
Holiday houses in Santa Panagia
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Top-rated holiday rentals in Santa Panagia
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150sqm 2BA Prime Location Car Access Dining Guide
💎 Live the Sicilian Dolce Vita Newly renovated and thoughtfully designed, it blends historic elegance with modern comfort - placing you right at the heart of Ortigia’s timeless charm Why You’ll Love It 📍 Unbeatable Location – Steps from Piazza Duomo, local market 🚗 Rare Car Access – Easy luggage drop-off directly by the apartment 🏡 Elegant & Spacious – High ceilings, generous rooms 🌅 Stunning Views – 3 balconies overlooking Piazza Archimede 💡 Insider Tips – through our digital GuestGuide
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Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.
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Brand new apartment with patio across Ortigia
Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!
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Light and Relaxation: Large Open-Plan Space Overlooking the Garden
Located in a private wing of the villa with its own entrance, this 95-square-metre open-plan space combines sophistication and modernity. The large windows flood the rooms with natural light, while the furnishings naturally define the different areas. A perfect balance of design, comfort and nature: the spaces blend harmoniously with the garden, creating a sense of relaxation and privacy. For reasons of safety and comfort, the facility only accommodates children aged 10 years and over.
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Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach
On a quiet road a few steps away from the sea and Cala Rossa beach, this luminous independent 3 beds and 3 bathrooms townhouse, has been designed to make your holiday in Ortigia unforgettable. "CASA SANTINI" is the product of our family's love for Ortigia and the vision of our local Architect Ignazio. The house has been fully renovated with meticulous attention to details, keeping the old features and adding all comforts and modern elements to create an elegant and calming space.
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Casa Sirokos
Casa Sirokos is a detached villa facing the pool, surrounded by the greenery of the most panoramic residential area of Syracuse. It features local architecture that blends with large outdoor spaces and typical Sicilian countryside gardens. The cottage is one of two independent accommodation units that are part of this property, which also offers an apartment located on the first floor of an old manor house. Our sophisticated and relaxing atmosphere sets us apart!
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Aglaia apartment Ortigia Island terrace
Nel centro autentico dell'isola d'Ortigia, nell'antico quartiere dei pescatori della Graziella, a due passi dallo storico mercato , l'appartamento è in una zona interamente pedonale dove il tempo sembra non essere passato. La tranquillità delle stradine che si intersecano è tipica di questo quartiere dell'isola di Ortigia. A pochi metri si raggiunge il duomo e le principali meraviglie della città. Poco distante l'unico parcheggio dell'isola pedonale.
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Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.
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Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.
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Sky Rooftop Ortigia
In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.
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Ortigia Prestige Apartment with a view
Elegant, recently renovated apartment with sea view, bright rooms, high ceilings and stone details. It has a living room with TV, equipped kitchen, double bedroom, modern bathrooms with walk-in shower, WiFi and air conditioning. Ideal location on the waterfront, walking distance to restaurants, shops and attractions. Perfect for couples, families or travelers looking for comfort, relaxation and charm.
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Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
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Popular amenities for Santa Panagia holiday rentals
Other great holiday rentals in Santa Panagia

Ancient Greece House - Greek Theater
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Casa Sbarcadero
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Big apartment, Access to the beach(rocky)
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Riccio di Mare - Large and bright flat on the sea
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Private Heated Pool•Sea View•Walk to Beach•Shati
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Allisola Country Villa - Ulivo house
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Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Castello Ursino
- Fondachello Village
- Piano Provenzana
- Teatro Massimo Bellini
- Etnaland
- Villa Bellini
- Castello Maniace
- Greek Theatre of Syracuse
- Castello di Donnafugata
- Nature reserve of Vendicari
- Oasi Del Gelsomineto
- Spiaggia Vendicari
- Sampieri Beach
- Fishmarket
- Isola delle Correnti
- Aci Trezza
- Museo Emilio Greco
- Necropolis of Pantalica
- Temple of Apollo
- Noto Antica
- Noto Cathedral





