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Holiday houses in Quartiere San Lorenzo, Rome

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Top-rated holiday rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome
4.94 out of 5 average rating, 251 reviews

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

Top Guest favourite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome
4.97 out of 5 average rating, 110 reviews

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, an aperitif at sunset or a moment of pure relaxation on our garden terrace: a welcoming oasis where you can recharge and immediately feel at home. Let yourself be enveloped by the authentic and youthful energy of the neighbourhood, among typical flavours, characteristic venues and atmospheres that know how to excite. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

Superhost
An open kitchen area combines modern and vintage elements, featuring a large island with a stovetop and hanging fixtures. A wooden dining table with four chairs is positioned nearby. Colorful books and decorative items are displayed on shelves, adding character to the space.
Apartment in Esquilino
4.95 out of 5 average rating, 368 reviews

Open Space with Terrace in Historic Pasta Factory

Located in the historic Pantanella Pasta Factory, this apartment is an eclectic and industrially designed open space, adorned with antique furniture, featuring a fully equipped kitchen, two double bedrooms, and a spacious bathroom with a double shower and sink. The terrace offers an escape from the hustle and bustle of the city and provides a relaxing oasis after a long day of sightseeing. Nearby: Basilica of San Giovanni, Scala Santa, the trendy Pigneto district, and the Termini train station.

Top Guest favourite
Loft in Rome
5 out of 5 average rating, 60 reviews

Fort 44

Immerse yourself in an unforgettable experience in this extraordinary two-storey loft, formerly an artist's studio and now transformed into an oasis of luxury and comfort.Perfect for couples, families or friends,this flat combines refined design and lovingly crafted details for a stay you will never forget. It consists of 2 bedrooms,3 bathroom,a fully equipped kitchen with a veranda overlooking the garden and a huge living room.Nestled in a neighbourhood full of life, restaurants and street art

Guest favourite
Apartment in Rome
5 out of 5 average rating, 18 reviews

Super flat with private parking and big garden

Scopri un rifugio perfetto per coppie e per famiglie nel vivace quartiere San Lorenzo. L’appartamento vanta un ingresso indipendente e un esclusivo giardino privato dove rilassarsi. Punto di forza: posto auto interno alla proprietà (non su strada) a costo fisso. A piedi raggiungerai in soli 15 minuti la Stazione Termini, l’Università La Sapienza e il Policlinico Umberto I, inoltre sono presenti numerose fermate bus e tram nei dintorni. Comfort, privacy e sicurezza in una posizione strategica.

Top Guest favourite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino
5 out of 5 average rating, 217 reviews

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

Guest favourite
Apartment in Rome
5 out of 5 average rating, 10 reviews

Charming Cozy Flat in San Lorenzo

Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. Perfect for couples or solo travellers! If requested, I am happy to arrange a transport from the airport.

Top Guest favourite
Holiday home in Rome
5 out of 5 average rating, 23 reviews

The King’s house•Central Rome•5 min from Termini

👑 Welcome to The King’s house — your cozy retreat in the heart of Rome! 👑 Located in the lively and authentic San Lorenzo neighborhood, this elegant apartment offers the perfect blend of comfort and character. Just a short walk from Termini Station, Rome’s main transport hub, it’s ideally positioned to explore the Eternal City with ease. Whether you're a couple, a family with kids, a group of friends, or remote workers, The King’s house is your perfect home base in Rome.

Top Guest favourite
A rustic kitchen features wooden countertops and modern appliances. Light filters through sheer curtains, framing a view of rooftops and greenery. A tray of cookies sits on the counter next to a kettle and a red coffee maker, creating a cozy cooking space.
Loft in Esquilino
4.98 out of 5 average rating, 163 reviews

Spectacular and Cozy Loft w/Terrace, near Termini

This one of a kind rustic yet elegant loft is full with details in wood, metal and stone, all handmade by Giulio, his owner. The fabulous terrace will take your breath away. How about some coffee with your slippers on while contemplating the Colosseum or watching the sun go down behind the Vatican shadow from the hut tub? Located minutes away from Termini Station but still a peaceful home. The access to the appartment is made by stairs. Breakfast it's on us!

Superhost
The living area features a light wood ceiling with exposed beams, creating an airy feel. A spacious sofa faces a wall-mounted smart TV. A dining table is set with plates and glasses. Large windows allow natural light, complemented by indoor plants for a refreshing touch.
Apartment in Rome
4.94 out of 5 average rating, 118 reviews

Oasi Piceni Apartment San Lorenzo

Oasi Piceni è il luogo ideale per coloro che desiderano vivere un'esperienza autentica nella Città Eterna. Situato nel cuore di San Lorenzo, un quartiere ricco di storia, arte e cultura, perfettamente collegato con tutti i luoghi d'interesse. L'appartamento è spazioso e dotato di tutti i comfort necessari per un soggiorno piacevole. Dispone di due camere matrimoniali, un soggiorno con divano, una cucina completamente attrezzata e una terrazza privata.

Superhost
Condo in Rome
4.93 out of 5 average rating, 107 reviews

Quiet Green View Apartment Near Termini

Appartamento affacciato sul verde in zona centrale, a due passi dalle principali stazioni, in palazzina d'epoca. Composto da una spaziosa camera da letto matrimoniale, soggiorno con due posti letto aggiuntivi in divano letto comodo, cucina attrezzata, bagno con doccia. Aria condizionata nella stanza da letto, finestre luminose e una sensazione molto bella di pace vi accoglieranno al vostro arrivo nel nostro appartamento. CIN: IT058091C2TGK7YYTV

Guest favourite
Condo in Rome
4.97 out of 5 average rating, 176 reviews

Apartment in Rome VestiniHouse

Cosy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. Live-in kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

Popular amenities for Quartiere San Lorenzo, Rome holiday rentals