqm 2BA Prime Location Car Access Dining Guide

Timeless: Detached villa with infinity pool
Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Fondachello Village
- Piano Provenzana
- Teatro Massimo Bellini
- Etnaland
- Villa Bellini
- Castello Maniace
- Greek Theatre of Syracuse
- Castello di Donnafugata
- Nature reserve of Vendicari
- Oasi Del Gelsomineto
- Spiaggia Vendicari
- Sampieri Beach
- Fishmarket
- Isola delle Correnti
- Aci Trezza
- Museo Emilio Greco
- Necropolis of Pantalica
- Temple of Apollo
- Noto Antica
- Monastery of San Nicolò l'Arena





