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Holiday houses in Quartiere San Lorenzo, Rome

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Top-rated holiday rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome
4.94 out of 5 average rating, 251 reviews

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

LocationValueOutdoor spaces

Top Guest favourite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome
4.97 out of 5 average rating, 111 reviews

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, an aperitif at sunset or a moment of pure relaxation on our garden terrace: a welcoming oasis where you can recharge and immediately feel at home. Let yourself be enveloped by the authentic and youthful energy of the neighbourhood, among typical flavours, characteristic venues and atmospheres that know how to excite. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

ValueLocationAir conditioning

Top Guest favourite
A cozy living area features a comfortable sofa adorned with patterned cushions. A small table with blue chairs is positioned nearby, complemented by vibrant artwork on the walls. Natural light enters through an open window, creating a welcoming atmosphere.
Condo in Rome
4.94 out of 5 average rating, 180 reviews

central cozy & nice apartment, Rome

Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience

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Top Guest favourite
Condo in Rome
4.95 out of 5 average rating, 101 reviews

Thiago House S. Lorenzo, between Termini and La Sapienza

Stay in the heart of San Lorenzo, one of the most authentic and vibrant neighbourhoods in Rome, amidst street art, culture, history, clubs and the Roman atmosphere. Just 10 minutes from Termini, Thiago House is the perfect base for exploring the capital, returning each evening to a place that feels like home. Close to the historic Aurelian Walls and the prestigious La Sapienza University, it offers comfort and a strategic location that is ideal for studying, working or simply enjoying the city.

FamilyValueLong stay

Top Guest favourite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino
5.0 out of 5 average rating, 221 reviews

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

LocationFamilyView

Top Guest favourite
Holiday home in Rome
5.0 out of 5 average rating, 24 reviews

The King’s house•Central Rome•5 min from Termini

👑 Welcome to The King’s house — your cozy retreat in the heart of Rome! 👑 Located in the lively and authentic San Lorenzo neighborhood, this elegant apartment offers the perfect blend of comfort and character. Just a short walk from Termini Station, Rome’s main transport hub, it’s ideally positioned to explore the Eternal City with ease. Whether you're a couple, a family with kids, a group of friends, or remote workers, The King’s house is your perfect home base in Rome.

ValueFamilyHospitality

Superhost
Condo in Rome
4.93 out of 5 average rating, 107 reviews

Quiet Green View Apartment Near Termini

Apartment overlooking the greenery in a central area, a stone's throw from the main stations, in a period building. Comprising a spacious double bedroom, a living room with two additional beds in a comfortable sofa bed, a fully equipped kitchen and a bathroom with a shower. Air conditioning in the bedroom, bright windows and a very pleasant feeling of peace will welcome you upon your arrival in our apartment. National Identification Code: IT058091C2TGK7YYTV

LocationValueComfort

Top Guest favourite
A cozy living area is presented, featuring a round dining table surrounded by ornate chairs. A vintage wooden sideboard adds character, while a flat-screen TV is positioned nearby. Soft natural light enters through the window, illuminating the warm yellow walls and traditional decor.
Condo in Rome
4.97 out of 5 average rating, 62 reviews

"At my parents' house" in the heart of San Lorenzo

In the characteristic neighborhood of San Lorenzo you can stay "A casa dei miei", between tradition and modern comforts. All amenities are within reach. Restaurants, pizzerias, supermarkets, train station and public transport that will take you to the heart of Rome in no time. For example, the trams below the house will take you to the Colosseum, Circus Maximus, Trastevere or Villa Borghese in a short time. Please note: The price includes the tourist tax.

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Guest favourite
A thoughtfully arranged living area features a wooden dining table surrounded by chairs. A comfortable sofa with patterned cushions is present, alongside a small television and shelving. Natural light filters in through large windows, enhancing the inviting atmosphere.
Apartment in Rome
4.95 out of 5 average rating, 159 reviews

Apartment | Aedes Lunae | Roma city center

Delightful apartment located in the picturesque San Lorenzo district, a stone's throw from the city centre and minutes from the city's two main railway stations (Termini and Tiburtina). The ideal solution for couples, families and groups of friends. We will be happy to welcome you and make you feel at home. The apartment is equipped with all comforts...the ideal place to experience the wonders of the capital in the best way. CIN IT058091C2JVPTMKWW

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Top Guest favourite
Apartment in Rome
5.0 out of 5 average rating, 26 reviews

Giancarla Luxury Apartment Rome San LorenzoTermini

Elegance and Comfort in the Heart of Rome Experience an unforgettable stay in this refined flat in the heart of Rome. Just 10 minutes' walk from Termini Station and 2 km from the Colosseum and Roman Forum, the location is ideal for exploring the city. From Termini, reach Florence, Naples and the whole of Italy: art, culture and authentic flavours. Elegant, pet-friendly and equipped with every modern comfort. Book now and discover Rome in style!

LocationValueQuiet

Guest favourite
Condo in Rome
4.97 out of 5 average rating, 176 reviews

Apartment in Rome VestiniHouse

Cosy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. Live-in kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

LocationValueBreakfast

Top Guest favourite
Apartment in Rome
4.94 out of 5 average rating, 82 reviews

Bright penthouse with terrace

Our house is in the central district of San Lorenzo in Rome. It is located on the 4th floor of a building equipped with an elevator. It is perfect for 4 people as there is a double bedroom and one with two single beds. We enjoy an unobstructed view and incredible light, and from the house you can access the private upper terrace equipped for dining or just relaxing and enjoying the rooftops of Rome.

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