Pet-friendly holiday rentals in Cape Girardeau County

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Top-rated pet-friendly home rentals in Cape Girardeau County

Guests agree: These pet-friendly homes are highly rated for location, cleanliness and more.

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Superhost
Home in Cape Girardeau
4.79 out of 5 average rating, 14 reviews

Historic Riverside Getaway

Step into a beautifully restored early 20th-century gem, where classic architecture meets cozy, modern interiors. Sip your morning coffee on the balcony with river views, unwind in a stylish lounge, and enjoy the warmth of wood floors, plush rugs, and curated decor. With a full kitchen, spacious bathroom, and serene bedroom, this space is perfect for couples, solo travelers, or remote workers seeking peace and character. Book your stay where comfort and charm meet right in the heart of downtown

Superhost
A spacious living room showcases comfortable seating arranged around a central coffee table. Natural light pours in through large windows, illuminating a decorative area rug. A ceiling fan adds to the home's ambiance, while a dining area can be seen in the background.
Bungalow in Cape Girardeau
4.96 out of 5 average rating, 23 reviews

Large Home next to Southeast Hospital - 2 King Bed

Enjoy exploring Cape Girardeau with your group of friends or family by spreading out in our spacious 3-bedroom home! Just moments from downtown, this home is the perfect place to get ready for your night out on Broadway, or to relax as a group while using our open space living room & fully equipped kitchen. We have generous sleeping arrangements with large bedrooms, multiple King size beds, or cozy up on the couch to watch your favorite show or spend some quiet time relaxing in the den in fron

Top Guest favourite
A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.
Apartment in Cape Girardeau
4.95 out of 5 average rating, 280 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Top Guest favourite
A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.
Barn in Cape Girardeau
4.94 out of 5 average rating, 236 reviews

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Guest favourite
Tiny home in Cape Girardeau
4.92 out of 5 average rating, 13 reviews

Cute Purple Tiny House in Tiny Home Village

Enjoy nature as you stay in our unique tiny home village. Nestled between Boulder Creek & lovely natural rock formations, we are proud to share our beautiful property. The Crystal Palace is our purple house with a large scenic, round window on a unique board walk. This property is handicap accessible with a queen bed & a futon in the living area. It can sleep 3 people, but is ideal for 1 or 2. This unit has a bathroom, small kitchenette with a larger mini fridge & microwave.

Top Guest favourite
An open living area is presented with a neutral color palette, featuring a spacious sofa and a dining table set for four. A ceiling fan is visible above, and a well-equipped kitchen is located in the background. Light enters through large windows, enhancing the bright atmosphere.
Guesthouse in Jackson
5 out of 5 average rating, 9 reviews

Gray House Cottage - A peaceful, happy place

Gray House Cottage is a safe, quiet, self contained unit Fast WiFi A private entrance, driveway & covered parking No Tobacco, Cannabis or e-cigarettes No pets 1.6 miles to I-55 Exit 105 10 minutes to Jackson MO 15 minutes to Cape Girardeau MO 10 minutes to Procter & Gamble/Mondi plant facilities Minutes away from city central amenities, golf courses, SEMO State University, sports complexes, wineries, unique eateries, casino, Trail of Tears State Park & Mississippi River

Superhost
Home in Cape Girardeau
4.88 out of 5 average rating, 16 reviews

Cottage Near Casino

Welcome to your cozy cottage with a delightful retro feel, conveniently located near the Casino, Downtown, and SEMO University. You'll be greeted by the inviting sight of a white fence that surrounds the property, adding a touch of quaint charm to home away from home. This home features 2 bedrooms, 1 full bathroom and the convenience of main floor laundry. This is the perfect haven for traveling nurses or professionals seeking a comfortable and stylish residence.

Superhost
A new hot tub is prominently featured on a wooden deck, surrounded by rustic red fencing. Chairs and a table are set nearby, creating a welcoming outdoor space. Lush greenery and trees provide a natural backdrop, enhancing the cabin's serene atmosphere.
Cabin in Cape Girardeau
4.91 out of 5 average rating, 288 reviews

Log Cabin w/ Hot tub - Near Casino & Downtown Cape

THE BEST GETAWAY HERE IN CAPE! Have a relaxing staycation here in Cape Girardeau Perfect for a QUICK GETAWAY for couples, families or friends 5 MINS to the casino, country club and downtown cape Very unique log home with a private bedroom queen size bed, pull-out queen size futon in the living room and twin size hide away SLEEPS 4. Pool table, darts, and a hot tub.There is a large deck and fire pit which has the feel of being in the woods.

Superhost
The cottage exterior presents a single-story structure with light blue siding and a dark roof. A wooden deck is located at the front, featuring a railing. The yard is grassy, bordered by a privacy fence, with a driveway visible beside the house.
Home in Cape Girardeau
4.82 out of 5 average rating, 134 reviews

Herman’s Cottage on the Corner

This beautifully remodeled 2 bed/1 bath home offering modern comfort and total convenience. Enjoy central air, stylish furnishings, and high-speed internet. The home features keyless entry, a fully fenced backyard, and a BBQ grill perfect for relaxing evenings. Conveniently located near shopping, dining, and local attractions. Fully furnished and move-in ready, this space is ideal for comfortable, hassle-free living.

Superhost
Home in Cape Girardeau
4.56 out of 5 average rating, 9 reviews

Happy home for traveling professionals

Keep it simple at this peaceful and centrally-located place. Perfect home for any travel nurses in the area and safe for children as well. Let our home become yours. It’s comfy and cozy. Located on a dead end road, there is very minimal traffic and it is very quiet. You’ll love the neighborhood deer and our big backyard. No cleaning fee! **No cats. I’m sorry.

Top Guest favourite
Farm stay in Jackson
4.93 out of 5 average rating, 28 reviews

The Cabins 1

You won’t forget the peaceful surroundings of this rustic destination. Get back to the simpler things in life. Relax and unwind on the covered porch or around a fire pit by the pond. Plenty of attractions to see, local places to eat along with numerous outdoor activities. All within 20-30 minutes. The good life is waiting for you!

Guest favourite
A charming brick home features a welcoming front porch supported by white columns. A neatly paved walkway leads to the entrance, surrounded by green grass and landscaped greenery. Large windows allow natural light to illuminate the interior spaces.
Home in Cape Girardeau
5 out of 5 average rating, 12 reviews

Relax Here! off Broadway

Relax here! Charming location near downtown riverfront Cape. Few minutes to Capaha Park, Southeast Missouri State University, food, and entertainment downtown. Within few minutes of Southeast and St. Francis hospital Capaha Park: This huge park includes play structures, basketball court, disc golf & fishing pond.

Popular amenities for Cape Girardeau County pet-friendly home rentals