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Holiday houses in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 6 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Diseñado para huéspedes de gustos exigentes que buscan una experiencia superior a un hotel 5 estrellas. Ubicado en Equipetrol, la zona más exclusiva y segura de Santa Cruz, este elegante Dpto. en penúltimo piso ofrece doble balcón con vistas únicas! Premium amenities como sky pool, lounge, billar, churrasqueras, gym completo y más! Rodeado de los mejores restaurantes, bares, cafés, teatros, tiendas y centros empresariales. Ideal para viajes ejecutivos, escapadas de lujo o estadías inolvidables.

Superhost
A modern outdoor pathway is flanked by sleek buildings and lush greenery. Soft, natural light filters through the space, illuminating the smooth stone finish of the walkway. Curved steps lead up to elevated garden areas, creating a harmonious blend of nature and architecture.
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 72 reviews

Luxury 18th-Floor Apt | City View, Pools & Netflix

Enjoy a comfortable and stylish stay in this modern 18th-floor apartment with panoramic city views in Santa Cruz. Ideal for families, business travelers, and groups, the apartment offers space, privacy, fast Wi-Fi, and resort-style amenities, all within a secure high-rise building. For security purposes, there is a Ring doorbell camera located outside the apartment entrance, facing the exterior hallway. There are no cameras inside the apartment. there is security on duty 24x7 4th bed inflatable

Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Apartment in Santa Cruz de la Sierra
4.91 out of 5 average rating, 156 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 19 reviews

POX | Green Tower 17th Floor, Luxury in Equipetrol

✨ Vive la experiencia POX de lujo y confort en el corazón de Equipetrol ✨ Ubicado en el piso 17 de la exclusiva Green Tower, este departamento POX Glam combina diseño moderno, decoración sofisticada y una vista panorámica única de Santa Cruz. Perfecto para viajeros de negocios, parejas o estadías de placer que buscan un espacio premium con todas las comodidades. En POX no solo alquilamos departamentos: te damos un hogar lejos de casa. Nuestro equipo está disponible 24/7 para ayudarte.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top Guest favourite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 53 reviews

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

Guest favourite
An open living area is displayed, featuring a modern design with light-toned floor tiles. A comfortable seating area includes a large gray sofa, black accent chairs, and an entertainment unit with a large TV. A kitchen bar with stools adds functionality to the space.
Apartment in Santa Cruz de la Sierra
4.92 out of 5 average rating, 13 reviews

Unique apartment in the best area!

Excepcional dpto. de 88 m2 en el corazón de Equipetrol. Lugar muy tranquilo para descansar o trabajar, pero a la vez cerca de la diversión. Pasarás una increíble estadía!! Con absolutamente todo, muy nuevo: amoblado y decorado, A/C, Wifi, Smartv 55' y 48', cocina completa, cama doble King, sofá cama Queen, lugar de lavado y secado propio, amplio parqueo gratuito en la entrada las 24 horas. Hermosa Piscina, sauna. Amplio balcón con linda vista a la ciudad.

Superhost
The image captures a clear blue pool with a gentle reflection of the nearby building and sky. A railing surrounds the pool area, providing a sense of safety and privacy. The peaceful ambiance is enhanced by the openness of the surrounding outdoor space.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 10 reviews

Casita Sirari

Unplug your worries in this spacious and serene space. Casita Sirari is in the heart of one of the most sought-after areas of Bolivia's most modern city. The city of Santa Cruz has an annual temperature between 20 and 38 degrees Celsius, the Casita Sirari pool is perfect for that vacation you deserve or also for the end of that work day you want to forget. Just steps from shops and restaurants, a private space is waiting for you.

Superhost
Cottage in Samaipata
4.96 out of 5 average rating, 25 reviews

EcoHouse · Pool · Nature · Tranquillity · Samaipata

A living-earth sanctuary on Samaipata Mountain. Hand-built, using natural materials and imbued with Bolivian spirit. Welcome to CASA CACTUS — fully equipped and customised for a stay surrounded by natural luxury. 🏊 Swimming pool · 🛜 Starlink · 🌿 Nature · Weekly and monthly DEALS *see below or contact us*. A space to truly rest. For writing. For slow cooking. To work online and offline. To look at the mountains without haste.

Superhost
Apartment in Santa Cruz de la Sierra
4.84 out of 5 average rating, 108 reviews

new and modern apartment

Welcome to your new home in Equipetrol, the best area of Santa Cruz! This new and modern apartment offers you a cozy and comfortable space, ideal for you to enjoy your stay, whether for work or rest. Located in the heart of Equipetrol, you'll be surrounded by everything you need: supermarkets, banks, shops, pharmacies, cafes, restaurants, church and the Ventura Mall. We invite you to enjoy an unforgettable stay.

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 39 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Popular amenities for Santa Cruz holiday rentals