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Holiday houses in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Apartment in Santa Cruz de la Sierra
4.91 out of 5 average rating, 155 reviews

Studio 518 - Luxury near Everything

Automatic access, 2 Air Conditioners, Washing Machine, Kitchen, Sofa and TV perfect for working all day with a green view from an 8th floor apartment in the most sought-after neighborhood in the city, Equipetrol. If you get bored you can use the pool at no cost, social areas, BBQ. If you get bored, you'll be 2 minutes away from supermarkets, pharmacies, blocks from Equipetrol's main square with renowned restaurants, 5 minutes from the Central Plaza or 5 minutes from Bolivia's largest shopping mall, Ventura Mall.

ValueLocationCondition

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 75 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

LocationValueIndoor spaces

Guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Apartment in Santa Cruz de la Sierra
4.96 out of 5 average rating, 55 reviews

Elegant family apartment in Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

ValueLocationLaundry

Superhost
Apartment in Santa Cruz de la Sierra
4.6 out of 5 average rating, 5 reviews

Balcony on 17th floor / Desk / Swimming pool / Gym

Meters from the 2nd ring, Equipetrol area, many restaurants, shops, supermarkets, gyms among others. With a balcony and a view of the 17th floor, pool, work area, gym and others in the social areas. Apartment with: -WiFi 100Mbps - Kitchen - Washing machine -Smart TV - Equipped bathroom - Bed - Pull-out sofa - 100 Mbps Wi-Fi In the building you will have: -swimming-pool - Gym - Sauna - Work area - Games area Live the experience and book ya!

ValueLocationHospitality

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Condo in Santa Cruz de la Sierra
4.85 out of 5 average rating, 298 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

ValueLocationSolo travel

Top Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

ValueLocationSleep quality

Guest favourite
Cottage in Samaipata
5.0 out of 5 average rating, 21 reviews

EcoHouse · Pool · Nature · Tranquillity · Samaipata

A living-earth sanctuary on Samaipata Mountain. Hand-built, using natural materials and imbued with Bolivian spirit. Welcome to CASA CACTUS — fully equipped and customised for a stay surrounded by natural luxury. 🏊 Swimming pool · 🛜 Starlink · 🌿 Nature · Weekly and monthly DEALS *see below or contact us*. A space to truly rest. For writing. For slow cooking. To work online and offline. To look at the mountains without haste.

FamilyLocationWi-Fi

Guest favourite
Apartment in Santa Cruz de la Sierra
4.92 out of 5 average rating, 25 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

LocationHospitalityAccuracy

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 25 reviews

Work and relax in Equipetrol, accessible and practical

New studio apartment in the heart of Equipetrol. Ideal for 2 people looking for comfort, style and an unbeatable location. It has an equipped kitchen, a desk to work or study, fast Wi-Fi and a giant Smart TV. The building offers a swimming pool, entertainment room with views, air conditioning and automatic check-in. Perfect for digital nomads, tourists or couples who want to enjoy Santa Cruz to the fullest.

LocationValueKitchen

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 37 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

FamilyLocationAmenities

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 18 reviews

Luxury apartment opposite the Hotel Yotaú

Enjoy a unique stay in the heart of Equipetrol, the best area in the city. Located on the 13th floor, this modern apartment offers a wonderful view and a private balcony for relaxing. Fully equipped for short or long stays, designed for your maximum comfort. Plus, enjoy exclusive luxury social areas that will make your experience even more special.

LocationGetting aroundComfort

Top Guest favourite
A modern living space is shown, featuring a round dining table surrounded by four chairs. A dark sofa with colorful cushions is positioned against a wall. The kitchen appliances and cabinetry are visible in the background, complemented by bright decor elements on the wall.
Apartment in Santa Cruz de la Sierra
4.99 out of 5 average rating, 70 reviews

Comfortable and modern apartment

Guests can enjoy a pleasant stay in an excellent location, the apartment's design, furniture and equipment suitable for a unique experience. It has a double bed and a sofa bed, A/C in the master bedroom and living room, a bathroom with a washing machine and all the amenities, and a kitchen equipped with everything you need. Internet speed: 35 Mbps

LocationValueAmenities

Popular amenities for Santa Cruz holiday rentals

Other great holiday rentals in Santa Cruz

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 9 reviews

Equipetrol Norte, 2 Bedrooms+Pool+Balcony

LocationComfortBathroom

Guest favourite
Apartment in Santa Cruz de la Sierra
4.95 out of 5 average rating, 19 reviews

Luxury apartment in Equipetrol | SKY Moon

LocationValueLaundry

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 11 reviews

Comfortable and Modern apartment in Equipetrol Fast Wifi

LocationIndoor spacesWalkability

Top Guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 54 reviews

Luxury and comfort in every detail

ValueLocationBarbecue

Top Guest favourite
An open-concept living area features a modern sofa arrangement alongside a sleek dining table. A light fixture hangs above, while large windows dressed with sheer curtains allow natural light to fill the space. Decorative plants add a touch of greenery.
Condo in Santa Cruz de la Sierra
5.0 out of 5 average rating, 32 reviews

Spacious apartment in Equipetrol

FamilyValueGetting around

Top Guest favourite
A modern interior is presented, featuring a cozy seating area with a dark sofa, complemented by a circular coffee table. A wooden divider offers separation from the sleeping area, where a spacious bed with neutral bedding is visible. Natural light fills the space from the nearby window.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 43 reviews

SkyLuxia New Equipetrol Apartment - Safe & Luxurious

LocationValueWi-Fi

Guest favourite
Apartment in Santa Cruz de la Sierra
4.96 out of 5 average rating, 46 reviews

The spectacular monoambiente in SkyElite

ValueLocationIndoor spaces

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 29 reviews

Equipetrol, Fantastic 2 Bedroom Apartment

FamilyLocationAir conditioning