Holiday houses in Mayo Lake

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Top-rated holiday rentals in Mayo Lake

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Guest favourite
A spacious living area is furnished with a dark sectional sofa and a wooden coffee table atop a neutral area rug. Light fixtures hang from the ceiling, and a warm welcome sign is mounted on the wall. The open layout provides a view into the dining space.
Home in Alton
4.94 out of 5 average rating, 199 reviews

8 mi. to VIR! 18 min to Danville, South Boston, Va

Spacious, clean, & relaxing, this home is less than 8 miles from VIR and 18 mi to Danville, South Boston, or Roxboro. The listing is on one floor level to accommodate those with mobility issues. High-speed Starlink WiFi. Bedrooms provide linens/pillows/blankets. Bathrooms provide towels & necessities. Full kitchen w/coffee. Oversized paved parking with easy accessibility. Perfect for trailers/multiple large vehicles. Close to hwy, may want to pack earplugs. Strict no smoking or pets please.

Top Guest favourite
A modern tiny home features a dark exterior and large windows, set on a gravel area. A spacious wooden deck is adorned with seating and a fire pit, while smoke gently rises from a nearby outdoor grill. Lush greenery surrounds the retreat.
Tiny home in Efland
5 out of 5 average rating, 307 reviews

Timberwood Tiny Home

Timberwood Tiny Home is a place to rest your head & heart in Efland, North Carolina. The peaceful retreat is down a country road approximately 10-minutes from downtown Hillsborough. The 200 square foot tiny home is on a private corner of 8-acres shared with our main house. It features Scandinavian-style details, two beds, a spacious porch, abundant natural light, a wood-fired hot tub, barrel sauna, cold plunge, and more. There are features of the home that may make it unsuitable for children.

Top Guest favourite
A wooden dock extends into calm waters, reflecting the soft colors of dusk. Lush greenery surrounds the lake, with trees visible along the shoreline. A gentle rise in the landscape creates a serene backdrop, while the moonlight begins to peek through the evening sky.
Home in Clarksville
4.93 out of 5 average rating, 136 reviews

Kerr Lake Amazing Views, Private Dock, Quiet

Peaceful lakefront retreat: Private dock, table, and new solar-lit umbrella (7/28/25). Amenities include a new gas grill (7/28/25), paddleboard, canoe, kayak, cornhole, hammock, firepit, puzzles, books, and games. Enjoy a large deck with two tables and a screened porch with couch—perfect for morning coffee. The home features 3 bedrooms, a loft, 3 full baths, and a dedicated workspace. Ideal for families, friends, or fishing trips. Driveway fits 5 trucks with trailers; boat launch 2 miles away.

Top Guest favourite
An open living space is revealed from an elevated view, displaying a cozy seating area beside a stone fireplace. Large windows offer scenic views of the lake, while a wooden deck with outdoor seating is visible beyond. Natural light fills the room, highlighting the warm wood flooring.
Home in Roxboro
4.98 out of 5 average rating, 93 reviews

Private Lakefront Paradise - Paddleboards & Kayaks

*Dogs only allowed with approval from owner. Scroll down to read more.* Beautiful 3 bedroom, 3 bath home on Mayo Lake in Roxboro, NC. Incredible views of the lake. You rarely see anyone on our secluded cove. You can swim, fish, paddleboard, kayak or tie up your boat. House is only 5 minutes from the marina and comes with paddleboards and kayaks and has a fire pit. Large, open kitchen, family room/ entertainment room, ping pong table, and jetted tub. Close to hiking, fine dining, and VIR.

Top Guest favourite
Two turquoise lounge chairs are positioned on a wooden dock, providing a serene view of the calm water and surrounding trees. The leaves display autumn hues, reflecting the season's changing colors. A railing runs along the dock, enhancing safety and accessibility to the water.
Cottage in Leasburg
4.81 out of 5 average rating, 202 reviews

Hyco Hideaway

A lakeside retreat to call your own (at least for a little while). This two bedroom, one bath scenic cottage sits on approximately 250 feet of waterfront where you have a lake view from the huge screen porch. An open floor plan with fully furnished kitchen, beds, and full bath will make this an exceptional getaway. Nestled deep in the forest, the dock is accessible by a path that is steep in places or staircase plus steep timber steps with no handrail. Water depth at dock is shallow.

