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Holiday houses in Santa Panagia

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Top-rated holiday rentals in Santa Panagia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Syracuse
4.97 out of 5 average rating, 58 reviews

150sqm 2BA Prime Location Car Access Dining Guide

💎 Live the Sicilian Dolce Vita Newly renovated and thoughtfully designed, it blends historic elegance with modern comfort - placing you right at the heart of Ortigia’s timeless charm Why You’ll Love It 📍 Unbeatable Location – Steps from Piazza Duomo, local market 🚗 Rare Car Access – Easy luggage drop-off directly by the apartment 🏡 Elegant & Spacious – High ceilings, generous rooms 🌅 Stunning Views – 3 balconies overlooking Piazza Archimede 💡 Insider Tips – through our digital GuestGuide

Top Guest favourite
Home in Noto
4.96 out of 5 average rating, 54 reviews

Penthouse Lady Packard

Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Top Guest favourite
Condo in Syracuse
4.99 out of 5 average rating, 359 reviews

Sea-View Loft. Elegant & Bright Old Town Retreat

Experience the timeless charm of Ortigia from this elegant 80 m² sea-view apartment. Perfect for couples, families, or small groups, Suite 18 blends authentic Sicilian character with modern comfort, just steps from the island’s iconic landmarks. Wake up to breathtaking harbour views from your private balcony, relax in the bright open-plan living area, and enjoy a fully equipped kitchen, a peaceful bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, heating and lift access.

Guest favourite
A modern kitchen features a large dining table set with colorful plates. A prominent clock on the wall enhances the space, while yellow cabinets and grey countertops provide a contemporary touch. Ample natural light enters through the window, illuminating the room.
Apartment in Syracuse
4.96 out of 5 average rating, 206 reviews

Brand new apartment with patio across Ortigia

Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!

Superhost
A spacious sleeping area features a large bed with soft green accents and warm wooden flooring. A comfortable chair is positioned beside the bed, and a round rug with leaf patterns adds a touch of nature. Natural light filters in through large windows covered with shades.
Condo in Syracuse
4.83 out of 5 average rating, 6 reviews

Light and Relaxation: Large Open-Plan Space Overlooking the Garden

Located in a private wing of the villa with its own entrance, this 95-square-metre open-plan space combines sophistication and modernity. The large windows flood the rooms with natural light, while the furnishings naturally define the different areas. A perfect balance of design, comfort and nature: the spaces blend harmoniously with the garden, creating a sense of relaxation and privacy. For reasons of safety and comfort, the facility only accommodates children aged 10 years and over.

Top Guest favourite
Home in Syracuse
4.97 out of 5 average rating, 37 reviews

Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach

On a quiet road a few steps away from the sea and Cala Rossa beach, this luminous independent 3 beds and 3 bathrooms townhouse, has been designed to make your holiday in Ortigia unforgettable. "CASA SANTINI" is the product of our family's love for Ortigia and the vision of our local Architect Ignazio. The house has been fully renovated with meticulous attention to details, keeping the old features and adding all comforts and modern elements to create an elegant and calming space.

Top Guest favourite
A serene pool area is surrounded by lush greenery, featuring a crystal-clear swimming pool. Comfortable loungers and a white umbrella are positioned nearby. A decorative stone bench displays two patterned pillows, adding a subtle touch to the inviting outdoor space.
Holiday home in Syracuse
4.94 out of 5 average rating, 48 reviews

Casa Sirokos

Casa Sirokos is a detached villa facing the pool, surrounded by the greenery of the most panoramic residential area of Syracuse. It features local architecture that blends with large outdoor spaces and typical Sicilian countryside gardens. The cottage is one of two independent accommodation units that are part of this property, which also offers an apartment located on the first floor of an old manor house. Our sophisticated and relaxing atmosphere sets us apart!

Superhost
A modern living area is presented, featuring a flat-screen television mounted on a light-colored wall unit. A dining table with four black chairs is positioned nearby, and a dark area rug is laid on the tiled floor. Soft lighting is provided by exposed bulbs.
Apartment in Syracuse
4.69 out of 5 average rating, 39 reviews

Casa Salgiò

Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Top Guest favourite
Apartment in Syracuse
5 out of 5 average rating, 41 reviews

Casa Sbarcadero

Casa Sbarcadero is just a 6-minute walk from the historic center of the island of Ortigia and about 20 minutes from the Neapolis archaeological area. The apartment offers access to the public solarium below, perfect for relaxing. The apartment consists of three bright rooms overlooking the small port, two bathrooms, a spacious living room and a well-equipped kitchen. The bus and train station is a 15-minute walk away.

Guest favourite
A softly lit hallway features a framed floral painting above a white console table. A green glass lamp and a small potted plant are placed on the table, while another plant sits nearby on the floor, contributing to a calming atmosphere.
Condo in Syracuse
4.97 out of 5 average rating, 64 reviews

Comfortable apartment with reserved parking space

Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Top Guest favourite
Home in Plemmirio
4.98 out of 5 average rating, 114 reviews

Casa Francesca

Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Guest favourite
The spacious terrace is furnished with a wooden seating area, featuring a lounge chair and a table. Potted plants are placed around the area, and a light canopy provides shade. A peaceful view of the rooftops is visible against a soft evening sky.
Condo in Syracuse
4.91 out of 5 average rating, 101 reviews

Lovely apartment in the heart of Ortigia

In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.

Popular amenities for Santa Panagia holiday rentals