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House holiday rentals in Guadalupe

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe

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Guest favourite
The manicured garden features neatly trimmed hedges and a brick-laid patio. White metal chairs and tables are positioned among various plants and flower pots, creating serene sitting areas. The Victorian house is visible in the background, framed by lush greenery.
Home in Lompoc
4.95 out of 5 average rating, 328 reviews

1879 Victorian in Central Coast Wine Country

Lovely private 1879 Victorian built by Lompoc founder W.W. Broughton - with fully stocked kitchen, living room/ dining room, laundry room, full bathroom, back yard (lawn mowed Tuesdays, watering/ gardening is done generally in the mornings, cable TV, internet, set in spacious, beautifully manicured Victorian Gardens. Reservation includes two bedrooms with queen beds. Note: Entrance stairs may be difficult for those with limitations. No pets. Two triplexes with six renters are also on property.

Guest favourite
A sunset sky filled with vibrant colors casts a warm glow over the country house. The exterior is highlighted by large windows and a welcoming entrance. The driveway leads towards the home, bordered by manicured landscaping, set against a backdrop of rolling hills.
Home in Arroyo Grande
4.83 out of 5 average rating, 276 reviews

Coastal Getaway, Country House, near 101 FWY

Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Guest favourite
The spacious backyard is showcased, featuring a newly installed turf area and a sports court for activities. A covered patio is visible, providing shaded seating, and the home's modern design blends with surrounding greenery. Solar panels are installed on the roof.
Home in Nipomo
4.97 out of 5 average rating, 103 reviews

Gateway to SLO County with Pickleball & Game Room

Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

Superhost
A modern living area features a large, flat-screen TV against a white wall. A surfboard is mounted beside a fireplace, and a round glass-top coffee table is set on a blue-patterned area rug. Natural light filters through sheer curtains.
Home in Oceano
4.96 out of 5 average rating, 157 reviews

Casa Del Mar

Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Guest favourite
A spacious bed is centered in the room, adorned with white linens and accented by two light blue pillows. A cozy yellow blanket is draped across the foot of the bed. Two bedside tables with modern lamps provide soft lighting, enhancing the calm atmosphere.
Home in Orcutt
4.95 out of 5 average rating, 197 reviews

Luxe Hideaway: BBQ, Patio, Wineries, 20 min Beach

Kick back & relax in this calm, modern space. Enjoy the privacy of your own home with contactless check-in, high speed internet, comfortable beds, pull-out memory foam sofa sleeper for added guests, full kitchen just waiting for your culinary desires, and a patio with dining set for 6 Santa Maria is located near many wineries, hiking/mountain biking trails and we're only 20 minutes to the beach. Enjoy being centrally located while you explore the beautiful central coast.

Top Guest favourite
A living area is shown with a sectional sofa arranged around a coffee table. Large windows provide natural light and offer views of the outdoor space. A clock is mounted on the wall, accompanied by decorative accents, while a door leads to the outdoor patio.
Home in Nipomo
4.97 out of 5 average rating, 104 reviews

Pleasant hills, king suite, EV Charger

Come relax and enjoy our peaceful home and outdoor spaces. We are located halfway between Los Angeles and San Francisco. Here you can experience the beautiful Central Coast including wineries, Beaches, Cal Poly and golf courses. We are located in a quiet neighborhood adjacent to an organic blackberry farm. Easy access to the 101 Freeway, where you can easily visit Santa Barbara or Paso Robles wine regions. Our home is FULLY Air Conditioned for your comfort.

Guest favourite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 340 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Guest favourite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.93 out of 5 average rating, 226 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Guest favourite
A spacious backyard is presented, featuring a lush green lawn and a winding pathway that leads to a rustic tiki hut with a firepit. Surrounding trees provide shade, and flower beds add color to the landscape.
Home in Arroyo Grande
4.89 out of 5 average rating, 605 reviews

( Sanitized!) Country home w/ backyard tiki hut

As 13-time Superhosts we welcome you! This adorable home is perfect for couples or families. Enjoy the relaxation of country living; yet just 15 mins from the beaches. We have included everything we could think of for you to have a stress-free and fun vacation; the softest of beds & linens, a fully-stocked kitchen, games, fire-pit , satellite tv/smart tv and beach gear.

Guest favourite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 122 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Superhost
A spacious studio is presented with warm wood flooring and ample natural light from multiple windows. A queen bed is positioned beside a wooden table with chairs. An acoustic guitar leans against the wall, and a TV is mounted on a shelf nearby.
Home in San Luis Obispo
4.8 out of 5 average rating, 955 reviews

Spacious Slo Studio: AirBnB Dream

Solo or couple travelers this place is for you and what Air BNB was originally all about. Unique, friendly space that has taken on energy from all the travelers. Check in 3pm. Peep reviews, take it from patrons! BUSINESS LICENSE #: Zero Zero Zero One Six One Zero Eight Two Zero One Nine

Top Guest favourite
A spacious home is set against a clear blue sky, surrounded by lush trees and flowering plants. The well-maintained yard features a gravel pathway leading to a large patio area, offering ample space for outdoor relaxation and gatherings.
Home in Nipomo
4.97 out of 5 average rating, 104 reviews

Beach, Wine Country, & Golf adjacent home for 8

Full home privacy, with a backyard to properly relax in after a day spent exploring the beautiful Central Coast. Enjoy the quiet of Nipomo in this country living style home. Pour some wine, light up the fire pit, toss some horseshoes, and kick back at Tejas Place!

Popular amenities for Guadalupe house rentals