Top Guest favourite
A clear view of the luxurious hot tub is presented, framed by wooden structure and surrounded by tall, mature trees. The serene landscape beyond showcases a distant barn and open pastures under a bright blue sky with wispy clouds.
Tiny home in Hillsborough
4.96 out of 5 average rating, 193 reviews

Peaceful tiny house retreat on 30 acre farm

This new tiny house is nestled amongst mature hardwood trees on a 30 acre working family farm in Hillsborough. Quiet your mind and restore your body in the luxurious hot tub or warm up by the cozy fire-pit. Under 10 miles to Hillsborough or Durham, and their many restaurants, breweries and shops. Enjoy the privacy of two secluded wooded acres, surrounded by the sights and sounds of our farm, where we are growing fruits, veggies and mushrooms & caring for our animals and pastures.

Top Guest favourite
A spacious waterfront home is nestled among tall trees, with a path leading to Mayo Lake. Sunlight filters through the leaves, casting gentle shadows. The wrap-around porch is partially visible, extending towards the lake for serene views.
Cabin in Roxboro
4.88 out of 5 average rating, 190 reviews

Water Front Lake House!

Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water and dock, hammock and fire pit. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Guest favourite
The interior space features a warm wooden ceiling and a large Smart TV mounted on the wall. A glass sliding door offers views of the lush greenery outside and the lake beyond, leading to a deck with outdoor seating.
Home in Leasburg
4.93 out of 5 average rating, 168 reviews

Mountain cabin feel on Hyco Lake.

Unwind at this hidden jewel tucked in the woods on Hyco Lake. Forget tiny houses, this “Skinny House” boasts two bedrooms, two baths, a spacious open floor plan, cedar ceilings, fully equipped kitchen, gas grill, solo stove, laundry room. Indoor and outdoor living that is large enough for six adults. Floating dock invites you to spend your days on the lake - swimming, fishing, boating, or just soaking in the views. Canoe, Kayaks, Paddle-boards & life vests provided!

Superhost
A wooden dock extends over calm waters, featuring a single chair positioned at the edge. Reflections of colorful autumn foliage are visible in the lake, creating a serene natural setting under a clear blue sky.
Home in Roxboro
4.9 out of 5 average rating, 142 reviews

Lakefront Oasis-HotTub | GameRoom | Kayaks | Dock

At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!

Superhost
A serene lakeside view captures the early morning mist hovering over the calm water. Soft hues of orange and yellow reflect on the surface, while the silhouette of trees outlines the horizon. A wooden dock extends into the scene, inviting peaceful moments by the water.
Home in Prospect Hill
4.84 out of 5 average rating, 178 reviews

Lakefront Hygge: Dock|Marine Hammock|Screen Porch

Discover a peaceful haven on the water in Prospect Hill! This stylish Scandinavian Modern house boasts a private dock on a quiet reservoir, offering a serene escape. Enjoy the natural beauty and tranquility, while still being a short drive to Hillsborough, Chapel Hill, Durham, Raleigh, Greensboro, Charlotte and Danville. With a cozy, inviting interior, and abundant places to enjoy the outdoors, this waterfront property is the perfect place to "press pause".

Top Guest favourite
A serene lake is observed from a wooden dock, with calm waters reflecting surrounding greenery and a clear sky. The shoreline is lined with trees, creating a tranquil atmosphere. Ripples gently disturb the water's surface, highlighting the lake's peaceful environment.
Home in Roxboro
4.98 out of 5 average rating, 107 reviews

Long’s Lakehouse

Relax with the whole family at this peaceful waterfront property. It is a 2 bedroom, 2 bathroom house with one king bed, one queen bed, and a pull out sofa! The kitchen is fully stocked with a coffee pot, utensils, pizza pan, crock pot, skillet, pots , pans, baking sheets, toaster, oven and microwave! Bedrooms and living room have smart tvs. WiFi available! Enjoy the kayaks, lots of fishing, grilling, and fire pit! There is something for here for everyone!

Top Guest favourite
The entrance to the Silo Suite is highlighted by an inviting wooden door with large glass panes. A sign identifying the suite is displayed prominently next to the door. Natural light reflects off the exterior, enhancing the contemporary design.
Tiny home in Durham
4.99 out of 5 average rating, 116 reviews

Rivers Edge Farm Silo Suite

Enjoy the sounds of nature when you stay in this unique place. The Silo Suite tiny home is nestled in a private area by the silo on our horse farm. This location is fully equipped with all the comforts of home. Loads of day hiking opportunities whether your planning a day trip, weekend getaway or week long vacation there is no shortage of things to do and see. Come enjoy our country setting that’s only minutes away from Duke and Downtown.

Popular amenities for Mayo Lake holiday rentals