
Pet-friendly holiday rentals in Cape Girardeau County
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Top-rated pet-friendly home rentals in Cape Girardeau County
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A-Frame tiny home in tiny home village
Enjoy nature as you stay in our unique tiny home village. Nestled between Boulder Creek and lovely natural rock formations, we are proud to share our beautiful property. The Mermaid is our bright yellow A-frame with a porch enveloped in nature featuring our Mermaid benches. With two bedrooms (both w/ queen beds), one bathroom and a futon in the living area, the Mermaid sleeps up to 5 people. The unit has a small kitchenette with a larger mini fridge, microwave, hotplate complete with dishes.

Brand new 2 bedroom unit right in downtown Cape.
This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

The Cottage, Rusted Route Farms
You won’t forget your time in this romantic, memorable place. The Cottage at Rusted Route Farms is a 1 bedroom beautiful suite on an old 10 acre farm history galore. A picturesque pond is settled next to The Market our onsite Restaurant that will be serving food and drinks to be ready on your arrival or for a certain time that you choose. The over 125 year old barn has been renovated to keep the history alive and is located here on site. This retreat is located right outside Cape Girardeau.

RiverSide Barn Suite on the Mississippi River.
The barn suite is a beautiful 2 bedroom apartment overlooking the Mississippi River and housed in a unique barn with its own separate entrance. The deck views are spectacular and takes sitting and relaxing to a new level. Our wine place “The RiverHouse “ is within walking distance with the best worldwide wines and menu in the area. www.theriverhousewineplace.com We are 12 minutes from Cape Girardeau and serviced by Lyft & Car-Go. You May contact us by text or call and available at any time.

Under the Stars - Farmhouse
Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

College town Charm: Minutes from Downtown Cape
EXCELLENT LOCATION near downtown riverfront Cape! Enjoy live music, local dining/coffee, shopping, casino, and seasonal steamboat rides downtown. Less than 5 min. from Southeast Missouri State University & Southeast Hospital. Centrally located near wedding venues: Rusted Route, Deerfield, Watersedge, Sweet Pecan, and Country Club. 2 blocks from scenic Capaha Park. Home to Capaha baseball. This huge park includes play structures, basketball court, disc golf & fishing pond.

Gray House Cottage - A peaceful, happy place
Gray House Cottage is a safe, quiet, self contained unit Fast WiFi A private entrance, driveway & covered parking No Tobacco, Cannabis or e-cigarettes No pets 1.6 miles to I-55 Exit 105 10 minutes to Jackson MO 15 minutes to Cape Girardeau MO 10 minutes to Procter & Gamble/Mondi plant facilities Minutes away from city central amenities, golf courses, SEMO State University, sports complexes, wineries, unique eateries, casino, Trail of Tears State Park & Mississippi River

Riverside Getaway | Near Campus & Downtown
Experience early-1900s architecture just steps from Cape Girardeau’s riverfront. This historic home blends original character with modern updates for a comfortable, well-located stay. Tall ceilings, classic trim, and natural light create a warm feel, while reliable Wi-Fi and updated finishes make it practical for weekend visits or longer stays. Whether you’re here for the Riverwalk, a campus event, or time downtown, this retreat offers charm and walkable convenience.

Cottage Near Casino
Welcome to your cozy cottage with a delightful retro feel, conveniently located near the Casino, Downtown, and SEMO University. You'll be greeted by the inviting sight of a white fence that surrounds the property, adding a touch of quaint charm to home away from home. This home features 2 bedrooms, 1 full bathroom and the convenience of main floor laundry. This is the perfect haven for traveling nurses or professionals seeking a comfortable and stylish residence.

Log Cabin w/ Hot tub - Near Casino & Downtown Cape
THE BEST GETAWAY HERE IN CAPE! Have a relaxing staycation here in Cape Girardeau Perfect for a QUICK GETAWAY for couples, families or friends 5 MINS to the casino, country club and downtown cape Very unique log home with a private bedroom queen size bed, pull-out queen size futon in the living room and twin size hide away SLEEPS 4. Pool table, darts, and a hot tub.There is a large deck and fire pit which has the feel of being in the woods.

Herman’s Cottage on the Corner
This beautifully remodeled 2 bed/1 bath home offering modern comfort and total convenience. Enjoy central air, stylish furnishings, and high-speed internet. The home features keyless entry, a fully fenced backyard, and a BBQ grill perfect for relaxing evenings. Conveniently located near shopping, dining, and local attractions. Fully furnished and move-in ready, this space is ideal for comfortable, hassle-free living.

Happy home for traveling professionals
Keep it simple at this peaceful and centrally-located place. Perfect home for any travel nurses in the area and safe for children as well. Let our home become yours. It’s comfy and cozy. Located on a dead end road, there is very minimal traffic and it is very quiet. You’ll love the neighborhood deer and our big backyard. No cleaning fee! **No cats. I’m sorry.
Popular amenities for Cape Girardeau County pet-friendly home rentals
Pet-friendly house rentals

*Convenient | Downtown-River-Casino-SEMO-Hospital

SEMO Redhawks Campus Home with Hot Tub

Private Main Level Nurse Retreat - Historic Home

Ace Of Hearts- 1 Bed 1 Bath

Greenway Getaway

All-Inclusive 1BR • Fast Wi-Fi • Near SEMO

Located near downtown and casino

Lucky Queen- 4-bedroom Steps away from the Casino
Private, pet-friendly home rentals

Cute Purple Tiny House in Tiny Home Village

College town Charm: Minutes from Downtown Cape

Brand new 2 bedroom unit right in downtown Cape.

The Cottage, Rusted Route Farms

Under the Stars - Farmhouse

Private Nurse Retreat 1 + Walk to SEMO Activities!

A-Frame tiny home in tiny home village

The Cabins 1
Destinations to explore
- Rentals with a washing machine and dryer Cape Girardeau County
- Rentals with a fireplace Cape Girardeau County
- Rentals with outdoor seating Cape Girardeau County
- Rentals with a patio Cape Girardeau County
- Family-friendly rentals Cape Girardeau County
- Apartment rentals Cape Girardeau County
- Rentals with a fire pit Cape Girardeau County
- Pet-friendly rentals Missouri
- Pet-friendly rentals United States



