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Holiday houses in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Townhouse in Chalco

Family Home in a Private, Quiet, and Safe Area.

Your home away from home in the State of Mexico! 🏡✨ Enjoy a peaceful, comfortable, and safe stay in this spacious house that accommodates 5 people. It features: 🛏️ 3 bedrooms, each with a double bed. 🛋️ 2 hallways, each with a sofa bed. 🚽 2.5 bathrooms (2 full bathrooms and one half-bath). 🍳 Fully equipped kitchen, Smart TV, and Wi-Fi. 🚗 Private, secure parking. Pets welcome (please check the rules regarding the 500 MXN surcharge). Total privacy for your trip! Pura vida! 🇨🇷🇲🇽

4.98 out of 5 average rating, 63 reviews
Top Guest favourite
Home in Del Carmen

José Clemente Orozco House Coyoacán

Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.

4.95 out of 5 average rating, 393 reviews
Top Guest favourite
A welcoming living space features a blend of textures and decor. A wooden dining table is set near a potted plant, while a comfortable seating area is visible underneath an archway, adorned with decorative masks and strings of beads.
Loft in Villa Coyoacán

Artisanal Loft in Coyoacán

Located in the heart of Mexico City’s oldest neighborhood, 5 centuries of stunning architecture, cobblestone streets, cafes, parks and markets full of artisanal treasures are right outside your door. Jardin Centario Park is 2 blocks away where you can catch the citywide Turibus and the local tourist trolley. The Frida Kahlo museum and famous Mercado 89 is a lovely 10 minute walk through this gem of CDMX that UNESCO declared a Cultural Heritage of Humanity.

4.96 out of 5 average rating, 50 reviews
Top Guest favourite
The building presents a modern design with a prominent use of green glass. The façade is enhanced by colorful window coverings, flanked by two parked cars. A clear sky serves as a backdrop, highlighting the structure's height and the surrounding area.
Apartment in Ciudad Nezahualcóyotl

Safety and Comfort in Edo.MEX

An apartment with great comfort, space, and security. It has a closed circuit, automatic main entrance door, alarm against theft, carbon monoxide and fire, excellent internet quality, and Smart TV. It has a lighting system with 3 shades: White, semi-warm and warm light, suitable for study and rest. The central stairs have handrails, non-slip, and sensor lighting. Fully-equipped kitchen and bathroom. Practical location with amenities available.

4.98 out of 5 average rating, 256 reviews
Superhost
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Coyoacán

Casa Mavi's loft in Coyoacán

Welcome to Coyoacán! Great 120 m2 loft located just a 5-minute walk from downtown Coyoacán. Experience this quiet and bright open space, ideal for resting or working and decorated with objects full of stories. The loft is located on the third floor of Casa Mavi, an old factory that was remodeled to create a place full of charm that makes it unique. It has shared terraces. With option for a third guest. 200 megabyte Wi-Fi.

4.87 out of 5 average rating, 232 reviews
Top Guest favourite
Loft in Ayapango

Beautiful apartment with garden and volcano view

Escape to a dreamy retreat on the volcano route. Perfect for romantic getaways or family gatherings. Enjoy Stunning views of the volcanoes from your private garden, barbecue area and stone oven bring out the chef in you. Spacious and cozy space to relax and enjoy. Located in a picturesque village near Iztapopo National Park, this oasis is the ideal place to disconnect and reconnect with nature and your loved ones.

5.0 out of 5 average rating, 22 reviews
Guest favourite
Cabin in Tlalmanalco de Velázquez

A little house near the volcanoes.

Village house near the volcanoes Enjoy a unique getaway in our cozy little house, ideal for 2 to 4 people. Perfect for families who want to spend a quiet and cozy weekend. Includes: Bed (King Size) + sofa bed (King Size) Kitchenette Mini fridge Microwave oven TV Wi-Fi Kitchen accessories Experience the local experience with comfort and charm, very close to the volcanoes.

5.0 out of 5 average rating, 14 reviews
Top Guest favourite
Guest suite in Coyoacán

Casita Suite | WiFi, bath, kitchen | in Coyoacan

Welcome to La Casita, a 450 sq (42 m²) suite that is part of the seven suites in the iconic El Guajolote de Coyoacan. 📍 Just steps away from the Frida Kahlo House and Coyoacán Plaza. 🔐 Private spaces: kitchen, private bathroom, and a cozy sitting area. 🛏️ Queen Size bed. ✍️ Ideal for couples, writers, or nomads. 🌿 Enjoy the tranquility and authenticity of the neighborhood.

4.88 out of 5 average rating, 444 reviews
Guest favourite
Apartment in Centro

Luxury Loft Historic Center - Next to Bellas Artes

New loft in a modern building facing Alameda Central, ideal for two people. It has a 50" TV, elevator, kitchen equipped with microwave, private bathroom and Wi-Fi. Just 10 minutes from the Historic Center and close to iconic places such as Bellas Artes, Torre Latinoamericana and museums. Perfect for a comfortable, central and stylish stay in Mexico City.

4.84 out of 5 average rating, 263 reviews
Guest favourite
Apartment in Condesa

Parkside Residence w/Balcony in Condesa

This suite offers an elegant three-bedroom residence in the heart of Condesa. Enjoy expansive living spaces, private balconies overlooking tree-lined streets, a fully equipped kitchen, and boutique hospitality with daily housekeeping, rooftop access, fitness center, and personalized service.

4.92 out of 5 average rating, 617 reviews
Top Guest favourite
Guesthouse in Xochimilco

Garden and beautiful house for events and stays

Camino Real Event Garden Disconnect from your concerns in this spacious and serene space. Ideal for all kinds of events, children's parties, meetings, weddings, corporate events, workshops, yoga courses or any other outdoor exercise or activity 🍃🌿🌤️

5.0 out of 5 average rating, 52 reviews
Top Guest favourite
An open living space features a dining area with a round table surrounded by chairs, overlooking a cozy lounging area with a spacious bed. Plants are placed throughout, with large windows allowing natural light to illuminate the room. Wooden beams add a rustic touch to the modern design.
Apartment in Roma Norte

A little house

Una Casita is located on a quiet street in the heart of Condesa. It is surrounded by delicious restaurants, fantastic coffee, and leafy walks. Hosted by a Bosnio-Mexican couple that is madly in love with this beautiful city.

5.0 out of 5 average rating, 82 reviews

Popular amenities for Santa Cruz holiday rentals