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House holiday rentals in Santa Isabel

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Isabel

Guests agree: These houses are highly rated for location, cleanliness and more.

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Guest favourite
A modern single-story home is presented with a minimalist design. The exterior features columns in a vibrant red and a pathway lined with stone tiles leading to the entrance. Landscaping includes neatly arranged plants in decorative pots, enhancing the inviting surface.
Home
4.81 out of 5 average rating, 147 reviews

Rancho Luna Suite Jacuzzi. Near beach & hot spring

Kick back and relax in this modern and stylish space with jacuzzi, near thermal hot springs, rivers and best beaches. Hacienda Doña Elba, Coamo hot springs, Aventura 4x4, Caribbean Cinemas, Velódromo de Coamo, Maratón San Blas, Salinas, Juana Diaz, Rest El Platanar, La Parrila 153, Isabelle Rest, Bar O Bar, Ruta 153 Gastro Bar, Rest La Guitarra, Rest La Ceiba, Carnaval Rest., Playa Jauca, Malecón de Santa Isabel, Sunset Bar and Grill, Sea Angels Rest, Cabas Rest, El Rincon del Pescador and more.

Superhost
Home in Las Ollas
4.81 out of 5 average rating, 26 reviews

The Local's Getaway : Dip Pool, King Bed, AC

Welcome to your Puerto Rican retreat in Santa Isabel! Our cozy 3-bedroom home is perfect for families, featuring quality AC, a dipping pool, a fully equipped kitchen, & plenty of space to relax. Gather in the living room with TV and board games, or step outside to enjoy the private back patio, grill, and fresh tropical air. Minutes from local restaurants, beautiful beaches, horse farms, and hidden gems, our home is the ideal base for sunshine, culture, and unforgettable family memories.

Home
4.58 out of 5 average rating, 26 reviews

Santa Isabel Ocean Paradise Retreat

Beachfront Living | Ocean Views | Wind, Kayak & Watersports Paradise 🌴 Welcome to paradise in Santa Isabel! 🌊 Discover your ideal escape just steps from the beach in this cosy and modern accommodation with ocean views. Perfect for sports, adventure and outdoor lovers, this space connects you with the best that Puerto Rico has to offer. 🏖️ Unique location: Walk straight from your door to the soft sandy beach, enjoy the sound of the waves and watch

Guest favourite
Home in Santa Isabel
4.93 out of 5 average rating, 14 reviews

Lolo's House | Private Pool & Relaxation | BBQ

Discover your home away from home in 𝓛𝓸𝓵𝓸'𝓼 𝓗𝓸𝓾𝓼𝓮. Imagine waking up with stunning views of the windmills, enjoying the tranquility, and exploring everything the area has to offer. Enjoy the pool & terrace in total privacy. A surprising distance from Prados Mall, Movie Theater, Starbucks, Fast Food. 2 minutes from Highway #52 and 3 minutes from Walmart. The Coamo Hot Springs are the only hot sulfur waters in PR just 15 minutes away

Superhost
Home in Playa
New place to stay

Couples Oceanfront Retreat | Hot Tub

Escape to Casa Brisa, an oceanfront beach house thoughtfully designed with couples in mind. Enjoy direct beach access, breathtaking ocean views, a private hot tub, and a spacious outdoor living area. Whether you’re celebrating a special occasion or simply looking to unwind, Casa Brisa is the perfect place to relax to the sound of the waves and experience Puerto Rico’s beautiful southern coast.

Guest favourite
Home in Santa Isabel
5.0 out of 5 average rating, 5 reviews

Casa Palma Serena - Garden Retreat • Tropical Stay

Bright and spacious 2-bedroom home in a gated community in Santa Isabel, Puerto Rico. Perfect for families or couples, it features a King bedroom, a Queen bedroom, 2 full bathrooms, a fully equipped kitchen, in-unit laundry, and stylish indoor and outdoor living areas. Guests enjoy access to shared pool and playgrounds, all just a short drive from beaches, nature, and local attractions.

Guest favourite
A shaded outdoor seating area is furnished with a dining table and chairs, accompanied by a cozy lounge set. The space overlooks a lush green lawn and features a pool with a modern design. Play structures are visible in the background, enhancing the family-friendly environment.
Home in Jauca
4.81 out of 5 average rating, 72 reviews

Salinas Blue House 2 In the Beach, Private Pool

Create unforgettable memories in this unique family-friendly accommodation. With a view and access to the beach within a minute's walk. Swimming pool with modern jets, mini golf, playground, billiards, terrace, gazebo. 4 bedrooms, 4 double bathrooms, outdoor games, BBQ and more. We've definitely thought of all the family members, everyone will have their space and fun regardless of age.

Guest favourite
An indoor terrace is visible, featuring a cozy seating area with a blue sofa, and two red chairs positioned around a rectangular pool. Sliding glass doors open to the outdoor space adorned with tropical plants and a colorful wall, creating a bright and inviting atmosphere.
Home in Santa Isabel
4.91 out of 5 average rating, 76 reviews

Duques@ House

Centrally house in the heart of Santa Isabel, Puerto Rico. Just a couple minutes away from amazing restaurants, movie theater, Bars and so much more. Perfect for a weekend getaway, business trip, family activity or cozy home base while exploring everything Puerto Rico South has to offer. Outsite, enjoy the expansive private yard, Bar with TV, mini kitchen and pool.

Guest favourite
The exterior of a modern home is visible, featuring a combination of light and dark gray walls. Large windows with white shutters allow natural light to enter. A concrete driveway leads to a garage with a glass door, set beneath a partly cloudy blue sky.
Home in El Ojo
4.8 out of 5 average rating, 41 reviews

Hidden House

Centrally located, minutes from Walmart, the Mall, Santa Isabel esplanade and minutes from Coamo's baths. Comfortable and pleasant house. Peaceful, quiet and cozy area. Excellent space to rest and spend the night after a day of work or a day of walking in the area.

Superhost
A vibrant teal exterior of a home is featured, showcasing a welcoming atmosphere. Two white chairs are positioned on the front porch. The signage reading 'Santa Isabel' is visible in the background, complemented by a sunny sky. A well-equipped kitchen area is detailed with a modern stove and countertops.
Home in Santa Isabel
4.84 out of 5 average rating, 148 reviews

Casa Del Sol-Modern Home in Puerto Rican Paradise

Cozy and modern 2-bedroom, 1-bathroom home on the southern part of the island. The home offers accommodations for 5 people, making it ideal for families or couples. Very close to many beaches and other sites you may find on the island.

Top Guest favourite
Two comfortable lounge chairs are positioned on a wooden deck facing the ocean. A small table sits between the chairs, offering a place for drinks. Lush greenery lines the deck, complementing the serene seascape under a clear blue sky.
Home in Santa Isabel PR
5.0 out of 5 average rating, 56 reviews

Las Casitas Beach Retreat (Cabin #2)

An exclusive and private family space on the coast of Santa Isabel PR. Experience the unique experience offered by our space, with amazing sunsets and the relaxing sound of the waves of the Caribbean Sea.

Superhost
Home in Playita Cortada
5.0 out of 5 average rating, 7 reviews

Oceanfront paradise I infinity pool I firepit

Oceanfront 3BR/2BA villa with infinity pool, beautiful garden, terrace, and stunning views — perfect for families or couples.

Popular amenities for Santa Isabel house rentals