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Holiday houses in Quartiere San Lorenzo, Rome

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Top-rated holiday rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome
4.94 out of 5 average rating, 251 reviews

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

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Top Guest favourite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome
4.97 out of 5 average rating, 109 reviews

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, an aperitif at sunset or a moment of pure relaxation on our garden terrace: a welcoming oasis where you can recharge and immediately feel at home. Let yourself be enveloped by the authentic and youthful energy of the neighbourhood, among typical flavours, characteristic venues and atmospheres that know how to excite. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

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Guest favourite
Holiday home in Rome
4.98 out of 5 average rating, 92 reviews

Insolita Holiday Home - Termini Apartment

We are less than 2 km from Termini station, a short walk from the characteristic Tram 3! Hop on board and you can visit the wonders of Rome just like a true Roman: the Colosseum, Circus Maximus and other tourist attractions are within reach of our property, such as the Basilica of Santa Maria Maggiore or the Trevi Fountain. Our neighborhood is home to various "La Sapienza" University campuses, and we are a short distance from the Policlinico Umberto I medical center and the Istituto Superiore di Sanità.

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Top Guest favourite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino
5.0 out of 5 average rating, 217 reviews

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

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Guest favourite
Apartment in Rome
5.0 out of 5 average rating, 18 reviews

Super flat with private parking and big garden

Discover the perfect retreat for couples and families in the vibrant San Lorenzo neighbourhood. The apartment features a separate entrance and a dedicated private garden where you can relax. Advantage: parking space on the property (not on the street) at a fixed cost. You can walk to Termini Station, La Sapienza University and the Policlinico Umberto I in just 15 minutes, and there are also numerous bus and tram stops nearby. Comfort, privacy and security in a convenient location.

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Guest favourite
Apartment in Rome
5.0 out of 5 average rating, 10 reviews

Charming Cozy Flat in San Lorenzo

Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. Perfect for couples or solo travellers! If requested, I am happy to arrange a transport from the airport.

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Top Guest favourite
Holiday home in Rome
5.0 out of 5 average rating, 23 reviews

The King’s house•Central Rome•5 min from Termini

👑 Welcome to The King’s house — your cozy retreat in the heart of Rome! 👑 Located in the lively and authentic San Lorenzo neighborhood, this elegant apartment offers the perfect blend of comfort and character. Just a short walk from Termini Station, Rome’s main transport hub, it’s ideally positioned to explore the Eternal City with ease. Whether you're a couple, a family with kids, a group of friends, or remote workers, The King’s house is your perfect home base in Rome.

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Superhost
Condo in Rome
4.93 out of 5 average rating, 107 reviews

Quiet Green View Apartment Near Termini

Apartment overlooking the greenery in a central area, a stone's throw from the main stations, in a period building. Comprising a spacious double bedroom, a living room with two additional beds in a comfortable sofa bed, a fully equipped kitchen and a bathroom with a shower. Air conditioning in the bedroom, bright windows and a very pleasant feeling of peace will welcome you upon your arrival in our apartment. National Identification Code: IT058091C2TGK7YYTV

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Superhost
A spacious bedroom features a neutral color palette with soft lighting. A comfortable bed is adorned with neatly arranged towels and decorative cushions. Framed artwork is displayed on the walls, and a bouquet of flowers adds a touch of elegance. Nightstands are positioned on either side.
Apartment in Rome
4.92 out of 5 average rating, 148 reviews

White Flat Dalmati

Located in Rome, in the lively and characteristic historic district of San Lorenzo, the White flat Dalmati is a spacious apartment equipped with all amenities for a pleasant stay. The apartment is about a 15/20-minute walk from Termini station with two bus lines to and from the station that stop less than 5 minutes away. In 15 minutes, with the same buses you can get to the heart of the city. La Sapienza University and the CNR are less than 200 meters away.

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Guest favourite
Condo in Rome
4.97 out of 5 average rating, 176 reviews

Apartment in Rome VestiniHouse

Cosy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. Live-in kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

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Superhost
The living area features a light wood ceiling with exposed beams, creating an airy feel. A spacious sofa faces a wall-mounted smart TV. A dining table is set with plates and glasses. Large windows allow natural light, complemented by indoor plants for a refreshing touch.
Apartment in Rome
4.94 out of 5 average rating, 118 reviews

Oasi Piceni Apartment San Lorenzo

Oasi Piceni is the ideal place for those who want to live an authentic experience in the Eternal City. Located in the heart of San Lorenzo, a neighborhood rich in history, art and culture, perfectly connected to all places of interest. The apartment is spacious and equipped with all the necessary amenities for a pleasant stay. It has two double bedrooms, a living room with sofa, a fully equipped kitchen and a private terrace.

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Top Guest favourite
Apartment in Rome
4.94 out of 5 average rating, 80 reviews

Bright penthouse with terrace

Our house is in the central district of San Lorenzo in Rome. It is located on the 4th floor of a building equipped with an elevator. It is perfect for 4 people as there is a double bedroom and one with two single beds. We enjoy an unobstructed view and incredible light, and from the house you can access the private upper terrace equipped for dining or just relaxing and enjoying the rooftops of Rome.

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