
Holiday houses in Santa Cruz
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness and more.

Kaya Kalpa-Organic Designer Apartment in Condesa
After a year-long remodeling project, I’m thrilled to present this personal residence Kaya Kalpa. Every inch of the property has been thoughtfully remodeled. Ideal place for artists, wanderers, all walks of life practitioners to come reset, reflect, and create. The space is located on Amsterdam street in Condesa, one block from Parque Mexico. You’ll find all nice restaurants, cafes, and stores downstairs. Big supermarket, local Mercado, metro station…all within 5 minutes walking distance.

Cabin with garden and kitchen near chinampas
Escape to a 1,080 ft² cabin retreat nestled in Xochimilco’s UNESCO-protected chinampa zone. Bask in serenity with a 4,310 ft² private garden, inside free parking, and optional lake access. Inside, free parking, plush linens, a fan, complimentary tea, high-speed Wi-Fi, etc., await you—while modern security cameras ensure peace of mind. Stroll one minute to the Olympic track or lagoon, and 20 minutes to Xochimilco Centro. Unplug under a canopy of stars in this elegant, eco-friendly sanctuary.

Private Microsuite Const 1917 Iztapalapa
Hermosa y moderna Microsuite privada en el oriente de CDMX, ideal para parejas, viaje de trabajo, visita familiar o descanso. Cuenta con cama matrimonial, baño completo, wifi, escritorio, TV, closet y cocineta con fregadero. Cerca de Constitución de 1917, con conexión a Metro, Trolebús Elevado y Cablebús. Si vienes por trabajo, puedes solicitar coworking o sala profesional en Punto de Negocios, frente al alojamiento, sujeto a disponibilidad por Airbnb. Tu base privada para moverte mejor.

José Clemente Orozco House Coyoacán
Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.

JADE (one)
Un refugio inspirado en la filosofía wabi-sabi, donde la belleza se encuentra en la imperfección y en el paso del tiempo. En esta casa de los años 40, los materiales originales fueron preservados y resaltados, dejando ver sus texturas, grietas y huellas naturales que honran su historia. El mobiliario se compone de piezas únicas de una colección privada, que aportan carácter, autenticidad y una atmósfera íntima. Un espacio cálido, ideal para descansar, contemplar y habitar la calma.

Beautiful suite with a separate entrance
Relax on this unique and quiet getaway in this beautiful space surrounded by nature. Beautiful garden and architecture. Close to attractions in Xochimilco such as the trajineras and the canals and chinampas of Xochimilco and Cuemanco. Traditional village south of the city. Relax in our beautiful place, surrounded by nature. Beautiful green garden and architecture. Close to main attractions like Trajineras, Xochimilco town, canals and chinampas. Traditional town south of the city

My San Angel Refuge
Mi Refugio San Angel, is a spacious and modern space, to feel out of the city, being centrally in it. It has a Temazcal (under reservation), hydromassage tub, terraces, garden with hammocks, lounge chair, outdoor dining area, bonfire area, indoor fireplace. 2 rooms with full bathroom, queen size sofa bed; open, spacious and fully equipped kitchen. Private parking. The main room can be opened to a view towards the double height of its large room.

Punto Lofts Periférico Sur (South Peripheral Point Lofts)
Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.

Beautiful apartment with garden and volcano view
Escape to a dreamy retreat on the volcano route. Perfect for romantic getaways or family gatherings. Enjoy Stunning views of the volcanoes from your private garden, barbecue area and stone oven bring out the chef in you. Spacious and cozy space to relax and enjoy. Located in a picturesque village near Iztapopo National Park, this oasis is the ideal place to disconnect and reconnect with nature and your loved ones.

A little house near the volcanoes.
Village house near the volcanoes Enjoy a unique getaway in our cozy little house, ideal for 2 to 4 people. Perfect for families who want to spend a quiet and cozy weekend. Includes: Bed (King Size) + sofa bed (King Size) Kitchenette Mini fridge Microwave oven TV Wi-Fi Kitchen accessories Experience the local experience with comfort and charm, very close to the volcanoes.

Rooftop & SmartHome in Xochimilco-Enjoy Live Relax
Stay in a fully equipped luxury apartment designed for comfort and convenience. Unwind on your private rooftop terrace and enjoy a Smart Home experience. Your stay includes a fully equipped kitchen, washer, high-speed WiFi, and free parking. Ideally located near Xochimilco’s Historic Center, with easy access to public transportation, restaurants, cafés, and the city’s main roads.

Casa Omac | Colonial house with two patios
Typical colonial house, located in the most picturesque and emblematic street of Coyoacán. The style is reminiscent of Frida Kahlo's Blue House, which is a few minutes' walk away. Organized around a large internal patio, the house has 5 double rooms and can host up to 10 people, making it ideal for groups and families.
Popular amenities for Santa Cruz holiday rentals
Other great holiday rentals in Santa Cruz

Cozy cabin with fireplace, Quinta Josefina

Come & Dream in Quetzalcoatl`s Nest

Zen Apartment in Roma with A/C

Rest house - Xochimilco kayak tours

Move into a new house, comfortable and quiet.

Designer Stay in Condesa

Pedregal Garden House

Magical For 6 Rome, balcony, washing machine, desk
Destinations to explore
- The Angel of Independence
- Foro Sol
- Val'Quirico
- Aztec Stadium
- Palacio de los Deportes
- Autódromo Hermanos Rodríguez
- World Trade Center Mexico City
- Basilica of Our Lady of Guadalupe
- Six Flags Mexico
- Monument To the Revolution
- Pyramids Of Teotihuacán
- Las Estacas Parque Natural
- Pepsi Center Wtc
- Alameda Central
- Embajada De Los Estados Unidos De América
- Palacio de Bellas Artes
- Jardines de México
- Izta-Popo Zoquiapan National Park
- Los Dinamos
- El Rollo Parque Acuático
- Constitution Square
- Citibanamex Center
- Frida Kahlo Museum
- Bosque Geométrico





