
Holiday houses in Isola
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Isola
Guests agree: these stays are highly rated for location, cleanliness and more.

Maisonette, 14 San Paolo
Maisonette San Paolo 14, an exceptionally elegant suite, is housed in a historic 17th-century building adjacent to the Temple of Apollo, following a meticulous renovation focused on comfort and design. As soon as you enter, you are enveloped by a positive energy that conveys serenity and harmony, perfect for relaxing. Featuring a kitchen, an ensuite bedroom and an elegant outdoor patio where you can enjoy unforgettable moments. The intimate atmosphere of this property makes it ideal for couples and for the most discerning guests.
LocationAccuracyLong stay

Private Heated Pool•Sea View•Walk to Beach•Shati
Private heated pool (30°C) all year round. Just steps from a pristine white sandy beach. Breathtaking sea views, total privacy and tropical gardens. Signature design and refined luxury. The ideal base to explore Eastern Sicily. Iconic architecture by C. Calvagna. Premium sleep with toppers and curated pillow menu. Fireplace, fire pit and heated pool. Top-level services and tailor-made experiences. On request: private chef, In-villa massage, daily housekeeper, babysitting and bespoke experiences
LocationFamilyComfort

Penthouse Lady Packard
Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.
LocationValueIndoor spaces

Sea-View Loft. Elegant & Bright Old Town Retreat
Experience the timeless charm of Ortigia from this elegant 80 m² sea-view apartment. Perfect for couples, families, or small groups, Suite 18 blends authentic Sicilian character with modern comfort, just steps from the island’s iconic landmarks. Wake up to breathtaking harbour views from your private balcony, relax in the bright open-plan living area, and enjoy a fully equipped kitchen, a peaceful bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, heating and lift access.
ValueFamilyTV

Island – for those who love nature, sea and culture
The house, surrounded by fields and with a beautiful view of the sea of Plemmirio, is located in a natural area of extraordinary beauty and tranquility. It is suitable and open to everyone NB: A car is essential. Upstairs, there is a small independent apartment belonging to other owners. Nearest sea: Scala Ruiz 350 m on foot. It is a place where you can forget about everything knowing, however, that if you want, in ten minutes you are in Syracuse, with its culture and worldly life.
LocationFamilyQuiet

Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach
On a quiet road a few steps away from the sea and Cala Rossa beach, this luminous independent 3 beds and 3 bathrooms townhouse, has been designed to make your holiday in Ortigia unforgettable. "CASA SANTINI" is the product of our family's love for Ortigia and the vision of our local Architect Ignazio. The house has been fully renovated with meticulous attention to details, keeping the old features and adding all comforts and modern elements to create an elegant and calming space.
FamilyLocationSleep quality

Casa Carlotta - Stunning uninterrupted sea views
In 2022 Casa Carlotta has undergone a full and radical renovation to enhance the beauty of the position of the house and to increase the comfort for our guests. We are happy to share the results with our guests. In 2024 we have further upgraded the kitchen area. Casa Carlotta offers a stunning location; an uninterrupted 180-degree sea view of the mediterranean, enjoyed from the large terrace that surrounds the house, and access to the sea which is just a few short steps away.
FamilyValueBarbecue

Allisola Country Villa - casa Carrubo
Allìsola is an ancient Sicilian residence, nestled in the beautiful protected area of Plemmirio, a few kilometers from Syracuse. From a single body were obtained three refined houses, independent of each other, inserted in a single large outdoor space with green corners, terraces and a relaxing pool. There is a private terrace with outdoor furniture, a large garden with a swimming pool shared with guests of the property, and a parking lot surrounded by an olive grove
LocationFamilyLaundry

Timeless: Detached villa with infinity pool
In the heart of the Plemmirio Marine Protected Area, a 90-square-metre detached villa with an 80-square-metre heated infinity pool, offering breathtaking panoramic views of the Sicilian coast from Plemmirio to Capo Passero. The villa is surrounded by a private 8,000-square-metre park featuring an abundance of typical Sicilian vegetation (olive, carob and almond trees, Mediterranean pines, mulberry and fig trees, and a rock garden with Mediterranean scrub).
LocationFamilyOutdoor spaces

Casa Isola - Siracusa - beach 5 min walk
Welcome to Casa Isola! The house has been fully renovated in 2025 with the idea to create a peaceful space with loads of natural light, using neutral colours and earthy materials. It has a beautiful outdoor space to make the most of your stay in Sicily. We also spend our holidays in Casa Isola and we want you to feel at home as much as we do, so please enjoy it while taking good care of it!
LocationTVIndoor spaces

Biancapigna Holidays & Pool
Biancapigna Holidays is a charming cottage located in a quiet residential area very close to the Plemmirio cliffs where it is possible to admire breathtaking views. The house, all on one floor, has a floor area of approximately 85 m2, plus verandas and outdoor spaces with a large garden, swimming pool area, barbecue area and laundry room. Free parking opposite the house
FamilyLocationAir conditioning

Casa Francesca
Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.
FamilyValueAmenities
Popular amenities for Isola holiday rentals
Other great holiday rentals in Isola

Sky Rooftop Ortigia
LocationComfortHospitality

Aglaia apartment Ortigia Island terrace
LocationFamilyWalkability

150sqm 2BA Prime Location Car Access Dining Guide
LocationValueLong stay

Apartment in a villa by the sea and the beach
LocationParkingHospitality

Villa Il Carrubo with private pool Val di Noto
LocationValueSleep quality

Cortile Crocefisso apartment
FamilyValueNearby

San Corrado Suite
LocationNearbyView

Ortigia Prestige Apartment with a view
LocationIndoor spacesAmenities
Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Castello Ursino
- Etnaland
- Castello Maniace
- Greek Theatre of Syracuse
- Oasi Del Gelsomineto
- Nature reserve of Vendicari
- Sampieri Beach
- Fishmarket
- Spiaggia Vendicari
- Isola delle Correnti
- Aci Trezza
- Necropolis of Pantalica
- Temple of Apollo
- Noto Cathedral
- Monastery of San Nicolò l'Arena
- Noto Antica
- Cavagrande del Cassibile Nature Reserve
- Museo Archeologico Regionale Paolo Orsi
- Orto Botanico
- Riserva Naturale Oasi del Simeto
- Etnapolis
- Palazzo Platamone





