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Holiday houses in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Tiny home in Cocorná
5 out of 5 average rating, 55 reviews

lovely cabin with sauna, jacuzzi and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

Top Guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 655 reviews

Foresta: Modern cabin overlooking the Rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us, or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the Rock and do kayaking, jet-skiing, wakeboarding, sailing, paraglading, horseback riding, hiking, helicopter tours or ATV rides. You choose!

Luxe
Home in Medellín
4.99 out of 5 average rating, 123 reviews

Casa Alba Luxury Villa-Pool-15min to Provenza

1. Luxury Retreat: Unparalleled seclusion in Medellin. 2. Stunning Views: Overlooking Poblado 3. Privacy: Total escape from daily life. 4. Convenient Access: Easy access to the airport. 5. Heated Pool: Year-round relaxation. 6. Jacuzzi: Private and calming atmosphere. 7. Outdoor Amenities: Fireplace & kitchen for al fresco dining. 8. Air Conditioning: Each bedroom offers AC 9. Nightlife: Close to vibrant city nightlife. 15mins drive 10. Daily housekeeping

Top Guest favourite
An outdoor seating area features two woven armchairs and a small table, overlooking a stunning natural landscape with distant hills and sparkling lake waters. A wooden hot tub is positioned nearby, with safety glass panels enhancing the unobstructed views of the surrounding scenery.
Apartment in El Peñol
4.99 out of 5 average rating, 115 reviews

Welcome to Ecolodge Paradise at Montecielo

Escape to tranquility in this serene mountain hideaway overlooking the sparkling waters of one of Colombia's most beautiful lakes. Nestled in the lush hills of Guatapé, our cozy retreat offers breathtaking panoramic views, fresh mountain air, and the perfect setting to unwind and recharge. Wake up to birdsong and misty sunrises, sip your morning coffee on the terrace, and spend your days exploring the vibrant town of Guatapé or simply relaxing in the peaceful embrace of nature.

Guest favourite
Cabin in El Carmen de Viboral
4.93 out of 5 average rating, 75 reviews

Espi Ritual

Step into tranquility and reconnect with nature in this serene Llano Grando cabin. Soak up the patio sun, immerse yourself in the beautiful garden, or spot countless bird species on the sun-deck overlooking the pond. This cabin is equipped with WiFi, a full kitchen, an asador, and a private entrance. The perfect location for a peaceful solo trip, charming romantic getaway, or unique family adventure. 15 minutes from charming San Antonia and near restaurants and shopping

Top Guest favourite
A modern house is displayed with expansive glass walls, revealing a generous patio area. A private jacuzzi is surrounded by seating arrangements and tropical plants. The second-floor terrace features outdoor dining furniture, enhancing the view of the surrounding landscape.
Cottage in El Peñol
4.98 out of 5 average rating, 117 reviews

House*A/C*Jacuzzi/Wi-Fi*Family*Dam/Guatapé

Enjoy a unique experience in this modern home with a panoramic view of the Guatapé dam. For families and groups of friends looking for rest, comfort, with modern design, large terraces and a breathtaking view over the dam. ✔ Second-floor rooms with air conditioning ✔ Direct Dam Access ✔ Private jacuzzi. ✔ Bright and spacious BBQ ✔ Terrace ✔ Wifi ✔ Private parking Experience unforgettable moments surrounded by comfort and tranquillity, with the attractions of Guatape.

Top Guest favourite
Cabin in Rionegro
5 out of 5 average rating, 40 reviews

Selvva suites | luxury cabin in a forest + jacuzzi

Escape to SELVVA SUITES, a luxury retreat immersed in the tranquility of a native forest, just 50 minutes from Medellín. Located on the Llanogrande–La Ceja road, only 15 minutes from Llanogrande mall and 20 minutes from JMC Airport in Rionegro. Enjoy a King-size bed and a private jacuzzi surrounded by nature. Private parking with easy access for any type of vehicle. ⚠️ ✈️We are in an area with air traffic, and airplane noise can be heard. 🐾 Pet friendly

Top Guest favourite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.95 out of 5 average rating, 56 reviews

Country house, excellent location, beautiful view!

We invite you to enjoy a beautiful space surrounded by nature, with all the comforts you need to relax and unwind. You will feel like you are right at home. Ideal place for working remotely (digital nomads) and for long stays. Just 10 minutes from La Ceja, 45 minutes from the international airport and 1 hour from Medellín. Pets are welcome. We also offer yoga classes, Ayurvedic therapies (Abhyanga/Swedana) and tennis lessons. Perfect place for "slow" tourism!

Top Guest favourite
Farm stay in Cocorná
4.98 out of 5 average rating, 50 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top Guest favourite
Cabin in Rionegro
4.98 out of 5 average rating, 120 reviews

Nature & View | Cabin with Jacuzzi and nature

Enjoy an unforgettable experience in our private cabin, located just 8 minutes from José María Córdova International Airport. Enjoy a panoramic view of the city and relax in your private Jacuzzi. The cabin is equipped with a full kitchen, fast wifi, workspace and self check-in. You will find several nearby restaurants with home delivery, and inside the accommodation we have drinks and snacks to buy. 🚘 Trusted Uber driver

Top Guest favourite
Cabin in El Peñol
4.96 out of 5 average rating, 156 reviews

Sun Palm Cabin: Nature and Comfort in El Peñol!

Discover an exceptional retreat surrounded by nature, where every detail is designed to offer you an unforgettable experience. This cabin combines elegance and comfort. Relax in your private jacuzzi while enjoying breathtaking panoramic views in a serene environment. Perfect for a romantic getaway or rejuvenating vacation, you will find the ideal harmony between privacy and natural beauty. Your perfect escape awaits!

Guest favourite
Farm stay in Rionegro
4.95 out of 5 average rating, 306 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia