
Family-friendly holiday rentals in Little Italy
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Little Italy

Total holiday rentals
Explore 180 holiday rentals in Little Italy

Nightly prices starting at
Little Italy holiday rentals start at $128 AUD per night before taxes and fees

Verified guest reviews
Over 14,910 verified reviews to help you choose

Pet-friendly accommodation
Find 70 rentals that welcome pets

Holiday rentals with a pool
40 properties feature pools

Rentals with dedicated workspaces
120 properties have a dedicated workspace

Wi-Fi availability
180 of Little Italy holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Little Italy rentals

4.8 Average rating
Little Italy stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated family-friendly rentals in Little Italy
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Contemporary, Fully Renovated Loft in Little Italy
Book this spectacular contemporary loft with 25 foot ceilings & views! The loft is in an area with a 9.8/10 walk score & known for having the best restaurants, bars &shops. The unit is newly renovated & meticulously designed with bright windows, contemporary high-end furnishings & an everyday spa inspired bathroom. Only steps from the waterfront, you decide if you want to enjoy cocktails & cuisine in the night scene or relax all day walking along the harbor. Free parking spot with access to all.
FamilyKitchenLocation
4.79 out of 5 average rating, 218 reviews
Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.
FamilyKitchenParking
4.96 out of 5 average rating, 513 reviews
Little Italy Historical
This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.
Indoor spacesKitchenHeating
4.98 out of 5 average rating, 116 reviews
Explore Little Italy from this Gorgeous Mini Villa
La Scala rises from the center of Villa Little Italy in the heart of San Diego’s most popular restaurant and entertainment district. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.
KitchenFamilyOutdoor spaces
4.88 out of 5 average rating, 342 reviews
Modern Inner City Pad w/ Patio | Walk Everywhere!
Enjoy everything Little Italy has to offer right on your doorstep from this bright, light and inviting apt. Open the floor-to-ceiling glass doors and let the sounds of the city in as you relax on the lounge and shaded patio. Cook in the modern kitchen, feel pampered in the luxe bathroom, then retire to the chic, king bedroom. Explore quaint streets, cafes, gelato shops, and charming trattorias just steps away then discover downtown, Balboa Park, & the Gaslamp Qtr, an easy 5/10 min drive away!
Indoor spacesFamilyCheck-in
4.88 out of 5 average rating, 209 reviews
Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.
Indoor spacesKitchenCheckout
4.96 out of 5 average rating, 384 reviews
Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!
FamilyIndoor spacesLocation
4.94 out of 5 average rating, 260 reviews
City View Banker's Hill
A beautifully renovated 2-bedroom, 1.5-bathroom craftsman-style duplex is perfectly situated in the heart of Bankers Hill. The perfect blend of classic craftsmanship and modern amenities in this beautifully restored home. Minutes away from San Diego's top attractions, including Balboa Park, Little Italy, and the vibrant Gaslamp Quarter. Two comfortable bedrooms provide a peaceful retreat. Fully equipped kitchen with new appliances. A perfect place to enjoy all that San Diego has to offer.
FamilyIndoor spacesLocation
4.92 out of 5 average rating, 114 reviews
Artifact Inn - Historic Deluxe Studio in Downtown
The Artifact Inn professionally managed by NOVIQ. Unwind with ease in this chic Gaslamp studio offering a queen bed, air mattress, Smart TV, and free WiFi. Cook meals in the full kitchen, refresh with in-unit laundry, and enjoy climate control with central AC. With thoughtful touches and professional cleaning, this stylish retreat provides both comfort and security. Perfectly situated near Petco Park and top attractions, it’s ideal for those seeking a central and vibrant San Diego escape.
Indoor spacesKitchenLayout
4.9 out of 5 average rating, 117 reviews
#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
Indoor spacesFamilyTV
4.9 out of 5 average rating, 767 reviews
Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.
FamilyKitchenWalkability
4.95 out of 5 average rating, 168 reviews
Room D at The Dutra Inn - Little Italy
“This is the room that all the locals book. I couldn’t figure out why, so one day I decided to ask a guest. ‘I’ve walked past here a million times, and I just had to see what was behind these doors,’ he replied, as if it were obvious.” Our 20 ft., 100-year-old naval train station doors do seem like have a story to tell. Salvaged and repurposed here in our only street-level loft, they bring in the light and life of downtown San Diego. IG: @the.dutra
FamilyKitchenAccuracy
4.94 out of 5 average rating, 539 reviewsPopular amenities for Little Italy family-friendly rentals
Family-friendly home rentals with a hot tub

