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Holiday houses in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A spacious wooden bedroom features a king bed adorned with light bedding, complemented by textured walls and a rustic wood ceiling. A colorful hammock hangs across the room, and natural light filters in through a window, enhancing the cozy ambiance.
Treehouse in Retiro
4.88 out of 5 average rating, 103 reviews

A wooden cabin in the El Retiro Antioquia forest

Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Top Guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 584 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Guest favourite
Tiny home in Cocorná
5 out of 5 average rating, 9 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Top Guest favourite
Condo in El Poblado
4.97 out of 5 average rating, 176 reviews

[C] Poblado Heights|19th FL View|AC|Spa|Sauna

RECENTLY RENOVATED -High-speed internet great for remote work -Brand new A/C -Fully renovated Industrial design apartment -King size bed -Breathtaking views of Medellín (trust me, worthwhile to stay here) -19th floor -Unbeatable location in Poblado near to Provenza and Lleras Park -Modern amenities -Spacious living area -Smart TV x 2 -Fully equipped kitchen -Washer & Dryer Tower -Pool -Gym -Coworking space -Restaurant inside the building -Private parking -Self check-in -24/7 Security

Guest favourite
Aerial view of three triangular-roofed cabins surrounded by lush greenery. A wooden deck features a private jacuzzi, while modern seating is arranged thoughtfully outdoors. The structure's glass doors allow for natural light, enhancing the serene ambiance created by the surrounding trees.
Tiny home in El Peñol
4.9 out of 5 average rating, 217 reviews

Lux cabin+ jacuzzi, kayak & lake view • Breakfast

🥘 Room service with local cuisine made from fresh ingredients grown in our garden and prepared on the spot 🍳 Breakfast included 🌐 High-speed fiber WiFi to stay connected 🛁 Private jacuzzi with stunning lake view 🔥 Gas fireplace for cozy nights 🚣‍♀️ Kayak and paddle board included to explore the lake 🐦 Birdwatching right from your terrace 📍 Located across the lake from one of the region’s most iconic estates, only 15 minutes from La Piedra del Peñol and 18 minutes from Guatapé.

Guest favourite
A spacious living area showcases high wooden ceilings with exposed beams. Comfortable seating includes two plush sofas and two armchairs arranged around a coffee table. A television is mounted on the wall above a light wooden console. Potted plants add greenery to the setting.
Apartment in la union
5 out of 5 average rating, 11 reviews

Cozy Apto La Union. (Ant)

Create unforgettable memories in this unique and family home, with an exceptional location and everything you need to have a comfortable stay in this magical town of the Antioqueño East. This space has been created to offer comfort and tranquility, ideal for travelers and families. The accommodation has a main and a secondary bedroom with a cabin and an auxiliary bed, private bathroom, fully equipped kitchen and a living room with sofa Cama, ideal space to share.

Top Guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 104 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Top Guest favourite
Cabin in Rionegro
4.95 out of 5 average rating, 307 reviews

Cabin 8 minutes from JMC International Airport

Nature & View just 8 minutes from JMC Airport Ideal for couples or travellers in transit. Our cabin overlooks the valley, quiet atmosphere, self check-in, equipped kitchen, fast wifi, and all the amenities to relax. For your convenience, there are restaurants with home delivery and you can buy cold drinks and snacks at the property whenever you need them. 🚘 Trusted Uber driver Relax, order your favourite food and enjoy the view. Book your date!

Top Guest favourite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.96 out of 5 average rating, 290 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend or work remote in a distraction-free environment. Wake up to the singing of the birds at sunrise and enjoy a fire on the deck at sunset. In Retiro Cabin you will have total independence and an unparalleled view of the countryside in the Antioquia East.

Top Guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 300 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Guest favourite
Cabin in Colmenas
5 out of 5 average rating, 7 reviews

Mountain retreat: sounds of silence # 1

Discover tranquillity in this cosy hideaway surrounded by nature. Our cabin, built in wood and with a modern and warm design, offers a perfect space to rest, read, contemplate the landscape or simply enjoy the silence. From your terrace or large windows, you can admire endless mountains, golden sunsets and clear skies that invite you to relax. Inside you will find a comfortable and well-equipped atmosphere.

Top Guest favourite
A bright workspace features a wooden desk with a comfortable ergonomic chair and modern lamp. A hammock hangs nearby, surrounded by lush greenery. Large glass windows invite natural light and offer scenic views of the surrounding trees, creating a serene and productive atmosphere.
Cabin in Santa Elena
4.99 out of 5 average rating, 232 reviews

Tree Life Cabin, Saint Helena

A place to be in touch with nature from the comfort. Experience rest and tranquility in a space that opens up among the trees. Enjoy a landscape that changes between fog, rain, and a gentle sun. Santa Elena is a rural mountain area outside of Medellín, 19 km from downtown or 13 km from JMC Airport. The cabin is located near bus routes, restaurants, mini-markets, forest trails, and tourist attractions.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia