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Holiday houses in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Loft in Iztapalapa
5 out of 5 average rating, 29 reviews

Private Microsuite Const 1917 Iztapalapa

Hermosa y moderna Microsuite privada en el oriente de CDMX, ideal para parejas, viaje de trabajo, visita familiar o descanso. Cuenta con cama matrimonial, baño completo, wifi, escritorio, TV, closet y cocineta con fregadero. Cerca de Constitución de 1917, con conexión a Metro, Trolebús Elevado y Cablebús. Si vienes por trabajo, puedes solicitar coworking o sala profesional en Punto de Negocios, frente al alojamiento, sujeto a disponibilidad por Airbnb. Tu base privada para moverte mejor.

Guest favourite
Guest suite in Roma Norte
4.91 out of 5 average rating, 11 reviews

JADE (one)

Un refugio inspirado en la filosofía wabi-sabi, donde la belleza se encuentra en la imperfección y en el paso del tiempo. En esta casa de los años 40, los materiales originales fueron preservados y resaltados, dejando ver sus texturas, grietas y huellas naturales que honran su historia. El mobiliario se compone de piezas únicas de una colección privada, que aportan carácter, autenticidad y una atmósfera íntima. Un espacio cálido, ideal para descansar, contemplar y habitar la calma.

Guest favourite
A spacious living area is depicted, featuring a round glass dining table surrounded by six woven chairs. A wooden bookshelf filled with books is visible in the background, along with a comfortable seating area containing a dark sofa. A large television is mounted on the wall.
Loft in Xochimilco
4.91 out of 5 average rating, 89 reviews

Beautiful suite with a separate entrance

Relax on this unique and quiet getaway in this beautiful space surrounded by nature. Beautiful garden and architecture. Close to attractions in Xochimilco such as the trajineras and the canals and chinampas of Xochimilco and Cuemanco. Traditional village south of the city. Relax in our beautiful place, surrounded by nature. Beautiful green garden and architecture. Close to main attractions like Trajineras, Xochimilco town, canals and chinampas. Traditional town south of the city

Top Guest favourite
Apartment in Roma Norte
5 out of 5 average rating, 9 reviews

Designer's Haven in Roma with Private Rooftop

Experience Mexico City like a local from this beautifully designed three-story home in the heart of Roma Norte. Walk to the city's best restaurants, cafés, boutiques, galleries, and parks. Accommodates up to 6 guests with 3 bedrooms, 3 full bathrooms, a spectacular private rooftop terrace, 4 Smart TVs, private elevator access, parking, and 24/7 security. A rare combination of space, privacy, design, and location in one of the city's most desirable neighborhoods.

Superhost
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Coyoacán
4.88 out of 5 average rating, 226 reviews

Casa Mavi's loft in Coyoacán

Welcome to Coyoacán! Great 120 m2 loft located just a 5-minute walk from downtown Coyoacán. Experience this quiet and bright open space, ideal for resting or working and decorated with objects full of stories. The loft is located on the third floor of Casa Mavi, an old factory that was remodeled to create a place full of charm that makes it unique. It has shared terraces. With option for a third guest. 200 megabyte Wi-Fi.

Guest favourite
A cozy bedroom features a spacious bed with a soft grey headboard and decorative cushions. A sleek bedside lamp provides gentle illumination, while modern wooden cabinetry adds warmth to the space. A grey armchair is positioned nearby, complemented by delicate white flowers in the foreground.
Loft in Tlalpan
4.88 out of 5 average rating, 932 reviews

Punto Lofts Periférico Sur (South Peripheral Point Lofts)

Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.

Top Guest favourite
Loft in Ayapango de Gabriel Ramos M.
5 out of 5 average rating, 19 reviews

Beautiful apartment with garden and volcano view

Escape to a dreamy retreat on the volcano route. Perfect for romantic getaways or family gatherings. Enjoy Stunning views of the volcanoes from your private garden, barbecue area and stone oven bring out the chef in you. Spacious and cozy space to relax and enjoy. Located in a picturesque village near Iztapopo National Park, this oasis is the ideal place to disconnect and reconnect with nature and your loved ones.

Superhost
A tranquil pond surrounded by trees features three ducks leisurely swimming. The water reflects the greenery, creating a calm and natural setting. The landscape includes dry earth and grasses, indicative of the outdoor environment.
Cottage in Tlalpan
4.92 out of 5 average rating, 52 reviews

La Ciruelita - Country house with fireplace

Relax with the whole family in this accommodation where tranquility is breathed. You can cook in the pizza oven, play tennis, go to the tree house, or rest by walking among the cherry trees in the 6000 square meters of completely fenced land. At night you can make a campfire and see the stars from the inside through the skylights. A cozy atmosphere in the woods that will revitalize you.

Guest favourite
Cabin in Tlalmanalco de Velázquez
5 out of 5 average rating, 12 reviews

A little house near the volcanoes.

Village house near the volcanoes Enjoy a unique getaway in our cozy little house, ideal for 2 to 4 people. Perfect for families who want to spend a quiet and cozy weekend. Includes: Bed (King Size) + sofa bed (King Size) Kitchenette Mini fridge Microwave oven TV Wi-Fi Kitchen accessories Experience the local experience with comfort and charm, very close to the volcanoes.

Guest favourite
A modern living area features a combination of comfortable grey sofas and a dining table. Soft blue and beige tones enhance the space, with decorative wall art complementing the minimalist design. Large windows with horizontal blinds allow natural light to illuminate the room.
Home in Xochimilco
5 out of 5 average rating, 12 reviews

SmartHome & Rooftop in Xochimilco-Enjoy Live Relax

Stay in a fully equipped luxury apartment designed for comfort and convenience. Unwind on your private rooftop terrace and enjoy a Smart Home experience. Your stay includes a fully equipped kitchen, washer, high-speed WiFi, and free parking. Ideally located near Xochimilco’s Historic Center, with easy access to public transportation, restaurants, cafés, and the city’s main roads.

Top Guest favourite
A charming outdoor patio is surrounded by vibrant greenery and a blue-walled house. A round glass table is complemented by six white metal chairs, creating an inviting space for dining or gathering. Potted plants and flowers add color to the serene environment.
Home in Coyoacán
4.97 out of 5 average rating, 109 reviews

Casa Omac | Colonial house with two patios

Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.

Top Guest favourite
The exterior of a two-story house is surrounded by lush greenery and vibrant planters. A small terrace features a white umbrella, where a person is seated, enjoying the garden view. A paved pathway leads to the entrance, enhancing the welcoming atmosphere.
Loft in Del Carmen
4.95 out of 5 average rating, 256 reviews

Loft Coyoacan Viveros (Bow)

A super special and very cozy place in the heart of Coyoacán! right next to Coyoacán nurseries, on Melchor Ocampo street Ideal for a couple with or without children who want to enjoy a pleasant stay or a good walk through the wonders of Coyoacán :)

Popular amenities for Santa Cruz holiday rentals