Beautiful Historic Home and Gardens Near Downtown!
FamilyKitchenBackyard
4.97 out of 5 average rating, 300 reviews
1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
Indoor spacesFamilyQuiet
4.94 out of 5 average rating, 103 reviews
2 Bed Hidden Gem | Hot Tub, Parking | Midtown SD
Indoor spacesKitchenCheckout
4.9 out of 5 average rating, 224 reviews
Amazing Zen Villa! HotTub LittleItaly Convention C
FamilyIndoor spacesOutdoor spaces
4.91 out of 5 average rating, 304 reviews
Pool Oasis in Central Hillcrest by Park/Zoo
Indoor spacesFamilyLayout
4.92 out of 5 average rating, 185 reviews
Lionhead - Private Boutique Home
KitchenIndoor spacesBackyard
4.93 out of 5 average rating, 293 reviews
Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
Indoor spacesFamilyCondition
4.96 out of 5 average rating, 180 reviews
Cozy home central to beaches & attractions
FamilyIndoor spacesLong stay
4.92 out of 5 average rating, 200 reviewsFamily- and pet-friendly home rentals

Beautiful Canyon Cottage located on a huge lot
Indoor spacesKitchenSleep quality
4.96 out of 5 average rating, 164 reviews
The Cozy Craftsman
FamilyIndoor spacesQuiet
4.96 out of 5 average rating, 186 reviews
NEW Stylish of Downtown Little Italy w Parking/AC
KitchenFamilyAccess
4.83 out of 5 average rating, 156 reviews
Quiet studio: King bed, AC, Washer
KitchenIndoor spacesComfort
4.8 out of 5 average rating, 569 reviews
Modern Bankers Hill Studio on Maple Canyon
Indoor spacesFamilyDecor
4.84 out of 5 average rating, 164 reviews
Central Little Italy Bayview House
FamilyKitchenHospitality
4.9 out of 5 average rating, 167 reviews
Little Italy 2BR Loft Near Waterfront & Convention
Indoor spacesFamilyWi-Fi
4.83 out of 5 average rating, 228 reviews
Downtown Dream 4
FamilyKitchenView
4.79 out of 5 average rating, 121 reviewsFamily-friendly home rentals with a pool

1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa
Indoor spacesKitchenSolo travel
4.99 out of 5 average rating, 193 reviews
Designer Luxury Rental With Pool
Indoor spacesFamilyDecor
4.94 out of 5 average rating, 151 reviews
Hillcrest canyon home casita with pool access
KitchenFamilyShared spaces
4.89 out of 5 average rating, 143 reviews
Family Oasis w/ Heated Pool
FamilyKitchenBackyard
4.98 out of 5 average rating, 125 reviews
Your Modern Lux Pool Resort in the Heart of SD
KitchenIndoor spacesPool
4.9 out of 5 average rating, 189 reviews
Heart of San Diego in Old Town. Private Oasis 6
Indoor spacesFamilySleep quality
4.98 out of 5 average rating, 124 reviews
Modern Central SD Home w/ Pool & Spa Near Beach
KitchenFamilyWalkability
4.92 out of 5 average rating, 131 reviews
Lux Villa: Heated Pool & Sauna
KitchenFamilyLaundry
4.96 out of 5 average rating, 139 reviewsDestinations to explore
- Rentals with a sauna Little Italy
- Pet-friendly rentals Little Italy
- Rentals with beach access Little Italy
- Apartment rentals Little Italy
- Rentals with a hot tub Little Italy
- Waterfront rentals Little Italy
- Condo rentals Little Italy
- House rentals Little Italy
- Hotel rooms Little Italy
- Loft rentals Little Italy
- Rentals with breakfast Little Italy
- Rentals with pools Little Italy
- Family-friendly rentals San Diego
- Family-friendly rentals San Diego County
- Family-friendly rentals California
- Family-friendly rentals United States
- SeaWorld San Diego
- Rosarito Beach
- Coronado Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Oceanside City Beach
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Liberty Station





